Patents by Inventor Eric A. STEFFEN

Eric A. STEFFEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR IMPROVED EXPRESSION OF RECOMBINANT PROTEINS
    Publication number: 20230287472
    Abstract: Provided herein are E. coli host strains with improved capacity for producing recombinant proteins.
    Type: Application
    Filed: April 12, 2023
    Publication date: September 14, 2023
    Applicant: SCARAB GENOMICS LLC
    Inventors: Frederick R. BLATTNER, Robert E. NOVY, David A. FRISCH, Charles LANDRY, Hyunsic CHOI, Eric A. STEFFEN, John BRANDON
  • Methods and compositions for improved expression of recombinant proteins
    Patent number: 11667944
    Abstract: Provided herein are methods for the improved production of periplasmic-targeted recombinant proteins in E. coli host strains. Also provided are E. coli host strains with improved capacity for producing recombinant proteins.
    Type: Grant
    Filed: September 4, 2018
    Date of Patent: June 6, 2023
    Assignee: SCARAB GENOMICS, LLC
    Inventors: Frederick R. Blattner, Robert E. Novy, David A. Frisch, Charles Landry, Hyunsic Choi, Eric A. Steffen, John Brandon
  • Methods and Compositions for Improved Expression of Recombinant Proteins
    Publication number: 20200318150
    Abstract: Provided herein are methods for the improved production of periplasmic-targeted recombinant proteins in E. coli host strains. Also provided are E. coli host strains with improved capacity for producing recombinant proteins.
    Type: Application
    Filed: September 4, 2018
    Publication date: October 8, 2020
    Applicant: SCARAB GENOMICS LLC
    Inventors: Frederick R. BLATTNER, Robert E. NOVY, David A. FRISCH, Charles LANDRY, Hyunsic CHOI, Eric A. STEFFEN, John BRANDON
  • Enhanced production of recombinant CRM197 in
    Patent number: 10479820
    Abstract: Rediced genome or native K12 strain E. coli bacteria comprising expression vectors encoding a recombinant CRM197 protein and their use in the production of CRM 197 is provided. The CRM 197 protein may be fused to a signal sequence that directs the expressed CRM197 protein to the periplasm of the E. coli host.
    Type: Grant
    Filed: March 2, 2015
    Date of Patent: November 19, 2019
    Assignee: SCARAB GENOMICS, LLC
    Inventors: Cristopher R. Blattner, David Frisch, Robert E. Novy, Terrance M. Henker, Eric A. Steffen, Frederick R. Blattner, Hyunsic Choi, Gyorgy Posfai, Charles F. Landry
  • BACTERIA WITH IMPROVED METABOLIC CAPACITY
    Publication number: 20180208933
    Abstract: E. coli bacteria comprising genetic modifications to enhance fermentability and production of protein and nucleic acids are provided.
    Type: Application
    Filed: February 23, 2018
    Publication date: July 26, 2018
    Applicant: SCARAB GENOMICS, LLC
    Inventors: Frederick R. BLATTNER, David A. FRISCH, Robert E. NOVY, Terrance M. HENKER, Eric A. STEFFEN, Jose A. SANCHEZ, Christopher R. BLATTNER, Hyunsic CHOI, Gyorgy POSFAI
  • Bacteria with improved metabolic capacity
    Patent number: 9902965
    Abstract: E. coli bacteria comprising genetic modifications to enhance fermentability and production of protein and nucleic acids are provided.
    Type: Grant
    Filed: November 13, 2014
    Date of Patent: February 27, 2018
    Assignee: SCARAB GENOMICS, LLC
    Inventors: Frederick R. Blattner, David A. Frisch, Robert E. Novy, Terrance M. Henker, Eric A. Steffen, Jose A. Sanchez, Christopher R. Blattner, Hyunsic Choi, Gyorgy Posfai
  • Enhanced Production of Recombinant CRM197 in E. coli
    Publication number: 20170073379
    Abstract: Rediced genome or native K12 strain E. coli bacteria comprising expression vectors encoding a recombinant CRM197 protein and their use in the production of CRM 197 is provided. The CRM 197 protein may be fused to a signal sequence that directs the expressed CRM197 protein to the periplasm of the E. coli host.
    Type: Application
    Filed: March 2, 2015
    Publication date: March 16, 2017
    Applicant: SCARAB GENOMICS, LLC
    Inventors: Cristopher R. BLATTNER, David FRISCH, Robert E. NOVY, Terrance M. HENKER, Eric A. STEFFEN, Frederick R. BLATTNER, Hyunsic CHOI, Gyorgy Posfai, Charles F. LANDRY
  • BACTERIA WITH IMPROVED METABOLIC CAPACITY
    Publication number: 20160298126
    Abstract: E. coli bacteria comprising genetic modifications to enhance fermentability and production of protein and nucleic acids are provided.
    Type: Application
    Filed: November 13, 2014
    Publication date: October 13, 2016
    Applicant: SCARAB GENOMICS, LLC
    Inventors: Frederick R. BLATTNER, David A. FRISCH, Robert E. NOVY, Terrance M. HENKER, Eric A. STEFFEN, Jose A. SANCHEZ, Christopher R. BLATTNER, Hyunsic CHOI, Gyorgy POSFAI