Patents by Inventor Eric A. Klein
Eric A. Klein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10420939Abstract: Temporary or sub-threshold electrical stimulation to promote recovery of a damaged or injured nerve. Methods include promoting neuroregeneration of a nerve iatrogenically injured during a medical procedure performed on a target site of a patient's body. Methods include placing an electrical lead in electrical communication with the injured or damaged nerve. Methods further include temporarily stimulating the nerve and/or applying sub-threshold stimulation to the nerve to promote neuroregeneration of the nerve. The nerve can be a peripheral nerve.Type: GrantFiled: March 9, 2017Date of Patent: September 24, 2019Assignee: THE CLEVELAND CLINIC FOUNDATIONInventors: Bradley C. Gill, Yaw A. Nyame, Eric A. Klein
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Publication number: 20170281945Abstract: Temporary or sub-threshold electrical stimulation to promote recovery of a damaged or injured nerve. Methods include promoting neuroregeneration of a nerve iatrogenically injured during a medical procedure performed on a target site of a patient's body. Methods include placing an electrical lead in electrical communication with the injured or damaged nerve. Methods further include temporarily stimulating the nerve and/or applying sub-threshold stimulation to the nerve to promote neuroregeneration of the nerve. The nerve can be a peripheral nerve.Type: ApplicationFiled: March 9, 2017Publication date: October 5, 2017Inventors: Bradley C. Gill, Yaw A. Nyame, Eric A. Klein
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Patent number: 9717260Abstract: A kitchenware apparatus and container for producing fermented vegetables, such as sauerkraut, comprising a screw top or Mason jar, a threaded jar lid with moat and an oblong top slot opening, an inverted cup that fits within the moat, a plunger sized to fit within the neck of the jar and having a keyed handle that extends up through the slot in the lid, and a compression spring. The lid moat and inverted cup comprise an airlock or one way valve that allows fermentation gases to escape but prevents outside air from entering. The screw lid, spring and plunger comprise a press that compresses the fermenting vegetables to press juice from the vegetables and to hold the vegetables under the liquid surface to prevent mold or other spoilage and to prevent browning.Type: GrantFiled: November 1, 2013Date of Patent: August 1, 2017Inventors: Karen Wang Diggs, Eric A. Klein
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Patent number: 8917459Abstract: An ergonomic vertical redirection vision system comprises glasses or goggles with lenses modified to include a fresnel prism that vertically redirects light. The curved fresnel prism is a novel curved refractive element with unique advantages compared to a flat fresnel prism. The curved fresnel prism may be achromatized by the addition of an appropriate diffractive surface thereby creating a hybrid achromat or diffractive/refractive optical element (DROE). Looking through the modified eyewear will redirect the user's visual field up or down, depending on the configuration. Upward vision redirection improves ergonomics and aerodynamics for several sports including bicycle riding, swimming, downhill ski racing, and motorcycle racing. Downward vision redirection improves the ergonomics of reading a book, working on a laptop or pad computer, or taking notes in a class.Type: GrantFiled: May 23, 2012Date of Patent: December 23, 2014Inventors: Eric A. Klein, Adam Norton
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Publication number: 20140116271Abstract: A kitchenware apparatus and container for producing fermented vegetables, such as sauerkraut, comprising a screw top or Mason jar, a threaded jar lid with moat and an oblong top slot opening, an inverted cup that fits within the moat, a plunger sized to fit within the neck of the jar and having a keyed handle that extends up through the slot in the lid, and a compression spring. The lid moat and inverted cup comprise an airlock or one way valve that allows fermentation gases to escape but prevents outside air from entering. The screw lid, spring and plunger comprise a press that compresses the fermenting vegetables to press juice from the vegetables and to hold the vegetables under the liquid surface to prevent mold or other spoilage and to prevent browning.Type: ApplicationFiled: November 1, 2013Publication date: May 1, 2014Inventors: Karen Wang Diggs, Eric A. Klein
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Publication number: 20130222757Abstract: An ergonomic vertical redirection vision system comprises glasses or goggles with lenses modified to include a fresnel prism that vertically redirects light. The curved fresnel prism is a novel curved refractive element with unique advantages compared to a flat fresnel prism. The curved fresnel prism may be achromatized by the addition of an appropriate diffractive surface thereby creating a hybrid achromat or diffractive/refractive optical element (DROE). Looking through the modified eyewear will redirect the user's visual field up or down, depending on the configuration. Upward vision redirection improves ergonomics and aerodynamics for several sports including bicycle riding, swimming, downhill ski racing, and motorcycle racing. Downward vision redirection improves the ergonomics of reading a book, working on a laptop or pad computer, or taking notes in a class.Type: ApplicationFiled: May 23, 2012Publication date: August 29, 2013Inventors: Eric A. Klein, Adam Norton
