Abstract: The present disclosure relates to, inter alia, a gel formulation in a package, the package may be pressurized. The formulation comprises one or more active agents and is co-mingled with a gas propellant prior to being filled under pressure into the package. The gas propellant is added in sufficient amounts to be dispersed in the formulation; the pressurized package is under sufficient pressure suitable to maintain the first gas propellant dispersed in the formulation. The pressurized package is under sufficient pressure to expel the formulation as a whipped gel formulation upon application of external force on the formulation in the package. The present disclosure also relates to, inter alia, a method of preparing the disclosed formulation; a package comprising the disclosed formulation, and a method of using the disclosed formulation.

Abstract: A system (93) monitors the break-up phase of an electrostatic deflection continuous ink jet printer to identify phase instability likely to be caused by a partial blockage of the jet-forming device (17). It ignores alternations between adjacent phase positions and brief unrepeated periods of phase disruption. Preferably it ignores phase changes caused by changes in other operational parameters of the printer, such as variations in ink pressure. Monitoring may be done in the printer (99) or in an external system (93), (95).

Abstract: The current at a deflection electrode 23, 25 of an electrostatic deflection continuous inkjet printer 127 is monitored. If the current reaches a level higher than normal for a clean print head but below the current required to trigger an automatic shutdown, a warning is generated. The warning indicates that an automatic shutdown is likely to follow unless the print head is cleaned. This allows the operator to shut the printer down in a planned manner for cleaning. The warning may be provided at the printer 127 or it may be provided by an external system 121, 129 which allows personnel who are not at the printer to be alerted. The monitoring may be done by the printer or information about the deflection electrode current may be provided to an external system 121, 129 that performs the monitoring.

Abstract: Disclosed are compounds of the formula: where variables Z, X, R15, R2, R3, and Rc are defined herein. Compounds disclosed herein are inhibitors of the beta-secretase enzyme and are therefore useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal.

Abstract: A method and apparatus for repairing the femur. A connector is provided having a claw-like member to engage with the greater trochanter. Along the body of the connector are a plurality of cable apertures and cable screws to receive and engage with cables that loop around the femur. Along the inferior end of the connector are bone screw slots and bone screws engaging the connector with the femur. The bone screws provide added support to the re-attached greater trochanter and provide support for periprosthetic fractures. The connector may be used to re-attach the greater trochanter by impacting a connector onto the greater trochanter, positioning the greater trochanter onto the femur, passing cables around the femur and through the connector, tensioning the cables to provide engagement between the greater trochanter and the femur, and attaching the connector to the femur using at least one bone screw.

Abstract: Disclosed is a method and apparatus for repairing the femur. A connector is provided having a claw-like member to engage with the greater trochanter. Along the body of the connector are a plurality of cable apertures and cable screws to receive and engage with cables that loop around the femur. Along the inferior end of the connector are bone screw slots and bone screws engaging the connector with the femur. The bone screws provide added support to the re-attached greater trochanter and provide support for periprosthetic fractures. The connector may be used to re-attach the greater trochanter by impacting a connector onto the greater trochanter, positioning the greater trochanter onto the femur, passing cables around the femur and through the connector, tensioning the cables to provide engagement between the greater trochanter and the femur, and attaching the connector to the femur using at least one bone screw.

Abstract: Staphylococcus aureus peptide deformylase has been crystallized, and the three-dimensional x-ray crystal structure has been solved to 1.9 ? resolution. The x-ray crystal structure is useful for solving the structure of other molecules or molecular complexes, and designing modifiers of peptide deformylase activity.