Patents by Inventor Erhu Lu

Erhu Lu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Diphenyl substituted thiophene-2-amide derivatives and pharmaceutical compositions thereof useful as antimicrobial
    Patent number: 11306067
    Abstract: Compounds or pharmaceutical acceptable salts thereof of Formula (I), in which RM have the meaning described herein and pharmaceutical compositions thereof useful as antimicrobial and/or adjuvant:
    Type: Grant
    Filed: March 1, 2019
    Date of Patent: April 19, 2022
    Assignee: Denovamed Inc.
    Inventors: Fan Wu, Erhu Lu, Shengguo Sun, Christopher J. Barden
  • Diphenyl Substituted Thiophene-2-Amide Derivatives and Pharmaceutical Compositions Thereof Useful as Antimicrobial
    Publication number: 20210017147
    Abstract: Compounds or pharmaceutical acceptable salts thereof of Formula (I), in which RM have the meaning described herein and pharmaceutical compositions thereof useful as antimicrobial and/or adjuvant:
    Type: Application
    Filed: March 1, 2019
    Publication date: January 21, 2021
    Applicant: Denovamed Inc.
    Inventors: Fan WU, Erhu LU, Shengguo SUN, Christopher J. BARDEN
  • Anti-amyloid compounds containing benzofurazan
    Patent number: 9938249
    Abstract: In general, among other things, compounds of Formula I are provided: in which R11 is e.g., 4-(pyrrolidin-1-yl)piperidin-1-yl, N-methyl-3-(pyrrolidin-1-yl)propan-1-amino, N1,N1,N3-trimethylpropane-1,3-diamino, N,N-dimethylpiperidin-4-amino, 3-(pyrrolidin-1-ylmethyl)azetidin-1-yl, 3-(pyrrolidin-1-ylmethanon)azetidin-1-yl, or 3-(morpholin-1-ylmethyl)azetidin-1-yl; R13 is, e.g., phenyl optionally substituted with one or more substituents; and R12 and R14 are each independently hydrogen or alkyl. Methods of treatment are also provided.
    Type: Grant
    Filed: February 27, 2015
    Date of Patent: April 10, 2018
    Assignee: Treventis Corporation
    Inventors: Mark A. Reed, Thomas K. Wood, Scott C. Banfield, Christopher J. Barden, Arun Yadav, Erhu Lu, Fan Wu
  • ANTI-AMYLOID COMPOUNDS CONTAINING BENZOFURAZAN
    Publication number: 20170174641
    Abstract: In general, among other things, compounds of Formula I are provided: in which R11 is e.g., 4-(pyrrolidin-1-yl)piperidin-1-yl, N-methyl-3-(pyrrolidin-1-yl)propan-1-amino, N1,N1,N3-trimethylpropane-1,3-diamino, N,N-dimethylpiperidin-4-amino, 3-(pyrrolidin-1-ylmethyl)azetidin-1-yl, 3-(pyrrolidin-1-ylmethanon)azetidin-1-yl, or 3-(morpholin-1-ylmethyl)azetidin-1-yl; R13 is, e.g., phenyl optionally substituted with one or more substituents; and R12 and R14 are each independently hydrogen or alkyl. Methods of treatment are also provided.
    Type: Application
    Filed: February 27, 2015
    Publication date: June 22, 2017
    Applicant: Treventis Corporation
    Inventors: Mark A. Reed, Thomas K. Wood, Scott C. Banfield, Christopher J. Barden, Arun Yadav, Erhu Lu, Fan Wu
  • Antimicrobial/adjuvant compounds and methods
    Patent number: 9012655
    Abstract: Among other things, in general, antimicrobial and/or adjuvant compounds are provided according to Formula Ia: (Ia) in which E and R1-11 have the meanings described herein; and prodrugs and pharmaceutically acceptable salts thereof. Other formulae and methods of use are also provided.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: April 21, 2015
    Assignee: Denouamed, Inc.
    Inventors: Fan Wu, Erhu Lu, Christopher J. Barden
  • ANTIMICROBIAL/ADJUVANT COMPOUNDS AND METHODS
    Publication number: 20140309266
    Abstract: Among other things, in general, antimicrobial and/or adjuvant compounds are provided according to Formula Ia: (Ia) in which E and R1-11 have the meanings described herein; and prodrugs and pharmaceutically acceptable salts thereof. Other formulae and methods of use are also provided.
    Type: Application
    Filed: March 2, 2012
    Publication date: October 16, 2014
    Applicant: DENOVAMED INC.
    Inventors: Fan Wu, Erhu Lu, Christopher J. Barden
  • TERPENOID ANALOGUES AND USES THEREOF FOR TREATING NEUROLOGICAL CONDITIONS
    Publication number: 20130267571
    Abstract: The present application provides a terpene analogue of Formula (I) or a pharmaceutically acceptable isomer, salt or ester thereof, and methods and uses thereof for treating neurological conditions such as pain in general and neuropathic pain. These terpene analogues can also be used to treat other electrical disorders in the central and peripheral nervous system. Also provided are methods of synthesizing the terpene analogues of Formula I.
    Type: Application
    Filed: September 14, 2011
    Publication date: October 10, 2013
    Applicant: NeuroQuest Inc.
    Inventors: Mark A. Reed, Donald Weaver, Shengguo Sun, Alexander McLellan, Erhu Lu
  • Compounds and methods for treating protein folding disorders
    Patent number: 8362066
    Abstract: The invention is directed to compounds and methods for treating protein folder disorders. In certain embodiments the invention provides compounds and methods for treating neurodegenerative diseases such as Alzheimer's disease, tauopathy, cerebral amyloid angiopathy, Lewy body disease, dementia, Huntington's disease and prion-based spongiform encelopathy. The invention further provides compounds, methods and pharmaceutical compositions for inhibiting tau protein, A? protein or ?-synuclein protein aggregation.
    Type: Grant
    Filed: November 19, 2007
    Date of Patent: January 29, 2013
    Assignee: Treventis Corporation
    Inventors: Michael D. Carter, Donald F. Weaver, Sheila Marie H. Jacobo, Erhu Lu, Fuye Gao
  • COMPOUNDS AND METHODS FOR TREATING PROTEIN FOLDING DISORDERS
    Publication number: 20100144821
    Abstract: The invention is directed to compounds and methods for treating protein folder disorders. In certain embodiments the invention provides compounds and methods for treating neurodegenerative diseases such as Alzheimer's disease, tauopathy, cerebral amyloid angiopathy, Lewy body disease, dementia, Huntington's disease and prion-based spongiform encelopathy. The invention further provides compounds, methods and pharmaceutical compositions for inhibiting tau protein, A? protein or ?-synuclein protein aggregation.
    Type: Application
    Filed: November 19, 2007
    Publication date: June 10, 2010
    Applicant: Queen's University at Kingston
    Inventors: Michael D. Carter, Donald F. Weaver, Sheila Marie H. Jacobo, Erhu Lu, Fuye Gao
  • Treatment of protein folding disorders
    Publication number: 20070015813
    Abstract: In certain embodiments, the invention is directed to a method for treating a protein folding disorder comprising administering to a subject a compound of the formulas disclosed. In preferred embodiments, the compounds are bis-indole compounds.
    Type: Application
    Filed: May 30, 2006
    Publication date: January 18, 2007
    Applicant: QUEEN'S UNIVERSITY AT KINGSTON
    Inventors: Michael Carter, Mark Hadden, Donald Weaver, Sheila Jacobo, Erhu Lu