Abstract: A convertible beverage container package having an integrated cooler compartment is provided that is sized to contain a number of cans in a box shape during transit, storage, and sale and which can be converted to a portable cooler configured to receive ice for cooling the cans contained therein. The shape of the convertible beverage container package allows a compact package for storage and transport, which can be selectively expanded to receive ice. In some cases, the received ice may surround two or more sides of the beverage cans. In one case, the shape of the convertible beverage container package may direct ice inside the package to contact the canned beverages on at least three sides.

Abstract: Polymeric particles and scaffolds containing anesthetic agents, their use for sustained local delivery of anesthetic agents, reduction of pain killer addiction and addiction risk, and methods of fabricating and administering polymeric particles containing anesthetic agents are described herein.

Abstract: The present disclosure provides polymeric particles and scaffolds comprising a matrix and an anesthetic agent. In one embodiment, the matrix comprises a bioerodible polymer. The disclosure further relates to the use of the polymeric particles and scaffolds for sustained local delivery of anesthetic agents, reduction of pain killer addiction and addiction risk. The disclosure also provides methods of fabricating and administering polymeric particles and scaffolds containing an anesthetic agent described herein.

Abstract: A suture clip applier for applying a suture around a tubular tissue adjacent to an open lumen. The suture clip applier includes an elongated body having a tissue clinching mechanism at one end of the body. The tissue clinching mechanism comprises two arms that are movable between open and clinched positions. The suture clip applier includes a plurality of deformable suture clips mounted along a longitudinal length of the elongated body, wherein each suture clip is configured to be detachably positioned within an interior of the two arms and to be deformed between open and clinched positions in response to the two arms being moved between the open and clinched positions. The suture clip applier further includes a length of suture comprising a pre-formed adjustable fastening and a loop extending from the pre-formed adjustable fastening, the loop extending between the two arms.

Abstract: Polymeric particles and scaffolds containing anesthetic agents, their use for sustained local delivery of anesthetic agents, reduction of pain killer addiction and addiction risk, and methods of fabricating and administering polymeric particles containing anesthetic agents are described herein.

Abstract: A convertible beverage container package having an integrated cooler compartment is provided that is sized to contain a number of cans in a box shape during transit, storage, and sale and which can be converted to a portable cooler configured to receive ice for cooling the cans contained therein. The shape of the convertible beverage container package allows a compact package for storage and transport, which can be selectively expanded to receive ice. In some cases, the received ice may surround two or more sides of the beverage cans. In one case, the shape of the convertible beverage container package may direct ice inside the package to contact the canned beverages on at least three sides.