Patents by Inventor Eric A. Klein

Eric A. Klein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10420939
    Abstract: Temporary or sub-threshold electrical stimulation to promote recovery of a damaged or injured nerve. Methods include promoting neuroregeneration of a nerve iatrogenically injured during a medical procedure performed on a target site of a patient's body. Methods include placing an electrical lead in electrical communication with the injured or damaged nerve. Methods further include temporarily stimulating the nerve and/or applying sub-threshold stimulation to the nerve to promote neuroregeneration of the nerve. The nerve can be a peripheral nerve.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: September 24, 2019
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventors: Bradley C. Gill, Yaw A. Nyame, Eric A. Klein
  • Publication number: 20170281945
    Abstract: Temporary or sub-threshold electrical stimulation to promote recovery of a damaged or injured nerve. Methods include promoting neuroregeneration of a nerve iatrogenically injured during a medical procedure performed on a target site of a patient's body. Methods include placing an electrical lead in electrical communication with the injured or damaged nerve. Methods further include temporarily stimulating the nerve and/or applying sub-threshold stimulation to the nerve to promote neuroregeneration of the nerve. The nerve can be a peripheral nerve.
    Type: Application
    Filed: March 9, 2017
    Publication date: October 5, 2017
    Inventors: Bradley C. Gill, Yaw A. Nyame, Eric A. Klein
  • Patent number: 9717260
    Abstract: A kitchenware apparatus and container for producing fermented vegetables, such as sauerkraut, comprising a screw top or Mason jar, a threaded jar lid with moat and an oblong top slot opening, an inverted cup that fits within the moat, a plunger sized to fit within the neck of the jar and having a keyed handle that extends up through the slot in the lid, and a compression spring. The lid moat and inverted cup comprise an airlock or one way valve that allows fermentation gases to escape but prevents outside air from entering. The screw lid, spring and plunger comprise a press that compresses the fermenting vegetables to press juice from the vegetables and to hold the vegetables under the liquid surface to prevent mold or other spoilage and to prevent browning.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: August 1, 2017
    Inventors: Karen Wang Diggs, Eric A. Klein
  • Patent number: 8917459
    Abstract: An ergonomic vertical redirection vision system comprises glasses or goggles with lenses modified to include a fresnel prism that vertically redirects light. The curved fresnel prism is a novel curved refractive element with unique advantages compared to a flat fresnel prism. The curved fresnel prism may be achromatized by the addition of an appropriate diffractive surface thereby creating a hybrid achromat or diffractive/refractive optical element (DROE). Looking through the modified eyewear will redirect the user's visual field up or down, depending on the configuration. Upward vision redirection improves ergonomics and aerodynamics for several sports including bicycle riding, swimming, downhill ski racing, and motorcycle racing. Downward vision redirection improves the ergonomics of reading a book, working on a laptop or pad computer, or taking notes in a class.
    Type: Grant
    Filed: May 23, 2012
    Date of Patent: December 23, 2014
    Inventors: Eric A. Klein, Adam Norton
  • Publication number: 20140116271
    Abstract: A kitchenware apparatus and container for producing fermented vegetables, such as sauerkraut, comprising a screw top or Mason jar, a threaded jar lid with moat and an oblong top slot opening, an inverted cup that fits within the moat, a plunger sized to fit within the neck of the jar and having a keyed handle that extends up through the slot in the lid, and a compression spring. The lid moat and inverted cup comprise an airlock or one way valve that allows fermentation gases to escape but prevents outside air from entering. The screw lid, spring and plunger comprise a press that compresses the fermenting vegetables to press juice from the vegetables and to hold the vegetables under the liquid surface to prevent mold or other spoilage and to prevent browning.
    Type: Application
    Filed: November 1, 2013
    Publication date: May 1, 2014
    Inventors: Karen Wang Diggs, Eric A. Klein
  • Publication number: 20130222757
    Abstract: An ergonomic vertical redirection vision system comprises glasses or goggles with lenses modified to include a fresnel prism that vertically redirects light. The curved fresnel prism is a novel curved refractive element with unique advantages compared to a flat fresnel prism. The curved fresnel prism may be achromatized by the addition of an appropriate diffractive surface thereby creating a hybrid achromat or diffractive/refractive optical element (DROE). Looking through the modified eyewear will redirect the user's visual field up or down, depending on the configuration. Upward vision redirection improves ergonomics and aerodynamics for several sports including bicycle riding, swimming, downhill ski racing, and motorcycle racing. Downward vision redirection improves the ergonomics of reading a book, working on a laptop or pad computer, or taking notes in a class.
