Patents by Inventor Eric A. Appel

Eric A. Appel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220125886
    Abstract: Compositions and methods for treating diabetes are disclosed. In particular, the invention relates to co-formulations of amylin analogues with insulin analogues for treatment of diabetes.
    Type: Application
    Filed: February 12, 2020
    Publication date: April 28, 2022
    Applicant: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Eric A. APPEL, Bruce A. BUCKINGHAM, David M. MAAHS, Caitlin MAIKAWA, Gillie Agmon ROTH
  • Publication number: 20220053073
    Abstract: The exemplary embodiments relate to improving the user experience associated with a digital platform. A first user device configured to remotely access a digital platform may receive a first signal broadcast by a second user device. Two or more types of communication protocols that are available to use for establishing a direct communication channel between the user devices are identified. One of the communication protocols is selected and a communication channel is established between the user devices in accordance with the selected communication protocol. The first user device then receives authentication information from the second user and establishes a session with the digital platform based on the authentication information received from the second user device.
    Type: Application
    Filed: August 14, 2020
    Publication date: February 17, 2022
    Inventors: Eric APPEL, Gary Karan, Joshua Phelps, Benjamin Manning, James Corrigan-Colville
  • Publication number: 20210369633
    Abstract: Network materials which exhibit both shear thinning and self-healing properties are disclosed. The networks contain particles and gel-forming compounds. The networks are useful for a variety of biomedical uses, including drug delivery.
    Type: Application
    Filed: June 8, 2021
    Publication date: December 2, 2021
    Inventors: Eric A. Appel, Mark W. Tibbitt, Robert S. Langer
  • Patent number: 11045429
    Abstract: Network materials which exhibit both shear thinning and self-healing properties are disclosed. The networks contain particles and gel-forming compounds. The networks are useful for a variety of biomedical uses, including drug delivery.
    Type: Grant
    Filed: January 23, 2017
    Date of Patent: June 29, 2021
    Assignee: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: Eric A. Appel, Mark W. Tibbitt, Robert S. Langer
  • Publication number: 20200109253
    Abstract: The present invention provides moldable, fully scalable cellulose silica-based hydrogels for use as low-cost and safe carriers and aqueous viscosity modifiers in various industrial and medical applications.
    Type: Application
    Filed: December 10, 2019
    Publication date: April 9, 2020
    Inventors: Eric A. Appel, Anthony C. Yu
  • Patent number: 10590257
    Abstract: The present invention provides moldable, fully scalable cellulose silica-based hydrogels for use as low-cost and safe carriers and aqueous viscosity modifiers in various industrial and medical applications.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: March 17, 2020
    Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventors: Eric A. Appel, Anthony C Yu
  • Publication number: 20180086896
    Abstract: The present invention provides moldable, fully scalable cellulose silica-based hydrogels for use as low-cost and safe carriers and aqueous viscosity modifiers in various industrial and medical applications.
    Type: Application
    Filed: September 26, 2017
    Publication date: March 29, 2018
    Inventor: Eric A. Appel
  • Publication number: 20170319506
    Abstract: Network materials which exhibit both shear thinning and self-healing properties are disclosed. The networks contain particles and gel-forming compounds. The networks are useful for a variety of biomedical uses, including drug delivery.
    Type: Application
    Filed: January 23, 2017
    Publication date: November 9, 2017
    Inventors: Eric A. Appel, Mark W. Tibbitt, Robert S. Langer
  • Publication number: 20150110772
    Abstract: The invention provides hydrogel, wherein the hydrogel has a supramolecular cross-linked network obtainable or obtained from the complexation of an aqueous composition including a host, such as cucurbituril, and one or more polymers having suitable guest functionality. One or more polymers in the aqueous composition may have a molecular weight of 50 kDa or more, such as 200 kDa or more. The hydrogel may hold a component, such as a therapeutic compound or a biological molecule. The hydrogels are suitable for use in medicine.
    Type: Application
    Filed: February 20, 2013
    Publication date: April 23, 2015
    Inventors: Oren Scherman, Eric Appel, Xian Jun Loh, Frank Biedermann, Matthew Rowland
  • Patent number: 8757264
    Abstract: A wellbore fluid contains a viscosifying polymer in which portions of the polymer are connected through formation of an inclusion complex involving cucurbituril 8 (i.e. CB[8]) as host molecule. The fluid contains guest molecules with first and second guest groups covalently attached wherein at least one of the guest molecules comprises a polymer chain. The CB[8] host and the guest molecules attach together through reception of first and second guest groups within CB[8] host cavities, thereby connecting polymer chains together as a larger, supramolecular polymer and enhancing viscosity of the fluid. Polymer molecules may be synthetic polymers and guest groups may be attached to monomers before polymerization. Alternatively guest groups may be attached to existing polymers which may be polysaccharide.
    Type: Grant
    Filed: August 30, 2011
    Date of Patent: June 24, 2014
    Assignee: Schlumberger Technology Corporation
    Inventors: Oren A. Scherman, Eric Appel, Trevor Hughes
  • Publication number: 20120103615
    Abstract: A wellbore fluid contains a viscosifying polymer in which portions of the polymer are connected through formation of an inclusion complex involving cucurbituril 8 (i.e. CB[8]) as host molecule. The fluid contains guest molecules with first and second guest groups covalently attached wherein at least one of the guest molecules comprises a polymer chain. The CB [8] host and the guest molecules attach together through reception of first and second guest groups within CB[8] host cavities, thereby connecting polymer chains together as a larger, supramolecular polymer and enhancing viscosity of the fluid. Polymer molecules may be synthetic polymers and guest groups may be attached to monomers before polymerization. Alternatively guest groups may be attached to existing polymers which may be polysaccharide.
    Type: Application
    Filed: August 30, 2011
    Publication date: May 3, 2012
    Applicant: Schlumberger Technology Corporation
    Inventors: Oren A. Scherman, Eric Appel, Trevor Hughes
  • Patent number: 8013065
    Abstract: A method for making a multi-branched polymer includes reacting a first polymeric unit with a functional cyclic compound to form a functional macroinitiator compound with a cyclic moiety. The functional macroinitiator compound is reacted with an amine functional compound to open the cyclic moiety and form a first functional group and a second functional group. To form the branched polymer, at least one of a second polymeric unit is propagated from the first functional group and a third polymeric unit is propagated from the second functional group.
    Type: Grant
    Filed: June 9, 2009
    Date of Patent: September 6, 2011
    Assignees: International Business Machines Corporation, The Board of Trustees of the Leland Stanford Junior University
    Inventors: James L. Hedrick, Eric Appel, Robert D. Miller, Fredrik Nederberg, Robert M. Waymouth
  • Publication number: 20100311917
    Abstract: A method for making a multi-branched polymer includes reacting a first polymeric unit with a functional cyclic compound to form a functional macroinitiator compound with a cyclic moiety. The functional macroinitiator compound is reacted with an amine functional compound to open the cyclic moiety and form a first functional group and a second functional group. To form the branched polymer, at least one of a second polymeric unit is propagated from the first functional group and a third polymeric unit is propagated from the second functional group.
    Type: Application
    Filed: June 9, 2009
    Publication date: December 9, 2010
    Inventors: James L. Hedrick, Eric Appel, Robert D. Miller, Fredrik Nederberg, Robert M. Waymouth