Abstract: A vertical landing vehicle including an airframe forming a hull and having at least one wing coupled to the airframe, at least one proximity sensor coupled to the airframe, and a flight control system including a control processor and an operator interface, wherein the at least one proximity sensor is coupled to the control processor, wherein the control processor, based on signals from the at least one proximity sensor, is configured to generate, for presentation through the operator interface, situational awareness indications corresponding to portions of the hull sensed by the at least one proximity sensor and obstacles sensed by the at least one proximity sensor, and wherein the situational awareness indications comprise a terrain map overlay including positional relationships between the hull and the obstacles.

Abstract: A vertical landing vehicle including an airframe forming a hull and having at least one wing coupled to the airframe, at least one proximity sensor coupled to the airframe, and a flight control system including a control processor and an operator interface, wherein the at least one proximity sensor is coupled to the control processor, wherein the control processor, based on signals from the at least one proximity sensor, is configured to generate, for presentation through the operator interface, situational awareness indications corresponding to portions of the hull sensed by the at least one proximity sensor and obstacles sensed by the at least one proximity sensor, and wherein the situational awareness indications comprise a terrain map overlay including positional relationships between the hull and the obstacles.

Abstract: A vertical landing vehicle including an airframe forming a hull and having at least one wing coupled to the airframe, at least one proximity sensor coupled to the airframe, and a flight control system including a control processor and an operator interface, the at least one proximity sensor being coupled to the control processor, the control processor being configured to receive proximity signals from the at least one proximity sensor and present, through the operator interface and based on the proximity signals, situational awareness information of obstacles within a predetermined distance of the vertical landing vehicle relative to the hull and/or the at least one wing.

Abstract: A vertical landing vehicle including an airframe forming a hull and having at least one wing coupled to the airframe, at least one proximity sensor coupled to the airframe, and a flight control system including a control processor and an operator interface, the at least one proximity sensor being coupled to the control processor, the control processor being configured to receive proximity signals from the at least one proximity sensor and present, through the operator interface and based on the proximity signals, situational awareness information of obstacles within a predetermined distance of the vertical landing vehicle relative to the hull and/or the at least one wing.

Abstract: The present invention provides a mask for sealing an area around a patient's mouth and nose for delivery of an aerosol. The mask includes a mask body having an opening for reception of the aerosol and a mask seal configured to engage a patient's face around the nose and mouth. An adapter is arranged to be removably attached to the mask body for removably coupling the mask body to an aerosol delivery device.

Abstract: A nebulizer includes a piezoelectric transducer for aerosolizing a drug solution in a disposable cup module disposed above the transducer. Acoustic waves generated by the transducer propagate sequentially through transmitting medium, a first barrier, coupling medium, and a second barrier that forms part of the cup module, and into the interior of the cup module. The transducer at least partially comprises silver. The silver fluidly contacts the transmitting medium to discourage bacteria growth in the transmitting medium. The device includes electronics components that drive the transducer and measure an electrical characteristic associated with the transducer during operation. The electronics components measures changes in the electrical characteristic to determine when the drug solution level falls below a predetermined threshold, and deactivates the device accordingly.

Abstract: A nebulizer includes a piezoelectric transducer for aerosolizing a drug solution in a disposable cup module disposed above the transducer. Acoustic waves generated by the transducer propagate sequentially through transmitting medium, a first barrier, coupling medium, and a second barrier that forms part of the cup module, and into the interior of the cup module. The transducer at least partially comprises silver. The silver fluidly contacts the transmitting medium to discourage bacteria growth in the transmitting medium. The device includes electronics components that drive the transducer and measure an electrical characteristic associated with the transducer during operation. The electronics components measure changes in the electrical characteristic to determine when the drug solution level falls below a predetermined threshold, and deactivates the device accordingly.

Abstract: The present invention provides a drug delivery device that uses an aerosol generator to nebulize a drug solution. The drug delivery device includes differently sized guide tubes and separator walls to provide substantially consistent particles that can be varied in size by using different guide tubes. The drug delivery device also includes a barrier that separates a fluid contained in the device from the drug solution at least a portion of the barrier is formed from Polyetheretherketone. The present invention also has a drug detection device that can detect the volume of drug in the device or whether the barrier has been compromised.

Abstract: A drug delivery adapter is configured to facilitate the delivery of one or more medicaments to a subject being ventilated by a circuit (not shown). The circuit may be a ventilator circuit, or the like, configured to convey a pressurized flow of breathable gas to the airway of the subject. The ventilator circuit may form a flow path between a pressure generator and the airway of the subject to deliver a pressurized flow of breathable gas from the pressure generator to the airway of the subject. The drug delivery adapter, in particular, is configured to enable the delivery of one or more medicaments into the pressurized flow of breathable gas being conveyed to the subject by the circuit without compromising the integrity of the circuit through the introduction of ambient air. To facilitate this delivery, the drug delivery adapter is configured to dock one or more types of medicament dispenser.