    Type: Application
    Filed: May 23, 2012
    Publication date: August 29, 2013
    Inventors: Eric A. Klein, Adam Norton
  • Publication number: 20130040369
    Abstract: The present invention provides for isolated nucleic acid sequences encoding viruses; isolated polypeptides comprising amino acid sequences of the virus; vectors comprising the viral nucleic acid sequences; cells comprising the vectors; antibodies and antigen binding fragments thereof which have binding specificity for the virus; methods of detecting or screening for the virus (e.g., in an individual); methods of identifying agents that inhibit the virus; methods of inducing an immune response to the virus; methods of treating disease associated with the presence of XMRV in an individual (e.g., cancer such as prostate cancer); methods of detecting asymptomatic cancer (e.g., prostate cancer); methods of identifying an individual at risk for developing cancer (e.g., prostate cancer); and kits for detecting the virus.
    Type: Application
    Filed: July 17, 2012
    Publication date: February 14, 2013
    Applicants: The Regents of the University of California, The Cleveland Clinic Foundation
    Inventors: Robert H. Silverman, Eric A. Klein, Graham Casey, Joseph DeRisi, Don Ganem
  • Patent number: 8263085
    Abstract: The present invention provides for isolated nucleic acid sequences encoding viruses; isolated polypeptides comprising amino acid sequences of the virus; vectors comprising the viral nucleic acid sequences; cells comprising the vectors; antibodies and antigen binding fragments thereof which have binding specificity for the virus; methods of detecting or screening for the virus (e.g., in an individual); methods of identifying agents that inhibit the virus; methods of inducing an immune response to the virus; methods of treating disease associated with the presence of XMRV in an individual (e.g., cancer such as prostate cancer); methods of detecting asymptomatic cancer (e.g., prostate cancer); methods of identifying an individual at risk for developing cancer (e.g., prostate cancer); and kits for detecting the virus.
    Type: Grant
    Filed: September 24, 2007
    Date of Patent: September 11, 2012
    Assignees: The Cleveland Clinic Foundation, The Regents of the University of California
    Inventors: Robert H. Silverman, Eric A. Klein, Graham Casey, Joseph DeRisi, Don Ganem
  • Publication number: 20100184015
    Abstract: The present invention relates to the identification of Xenotropic murine leukemia virus (XMRV) nucleic acid by polymerase chain reaction (PCR) analysis (e.g., real time PCR (RT/PCR); nested RT/PCR using Tth DNA polymerase and Hot start polymerase) and the uses thereof. In particular, the invention provides methods for the detection, and in particular early detection, of XMRV in RNA isolated from samples (e.g., urine samples; expressed prostate secretion (EPS)) of prostate cancer patients and normal individuals.
    Type: Application
    Filed: December 22, 2009
    Publication date: July 22, 2010
    Inventors: Robert H. Silverman, Eric A. Klein, Christopher J. Weight, Carvell T. Nguyen, Jaydip Das Gupta
  • Publication number: 20100166797
    Abstract: The present invention provides for isolated nucleic acid sequences encoding viruses; isolated polypeptides comprising amino acid sequences of the virus; vectors comprising the viral nucleic acid sequences; cells comprising the vectors; antibodies and antigen binding fragments thereof which have binding specificity for the virus; methods of detecting or screening for the virus (e.g., in an individual); methods of identifying agents that inhibit the virus; methods of inducing an immune response to the virus; methods of treating disease associated with the presence of XMRV in an individual (e.g., cancer such as prostate cancer); methods of detecting asymptomatic cancer (e.g., prostate cancer); methods of identifying an individual at risk for developing cancer (e.g., prostate cancer); and kits for detecting the virus.
    Type: Application
    Filed: September 24, 2007
    Publication date: July 1, 2010
    Inventors: Robert H. Silverman, Eric A. Klein, Graham Casey, Joseph DeRisi, Don Ganem
  • Patent number: 6991598
    Abstract: A miniature sexual aid device comprising a battery powered electric vibrator which attaches to the user's clothing. The sexual aid device includes a vibration motor, a button cell battery, a moisture resistant housing that contains the motor and battery, and a clip for attaching the device to the clothing material. The retaining clip may use magnets, friction or pins to attach to clothing material. The device is no larger than some jewelry broaches or pins and may be shaped and colored to be worn as an ornament.
    Type: Grant
    Filed: November 12, 2002
    Date of Patent: January 31, 2006
    Inventor: Eric A. Klein
  • Publication number: 20030181835
    Abstract: A miniature sexual aid device is embodied in a battery powered electric vibrator which attaches to the user's finger. The sexual aid device includes a vibration motor, a button cell battery, a moisture resistant housing that contains the motor and battery, and a strap or ring for attaching the device to the finger or to another appendage. The motor is mounted transversely and contiguously with the battery. The retaining ring or strap may be offered in a variety of fixed sizes or may be adjustable to fit a variety of finger sizes. The device is no larger than some jewelry rings and may be shaped, colored, and ornamented to be worn on the finger as jewelry.
