Abstract: Described herein are systems, methods, and non-transitory computer readable media for defining and executing functions for determining a matching entity that is relevant to an entity of interest when, for example, there is a significant number of intermediary links and entities between the matching entity and the entity of interest. A visual depiction of a path traversal from a seed input entity to an output matched entity can be presented to an end user in a manner that allows the end user to ascertain the sequence of intermediary links and entities that connect the matched entity to the seed entity.

Abstract: Disclosed herein are novel antioxidant inflammation modulators, including those of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds. Methods and intermediates useful for making the compounds, and methods of using the compounds and compositions thereof are also provided.

Abstract: A battery may be charged in accordance with a charging current profile and a charging thermal profile to increase the number of charge-discharge cycles the battery may perform, to reduce the effects of lithium plating on the performance of the battery, and to reduce the likelihood that dendrites will develop. Applying spikes in the charging current while charging in accordance with the charging profile further reduces the likelihood of developing dendrites.

Abstract: Described herein are systems, methods, and non-transitory computer readable media for defining and executing functions for determining a matching entity that is relevant to an entity of interest when, for example, there is a significant number of intermediary links and entities between the matching entity and the entity of interest. A visual depiction of a path traversal from a seed input entity to an output matched entity can be presented to an end user in a manner that allows the end user to ascertain the sequence of intermediary links and entities that connect the matched entity to the seed entity.

Abstract: Described is an active check valve that uses electro-magnetic actuation for operation. The valve includes a plunger assembly having a magnet in a sealed internal volume. The plunger assembly further includes a plunger tip that extends from either a plunger assembly housing or a sealing member. Although the plunger assembly is disposed in the solvent flow, the magnet is not exposed to the solvent. When the valve is actuated, the plunger tip moves the sealing member to open or close the valve. Optionally, an arming force may be applied to the sealing member in advance of opening or closing to reduce the subsequent additional force necessary to move the sealing member during opening or closing, thereby improving the accuracy of the solvent composition in liquid chromatography system applications.

Abstract: A method for cleansing a desired skin surface, and a device therefor, can include a base to house a jar for the cleansing liquid, a jar for the removed liquid and debris, a pump to deliver the cleansing liquid to a wand applicator, and a pump to suction the cleansing liquid and debris removed from the desired skin surface. The two pumps can be driven by separate motors to allow a user to separately control the amount of liquid dispensed and the magnitude of the suction force applied. The device can also include an infusion enhancer that assists in the opening of the pores of the desired skin surface or by tightening the desired skin surface. The device can further include a self-cleaning tip that allows a cleaning solution to be immediately recycled through the system into the jar for the removed liquid and debris.

Abstract: The disclosure relates to a thin layer comprising a catechol containing polymer or oligomer, as well as methods of making and using the thin layer comprising the catechol containing polymer or oligomer. The disclosure also relates to a thin layer comprising a catechol containing polymer or oligomer adjacent to and in contact with a bulk adhesive layer. The layers demonstrate improved adhesion between coral and coral-like materials.

Abstract: Compositions and methods for treating Duchenne Muscular Dystrophy (DMD) are encompassed.

Abstract: A continuous flow mixer for use in a chromatography system includes a first channel structure located between a mixer inlet and a mixer outlet. The first channel structure includes a first inlet branch, a second inlet branch, a plurality of outlet branches including at least a first outlet branch and a second outlet branch, a first plurality of branches splitting from the first inlet branch, each branch of the first plurality of branches connected to a different of the plurality of outlet branches, and a second plurality of branches splitting from the second inlet branch, each branch of the second plurality of branches connected to a different of the plurality of outlet branches. At least two branches of the first and second plurality of branches that are connected to the first outlet branch are offset in fluid residence time through the at least two branches.

Abstract: This invention provides, but is not limited to, novel oleanolic acid derivatives having the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds, methods and intermediates useful for making the compounds, and methods of using the compounds and compositions.

Abstract: Aspects of the present invention provide a display support arm assembly that includes a proximal housing supporting at least one proximal shaft, a distal housing spaced from the proximal housing and supporting at least one distal shaft, and at least one link extending from the at least one proximal shaft to the at least one distal shaft. The at least one link is coupled for pivotal movement about an axis of the at least one proximal shaft. The display support assembly also includes a gas strut extending between the proximal housing and the distal housing. The gas strut provides substantially constant force throughout a range of the vertical adjustment of the display support arm. The display support assembly further includes at least one torque element associated with either or both of the at least one proximal shaft and the at least one distal shaft.

Abstract: Aspects of the present invention provide a display support arm assembly that includes a proximal housing supporting at least one proximal shaft, a distal housing spaced from the proximal housing and supporting at least one distal shaft, and at least one link extending from the at least one proximal shaft to the at least one distal shaft. The at least one link is coupled for pivotal movement about an axis of the at least one proximal shaft. The display support assembly also includes a gas strut extending between the proximal housing and the distal housing. The gas strut provides substantially constant force throughout a range of the vertical adjustment of the display support arm. The display support assembly further includes at least one torque element associated with either or both of the at least one proximal shaft and the at least one distal shaft.

Abstract: Aspects of the present invention provide a display support arm assembly that includes a proximal housing supporting at least one proximal shaft, a distal housing spaced from the proximal housing and supporting at least one distal shaft, and at least one link extending from the at least one proximal shaft to the at least one distal shaft. The at least one link is coupled for pivotal movement about an axis of the at least one proximal shaft. The display support assembly also includes a gas strut extending between the proximal housing and the distal housing. The gas strut provides substantially constant force throughout a range of the vertical adjustment of the display support arm. The display support assembly further includes at least one torque element associated with either or both of the at least one proximal shaft and the at least one distal shaft.

Abstract: Systems, methods, and non-transitory computer-readable media can obtain data form one or more data sources. The data from the one or more data sources can be processed into one or more data records. Each data record can include at least an identification, a data type, and data to be stored. The data records can be organized into a tree data structure. The tree data structure can be stored as an intermediate data layer in a data analysis platform.

Abstract: Disclosed herein are solvent reservoir systems for steady flow delivery and simultaneous monitoring of solvent level and solvent density within the solvent reservoir systems and methods for monitoring the solvent reservoir systems and providing feedback to a user or adjusting the systems in response to the monitored characteristics.

Abstract: Disclosed herein are novel antioxidant inflammation modulators, including those of the formula: wherein the variables are defined herein. Also provided are pharmaceutical compositions, kits and articles of manufacture comprising such compounds. Methods and intermediates useful for making the compounds, and methods of using the compounds and compositions thereof are also provided.

Abstract: The present invention relates generally to the compound: N-((4aS,6aR,6bS,8aR,12aS,14aR,14bS)-11-cyano-2,2,6a,6b,9,9,12a-heptamethyl-10,14-dioxo-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,12a,14,14a,14b-octadecahydropicen-4a-yl)-2,2-difluoropropanamide, polymorphic forms thereof, methods for preparation and use thereof, pharmaceutical compositions thereof, and kits and articles of manufacture thereof.

Abstract: Aspects of the present invention provide a display support arm assembly that includes a proximal housing supporting at least one proximal shaft, a distal housing spaced from the proximal housing and supporting at least one distal shaft, and at least one link extending from the at least one proximal shaft to the at least one distal shaft. The at least one link is coupled for pivotal movement about an axis of the at least one proximal shaft. The display support assembly also includes a gas strut extending between the proximal housing and the distal housing. The gas strut provides substantially constant force throughout a range of the vertical adjustment of the display support arm. The display support assembly further includes at least one torque element associated with either or both of the at least one proximal shaft and the at least one distal shaft.