Abstract: Various embodiments of a valved holding chamber and a mask for a respiratory drug delivery apparatus each having an exhalation valve element having two portions which, based on the movement thereof, encourages proper use of the device. Also, a valved holding chamber having an MDI adapter having a rigid outer portion and a flexible inner portion structured to receive and hold an outlet of an MDI. In addition, a mouthpiece assembly for a valved holding chamber that includes a main body portion and a mouthpiece portion having a plurality of legs for supporting the valved holding chamber in a first orientation and preventing it from freely rolling.

Abstract: A nebulizer includes a piezoelectric transducer for aerosolizing a drug solution in a disposable cup module disposed above the transducer. Acoustic waves generated by the transducer propagate sequentially through transmitting medium, a first barrier, coupling medium, and a second barrier that forms part of the cup module, and into the interior of the cup module. The transducer at least partially comprises silver. The silver fluidly contacts the transmitting medium to discourage bacteria growth in the transmitting medium. The device includes electronics components that drive the transducer and measure an electrical characteristic associated with the transducer during operation. The electronics components measure changes in the electrical characteristic to determine when the drug solution level falls below a predetermined threshold, and deactivates the device accordingly.

Abstract: The present invention provides a nebulizing drug delivery system for delivering an aerosolized drug to a user having various features to increase the capacity of the drug delivery device. The drug delivery system includes a heater to increase the viscosity of the drug, a double aerosolizing system to double the capacity of the device, and a valve system to continuously replenish drug to the aerosol generator thereby providing a high speed delivery.

Abstract: The present invention provides a nebulizing drug delivery system for delivering an aerosolized drug to a user having various features to increase the capacity of the drug delivery device. The drug delivery system includes a heater to increase the viscosity of the drug, a double aerosolizing system to double the capacity of the device, and a valve system to continuously replenish drug to the aerosol generator thereby providing a high speed delivery.

Abstract: A nebulizer includes a piezoelectric transducer for aerosolizing a drug solution in a disposable cup module disposed above the transducer. Acoustic waves generated by the transducer propagate sequentially through transmitting medium, a first barrier, coupling medium, and a second barrier that forms part of the cup module, and into the interior of the cup module. The transducer at least partially comprises silver. The silver fluidly contacts the transmitting medium to discourage bacteria growth in the transmitting medium. The device includes electronics components that drive the transducer and measure an electrical characteristic associated with the transducer during operation. The electronics components measure changes in the electrical characteristic to determine when the drug solution level falls below a predetermined threshold, and deactivates the device accordingly.

Abstract: The present invention pertains to a valved holding chamber suitable for use in an aerosol medication delivery system. The valved holding chamber includes a housing and a mouthpiece coupled to the housing. A one-way valve assembly is coupled to the housing, the mouthpiece, or both so that fluid flows in a first direction from the housing to the mouthpiece passes through the valve assembly but does not pass back into the housing. The valve assembly includes a conical flange disposed such that the conical flange tapers in the first direction to smooth the fluid flow in the first direction toward the patient. In a further embodiment, the mouthpiece includes an exhaust port defined in a conical collar portion of the mouthpiece, and an exhaust valve element is disposed over the exhaust port to provide a one-way flow of fluid from within the mouthpiece to ambient atmosphere via the exhaust port.

Abstract: The present invention provides a drug delivery device having a housing that includes a ventilator interface module and a base module removeably coupled to the ventilator interface module. An aerosol generator is disposed in the base module to nebulize a drug solution provided in the housing. The ventilator interface module has an outlet port through which nebulized particles of the drug solution can be communicated to a user, and an inlet port through which the housing receives intake gas. The housing has a flow path defined therein that directs intake gas from the inlet port to the outlet port such that the nebulized drug solution particles formed in the housing are motivated toward the outlet port when the base module is coupled to the ventilator interface module. A seal arrangement substantially seals the inlet port and outlet port from ambient atmosphere when the base module is uncoupled from the ventilator interface module, such that intake gas can be communicated from the inlet port to the outlet port.

Abstract: The present invention provides a nebulizing device with a housing that includes a mouthpiece module, an intermediate module, and a base module. An aerosol generator is in communication with a fluid. A barrier is disposed between the fluid and a drug solution provided within the housing. A signal transmitter and a signal receiver are carried by the housing. The signal is either initiated or terminated when one of the modules is separated or misaligned from the other modules. The device further includes a variable volume resilient structure disposed in communication with the fluid to provide volumetric relief in the event that the fluid expands.

Abstract: A translational language system and method for structuring irregular, or unstructured, information are provided. The language system comprising at least one compulsory characteristic for defining a particular nuance of an irregular communication; and at least one term or phrase corresponding to the at least one compulsory characteristic for further defining the particular nuance of the irregular communication.

Abstract: The present invention provides a mask for sealing an area around a patient's mouth and nose for delivery of an aerosol. The mask includes a mask body having an opening for reception of the aerosol and a mask seal configured to engage a patient's face around the nose and mouth. An adapter is arranged to be removably attached to the mask body for removably coupling the mask body to an aerosol delivery device.

Abstract: An apparatus and method for tracking the amount of medicament remaining with a metered dose inhaler. A dose indicator for a metered dose inhaler includes a housing having an upper portion and a lower portion, a spring element structured to moveably connect the upper portion with the lower portion, and a control module received within the housing and adapted to index a count representative of the number of doses of medicament remaining within the metered dose inhaler each time the dose indicator is cycled.