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Publication number: 20130040369Abstract: The present invention provides for isolated nucleic acid sequences encoding viruses; isolated polypeptides comprising amino acid sequences of the virus; vectors comprising the viral nucleic acid sequences; cells comprising the vectors; antibodies and antigen binding fragments thereof which have binding specificity for the virus; methods of detecting or screening for the virus (e.g., in an individual); methods of identifying agents that inhibit the virus; methods of inducing an immune response to the virus; methods of treating disease associated with the presence of XMRV in an individual (e.g., cancer such as prostate cancer); methods of detecting asymptomatic cancer (e.g., prostate cancer); methods of identifying an individual at risk for developing cancer (e.g., prostate cancer); and kits for detecting the virus.Type: ApplicationFiled: July 17, 2012Publication date: February 14, 2013Applicants: The Regents of the University of California, The Cleveland Clinic FoundationInventors: Robert H. Silverman, Eric A. Klein, Graham Casey, Joseph DeRisi, Don Ganem
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Patent number: 8263085Abstract: The present invention provides for isolated nucleic acid sequences encoding viruses; isolated polypeptides comprising amino acid sequences of the virus; vectors comprising the viral nucleic acid sequences; cells comprising the vectors; antibodies and antigen binding fragments thereof which have binding specificity for the virus; methods of detecting or screening for the virus (e.g., in an individual); methods of identifying agents that inhibit the virus; methods of inducing an immune response to the virus; methods of treating disease associated with the presence of XMRV in an individual (e.g., cancer such as prostate cancer); methods of detecting asymptomatic cancer (e.g., prostate cancer); methods of identifying an individual at risk for developing cancer (e.g., prostate cancer); and kits for detecting the virus.Type: GrantFiled: September 24, 2007Date of Patent: September 11, 2012Assignees: The Cleveland Clinic Foundation, The Regents of the University of CaliforniaInventors: Robert H. Silverman, Eric A. Klein, Graham Casey, Joseph DeRisi, Don Ganem
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Publication number: 20100184015Abstract: The present invention relates to the identification of Xenotropic murine leukemia virus (XMRV) nucleic acid by polymerase chain reaction (PCR) analysis (e.g., real time PCR (RT/PCR); nested RT/PCR using Tth DNA polymerase and Hot start polymerase) and the uses thereof. In particular, the invention provides methods for the detection, and in particular early detection, of XMRV in RNA isolated from samples (e.g., urine samples; expressed prostate secretion (EPS)) of prostate cancer patients and normal individuals.Type: ApplicationFiled: December 22, 2009Publication date: July 22, 2010Inventors: Robert H. Silverman, Eric A. Klein, Christopher J. Weight, Carvell T. Nguyen, Jaydip Das Gupta
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Publication number: 20100166797Abstract: The present invention provides for isolated nucleic acid sequences encoding viruses; isolated polypeptides comprising amino acid sequences of the virus; vectors comprising the viral nucleic acid sequences; cells comprising the vectors; antibodies and antigen binding fragments thereof which have binding specificity for the virus; methods of detecting or screening for the virus (e.g., in an individual); methods of identifying agents that inhibit the virus; methods of inducing an immune response to the virus; methods of treating disease associated with the presence of XMRV in an individual (e.g., cancer such as prostate cancer); methods of detecting asymptomatic cancer (e.g., prostate cancer); methods of identifying an individual at risk for developing cancer (e.g., prostate cancer); and kits for detecting the virus.Type: ApplicationFiled: September 24, 2007Publication date: July 1, 2010Inventors: Robert H. Silverman, Eric A. Klein, Graham Casey, Joseph DeRisi, Don Ganem
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Patent number: 6991598Abstract: A miniature sexual aid device comprising a battery powered electric vibrator which attaches to the user's clothing. The sexual aid device includes a vibration motor, a button cell battery, a moisture resistant housing that contains the motor and battery, and a clip for attaching the device to the clothing material. The retaining clip may use magnets, friction or pins to attach to clothing material. The device is no larger than some jewelry broaches or pins and may be shaped and colored to be worn as an ornament.Type: GrantFiled: November 12, 2002Date of Patent: January 31, 2006Inventor: Eric A. Klein
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Publication number: 20030181835Abstract: A miniature sexual aid device is embodied in a battery powered electric vibrator which attaches to the user's finger. The sexual aid device includes a vibration motor, a button cell battery, a moisture resistant housing that contains the motor and battery, and a strap or ring for attaching the device to the finger or to another appendage. The motor is mounted transversely and contiguously with the battery. The retaining ring or strap may be offered in a variety of fixed sizes or may be adjustable to fit a variety of finger sizes. The device is no larger than some jewelry rings and may be shaped, colored, and ornamented to be worn on the finger as jewelry.Type: ApplicationFiled: November 25, 2002Publication date: September 25, 2003Inventor: Eric A. Klein
