Abstract: A nanosecond pulser system is disclosed. In some embodiments, the nanosecond pulser system may include a nanosecond pulser having a nanosecond pulser input; a plurality of switches coupled with the nanosecond pulser input; one or more transformers coupled with the plurality of switches; and an output coupled with the one or more transformers and providing a high voltage waveform with a amplitude greater than 2 kV and a frequency greater than 1 kHz based on the nanosecond pulser input. The nanosecond pulser system may also include a control module coupled with the nanosecond pulser input; and an control system coupled with the nanosecond pulser at a point between the transformer and the output, the control system providing waveform data regarding an high voltage waveform produced at the point between the transformer and the output.

Abstract: Disclosed herein is a computer-implemented method of processing a query using a columnstore comprising a plurality of segments, the method comprising: receiving a query comprising a parameter; determining a key corresponding to the parameter; identifying a mapping structure, from a plurality of mapping structures, relating to said key, wherein each mapping structure corresponds to a respective segment of the columnstore; interrogating the identified mapping structure to determine a value corresponding to the key, wherein the value identifies an entry of an index table of a plurality of index tables that corresponds to the respective segment, wherein the entry of the index table identifies a row of the respective segment of the columnstore relating to the parameter; and retrieving data relating to the parameter from a data source based on data stored in the entry of the index table.

Abstract: An appliance air freshener having a frame and an air freshener medium. The frame defines an enclosure having a first face, and a second face opposite and spaced from the first face. The first face and the second face form an outer perimeter of the enclosure. The frame also defines a passage located within and spaced from the outer perimeter and extending along a passage axis from the first face to the second face. The air freshener medium is located within the enclosure.

Abstract: Disclosed herein is a computer-implemented method of processing a query using a columnstore comprising a plurality of segments, the method comprising: receiving a query comprising a parameter; determining a key corresponding to the parameter; identifying a mapping structure, from a plurality of mapping structures, relating to said key, wherein each mapping structure corresponds to a respective segment of the columnstore; interrogating the identified mapping structure to determine a value corresponding to the key, wherein the value identifies an entry of an index table of a plurality of index tables that corresponds to the respective segment, wherein the entry of the index table identifies a row of the respective segment of the columnstore relating to the parameter; and retrieving data relating to the parameter from a data source based on data stored in the entry of the index table.

Abstract: Disclosed is the treatment of the interior walls of a fluidic channel with a self-assembled monolayer of an organophosphorus acid.

Abstract: The present invention relates to complement component 1s (C1S) inhibitors for use in treatment of neurological diseases. The invention in particular relates to the use of C1S inhibitors for down-regulation of C1S expression. The invention also relates to nucleic acid molecules, which are complementary to C1S and capable of reducing the level of an C1S mRNA. Also comprised in the present invention is a pharmaceutical composition and its use in the treatment of neurological diseases.

Abstract: A nanosecond pulser system is disclosed. In some embodiments, the nanosecond pulser system may include a nanosecond pulser having a nanosecond pulser input; a plurality of switches coupled with the nanosecond pulser input; one or more transformers coupled with the plurality of switches; and an output coupled with the one or more transformers and providing a high voltage waveform with a amplitude greater than 2 kV and a frequency greater than 1 kHz based on the nanosecond pulser input. The nanosecond pulser system may also include a control module coupled with the nanosecond pulser input; and an control system coupled with the nanosecond pulser at a point between the transformer and the output, the control system providing waveform data regarding an high voltage waveform produced at the point between the transformer and the output.

Abstract: The present invention relates to complement C1r subcomponent (C1R) inhibitors for use in treatment of neurological diseases. The invention in particular relates to the use of C1R inhibitors for down-regulation of C1R expression. The invention also relates to nucleic acid molecules, which are complementary to C1R and capable of reducing the level of an C1R mRNA. Also comprised in the present invention is a pharmaceutical composition and its use in the treatment of neurological diseases.

Abstract: The present invention relates to complement component 4 (C4) inhibitors for use in treatment of a neurological disease. The invention in particular relates to the use of C4 inhibitors for down-regulation of C4 expression. The invention also relates to nucleic acid molecules, which are complementary to C4A and/or C4B and capable of reducing the level of an C4A and/or C4B mRNA. Also comprised in the present invention is a pharmaceutical composition and its use in the treatment of a neurological disease.

Abstract: A method, apparatus, and computer program, each configured for determining a travel propensity, the travel propensity being a distance a customer is willing to travel to redeem a renderable data object, are provided An exemplary method comprises classifying each of a plurality of geographic regions as one geographic region type of a plurality of geographic region types, mapping each of a plurality of redemption locations to a geographic region type, calculating, for a first geographic region type, a first distance that accounts for a predefined number of redemptions, determining a number of merchants having redemption locations within the first distance, calculating a second distance, from a center of a geographic region of the second geographic region type, necessary to include the number of merchants having redemption locations within the first distance, and assigning the second distance as the second geographic region type travel propensity.

Abstract: A method, apparatus, and computer program, each configured for determining a travel propensity, the travel propensity being a distance a customer is willing to travel to redeem a renderable data object, are provided An exemplary method comprises classifying each of a plurality of geographic regions as one geographic region type of a plurality of geographic region types, mapping each of a plurality of redemption locations to a geographic region type, calculating, for a first geographic region type, a first distance that accounts for a predefined number of redemptions, determining a number of merchants having redemption locations within the first distance, calculating a second distance, from a center of a geographic region of the second geographic region type, necessary to include the number of merchants having redemption locations within the first distance, and assigning the second distance as the second geographic region type travel propensity.