    Type: Application
    Filed: November 25, 2002
    Publication date: September 25, 2003
    Inventor: Eric A. Klein
  • Publication number: 20030181784
    Abstract: A miniature sexual aid device comprising a battery powered electric vibrator which attaches to the user's clothing. The sexual aid device includes a vibration motor, a button cell battery, a moisture resistant housing that contains the motor and battery, and a clip for attaching the device to the clothing material. The retaining clip may use magnets, friction or pins to attach to clothing material. The device is no larger than some jewelry broaches or pins and may be shaped and colored to be worn as an ornament.
    Type: Application
    Filed: November 12, 2002
    Publication date: September 25, 2003
    Inventor: Eric A. Klein
  • Patent number: 6572569
    Abstract: A sexual aid device comprising a battery powered electric vibrator which attaches to the user's tongue. The first embodiment attaches to the tongue using a post (18) which is inserted through a hole previously pierced in the tongue. The assembled device is shaped roughly like a dumbbell consisting of a post (18) with retainers mounted at either end. Post (18) has a diameter narrow enough to fit through the tongue hole, but the retainers have larger diameter and cannot slip through the hole. An electric vibrator motor (14) is incorporated into one of the retainers. At least one of the retainers must be removable to allow device insertion. An electric battery (13) may be mounted in the same retainer as the vibrator motor (14) or in the other retainer. The second embodiment attaches to the tongue using suction, constriction, and friction. The front end of the device houses a vibrator mechanism comprising a vibrator motor (14), battery (13), and switch (38) in a moisture resistant housing (11).
    Type: Grant
    Filed: April 29, 2002
    Date of Patent: June 3, 2003
    Inventor: Eric A. Klein
  • Publication number: 20020115948
    Abstract: A sexual aid device comprising a battery powered electric vibrator which attaches to the user's tongue. The first embodiment attaches to the tongue using a post (18) which is inserted through a hole previously pierced in the tongue. The assembled device is shaped roughly like a dumbbell consisting of a post (18) with retainers mounted at either end. Post (18) has a diameter narrow enough to fit through the tongue hole, but the retainers have larger diameter and cannot slip through the hole. An electric vibrator motor (14) is incorporated into one of the retainers. At least one of the retainers must be removable to allow device insertion. An electric battery (13) may be mounted in the same retainer as the vibrator motor (14) or in the other retainer. The second embodiment attaches to the tongue using suction, constriction, and friction. The front end of the device houses a vibrator mechanism comprising a vibrator motor (14), battery (13), and switch (38) in a moisture resistant housing (11).
    Type: Application
    Filed: April 29, 2002
    Publication date: August 22, 2002
    Inventor: Eric A. Klein
  • Patent number: 6419649
    Abstract: A sexual aid device comprising a battery powered electric vibrator which attaches to the user's tongue. The first embodiment attaches to the tongue using a post (18) which is inserted through a hole previously pierced in the tongue. The assembled device is shaped roughly like a dumbbell consisting of a post (18) with retainers mounted at either end. Post (18) has a diameter narrow enough to fit through the tongue hole, but the retainers have larger diameter and cannot slip through the hole. An electric vibrator motor (14) is incorporated into one of the retainers. At least one of the retainers must be removable to allow device insertion. An electric battery (13) may be mounted in the same retainer as the vibrator motor (14) or in the other retainer. The second embodiment attaches to the tongue using suction, constriction, and friction. The front end of the device houses a vibrator mechanism comprising a vibrator motor (14), battery (13), and switch (38) in a moisture resistant housing (11).
    Type: Grant
    Filed: April 5, 2000
    Date of Patent: July 16, 2002
    Inventor: Eric A. Klein
  • Patent number: 5751245
    Abstract: A route exception reporting apparatus is mounted in a mobile shipping vehicle having a predetermined geographic route. The shipping vehicle may be a self-propelled vehicle containing cargo or may also be a separable self-contained shipping container carried on a transportation vehicle. At least a portion of the predetermined route is stored in the apparatus on board the shipping vehicle. The apparatus is provided with a geographic locating means for determining the shipping vehicle location, a comparator means for comparing the shipping vehicle location with at least one point of the predetermined route and a communication means for communicating with a central station. The apparatus is configured to communicate the shipping vehicle location to the central station when the comparator means computes a difference between the shipping vehicle location at a particular point in time and the predetermined route point corresponding with that particular time point which exceeds a predetermined limit.
    Type: Grant
    Filed: March 7, 1996
    Date of Patent: May 12, 1998
    Assignee: Trimble Navigation Ltd.
    Inventors: James M. Janky, Eric A. Klein, John F. Schipper