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Publication number: 20030181784Abstract: A miniature sexual aid device comprising a battery powered electric vibrator which attaches to the user's clothing. The sexual aid device includes a vibration motor, a button cell battery, a moisture resistant housing that contains the motor and battery, and a clip for attaching the device to the clothing material. The retaining clip may use magnets, friction or pins to attach to clothing material. The device is no larger than some jewelry broaches or pins and may be shaped and colored to be worn as an ornament.Type: ApplicationFiled: November 12, 2002Publication date: September 25, 2003Inventor: Eric A. Klein
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Patent number: 6572569Abstract: A sexual aid device comprising a battery powered electric vibrator which attaches to the user's tongue. The first embodiment attaches to the tongue using a post (18) which is inserted through a hole previously pierced in the tongue. The assembled device is shaped roughly like a dumbbell consisting of a post (18) with retainers mounted at either end. Post (18) has a diameter narrow enough to fit through the tongue hole, but the retainers have larger diameter and cannot slip through the hole. An electric vibrator motor (14) is incorporated into one of the retainers. At least one of the retainers must be removable to allow device insertion. An electric battery (13) may be mounted in the same retainer as the vibrator motor (14) or in the other retainer. The second embodiment attaches to the tongue using suction, constriction, and friction. The front end of the device houses a vibrator mechanism comprising a vibrator motor (14), battery (13), and switch (38) in a moisture resistant housing (11).Type: GrantFiled: April 29, 2002Date of Patent: June 3, 2003Inventor: Eric A. Klein
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Publication number: 20020115948Abstract: A sexual aid device comprising a battery powered electric vibrator which attaches to the user's tongue. The first embodiment attaches to the tongue using a post (18) which is inserted through a hole previously pierced in the tongue. The assembled device is shaped roughly like a dumbbell consisting of a post (18) with retainers mounted at either end. Post (18) has a diameter narrow enough to fit through the tongue hole, but the retainers have larger diameter and cannot slip through the hole. An electric vibrator motor (14) is incorporated into one of the retainers. At least one of the retainers must be removable to allow device insertion. An electric battery (13) may be mounted in the same retainer as the vibrator motor (14) or in the other retainer. The second embodiment attaches to the tongue using suction, constriction, and friction. The front end of the device houses a vibrator mechanism comprising a vibrator motor (14), battery (13), and switch (38) in a moisture resistant housing (11).Type: ApplicationFiled: April 29, 2002Publication date: August 22, 2002Inventor: Eric A. Klein
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Patent number: 6419649Abstract: A sexual aid device comprising a battery powered electric vibrator which attaches to the user's tongue. The first embodiment attaches to the tongue using a post (18) which is inserted through a hole previously pierced in the tongue. The assembled device is shaped roughly like a dumbbell consisting of a post (18) with retainers mounted at either end. Post (18) has a diameter narrow enough to fit through the tongue hole, but the retainers have larger diameter and cannot slip through the hole. An electric vibrator motor (14) is incorporated into one of the retainers. At least one of the retainers must be removable to allow device insertion. An electric battery (13) may be mounted in the same retainer as the vibrator motor (14) or in the other retainer. The second embodiment attaches to the tongue using suction, constriction, and friction. The front end of the device houses a vibrator mechanism comprising a vibrator motor (14), battery (13), and switch (38) in a moisture resistant housing (11).Type: GrantFiled: April 5, 2000Date of Patent: July 16, 2002Inventor: Eric A. Klein
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Patent number: 5751245Abstract: A route exception reporting apparatus is mounted in a mobile shipping vehicle having a predetermined geographic route. The shipping vehicle may be a self-propelled vehicle containing cargo or may also be a separable self-contained shipping container carried on a transportation vehicle. At least a portion of the predetermined route is stored in the apparatus on board the shipping vehicle. The apparatus is provided with a geographic locating means for determining the shipping vehicle location, a comparator means for comparing the shipping vehicle location with at least one point of the predetermined route and a communication means for communicating with a central station. The apparatus is configured to communicate the shipping vehicle location to the central station when the comparator means computes a difference between the shipping vehicle location at a particular point in time and the predetermined route point corresponding with that particular time point which exceeds a predetermined limit.Type: GrantFiled: March 7, 1996Date of Patent: May 12, 1998Assignee: Trimble Navigation Ltd.Inventors: James M. Janky, Eric A. Klein, John F. Schipper