Abstract: Some embodiments include a pulsing power supply comprising a power supply and a transformer comprising: a transformer core; a primary winding wrapped around a portion of the transformer core, the primary winding having a first lead and a second lead; and a secondary winding wrapped around a portion of the transformer core. The pulsing power supply may also include a first switch electrically connected with the first lead of the primary winding and the power supply; and a second switch electrically connected with the second lead of the primary winding and the power supply, wherein the first switch and the second switch are opened and closed at different time intervals. The pulsing power supply may also include a pulsing output electrically coupled with the secondary winding of the transformer that outputs pulses having a voltage greater than about 2 kV and with pulse frequencies greater than 1 kHz.

Abstract: A method, apparatus, and computer program, each configured for gauging the health or quality of available supply, are provided. An exemplary method for generating a supply index indicative of a quality or health of supply by calculating and aggregating a supply metric calculated from a perspective of each of a plurality of individual customers to identify those locations where an increase in supply would most positively impact value to customers comprises identifying a location of a user, identifying at least a portion of each of one or more renderable data objects available to a user located at the location, applying a first weight to each of the portion of each of the one or more renderable data objects, calculating a total of each of the weights, applying a coverage cap to determine a capped total, and generating a supply index comprised of aggregated capped totals.

Abstract: Assemblies for DNA sequencing are provided comprising: (a) a substrate in the form of a flat plate; (b) a first coating layer applied to at least one surface of the substrate; and (c) a second coating layer applied to at least one surface of the first coating layer. The first coating layer comprises at least one of chromium oxide, tantalum pentoxide, Ta2O3 and TaO2, and the second coating layer comprises a silane compound. Also provided are mold assemblies comprising: (a) a substrate having an interior surface and an exterior surface; and (b) a mold release component comprising: (i) a first coating layer similar to that above, applied to the interior surface of the substrate; and (ii) a second coating layer applied to the first coating layer; wherein the second coating layer comprises an organo-silicon compound comprising at least one of a trihalosilane, a tetrahalosilane, an organosilane, and polymers thereof.

Abstract: Some embodiments include a plasma system comprising: a plasma chamber, an RF plasma generator, a bias generator, and a controller. The RF plasma generator may be electrically coupled with the plasma chamber and may produce a plurality of RF bursts, each of the plurality of RF bursts including RF waveforms, each of the plurality of RF bursts having an RF burst turn on time and an RF burst turn off time. The bias generator may be electrically coupled with the plasma chamber and may produce a plurality of bias bursts, each of the plurality of bias bursts including bias pulses, each of the plurality of bias bursts having an bias burst turn on time and an bias burst turn off time. In some embodiments the controller is in communication with the RF plasma generator and the bias generator that controls the timing of various bursts or waveforms.

Abstract: A method, apparatus, and computer program, each configured for gauging the health or quality of available supply, are provided. An exemplary method for generating a supply index indicative of a quality or health of supply by calculating and aggregating a supply metric calculated from a perspective of each of a plurality of individual customers to identify those locations where an increase in supply would most positively impact value to customers comprises identifying a location of a user, identifying at least a portion of each of one or more renderable data objects available to a user located at the location, applying a first weight to each of the portion of each of the one or more renderable data objects, calculating a total of each of the weights, applying a coverage cap to determine a capped total, and generating a supply index comprised of aggregated capped totals.

Abstract: Coated articles are provided comprising: (a) a substrate that demonstrates electrical conductivity; and (b) a coating layer applied to at least one surface of the substrate; wherein the coating layer demonstrates push-through electrical connectivity. The coated articles are particularly suitable for use in circuit assemblies.

Abstract: Techniques are provided for procuring healthcare services. A request to procure healthcare services for a patient is obtained. Provider subscription profiles corresponding to healthcare providers are generated based on subscriber information and provider subscription criteria. Bid auction invitations are generated by assigning a bid invitation ranking to each provider subscription profile and selecting healthcare providers to participate in a bid auction based on the bid invitation rankings. A pre-bill claim form is generated based on at least one bill template related to one or more medical classification codes related to the healthcare services. An auction engine is configured to conduct a bid auction among the selected healthcare providers, which results in a selection of a healthcare provider for the healthcare services and, upon confirmation that the healthcare services have been provided, a computing device or network platform is configured to take an action based on the pre-bill claim form.

Abstract: A nanosecond pulser system is disclosed. In some embodiments, the nanosecond pulser system may include a nanosecond pulser having a nanosecond pulser input; a plurality of switches coupled with the nanosecond pulser input; one or more transformers coupled with the plurality of switches; and an output coupled with the one or more transformers and providing a high voltage waveform with a amplitude greater than 2 kV and a frequency greater than 1 kHz based on the nanosecond pulser input. The nanosecond pulser system may also include a control module coupled with the nanosecond pulser input; and an control system coupled with the nanosecond pulser at a point between the transformer and the output, the control system providing waveform data regarding an high voltage waveform produced at the point between the transformer and the output.

Abstract: Disclosed herein is a computer-implemented method of processing a query using a columnstore comprising a plurality of segments, the method comprising: receiving a query comprising a parameter; determining a key corresponding to the parameter; identifying a mapping structure, from a plurality of mapping structures, relating to said key, wherein each mapping structure corresponds to a respective segment of the columnstore; interrogating the identified mapping structure to determine a value corresponding to the key, wherein the value identifies an entry of an index table of a plurality of index tables that corresponds to the respective segment, wherein the entry of the index table identifies a row of the respective segment of the columnstore relating to the parameter; and retrieving data relating to the parameter from a data source based on data stored in the entry of the index table.