Abstract: A method and apparatus for monitoring brain activity of a user is disclosed. The apparatus includes a plurality of spatially separated emitters operable to generate infrared radiation. The apparatus also includes a plurality of spatially separated infrared radiation detectors, and a plurality of light pipes urged into contact with the user's scalp, each one of the plurality of emitters and detectors having an associated light pipe operable to couple infrared radiation from the emitter into the scalp or to couple infrared radiation from the scalp to the detector.

Abstract: A retainer, that holds a group of precision, off-the-shelf components in relative alignment so as to allow a standard key duplicating machine to function as a key code origination machine is disclosed. A person of ordinary skill in pinning a lock and operating a key duplicating machine is able to practice the invention. An aspect of the invention is that an ordinary, inexpensive key duplicating machine can be converted to code-cutting functionality with minimal cost, requiring no adaptation of key duplicating machine. Also disclosed are methods of positional registration, machine error compensation, and notch shaping.

Abstract: This disclosure features the use of one or more indazole-3-carboxamide compounds or salts or analogs thereof, in the treatment of one or more diseases or conditions independently selected from the group consisting of a tendinopathy, dermatitis, psoriasis, morphea, ichthyosis, Raynaud's syndrome, and Darier's disease; and/or for promoting wound healing. The methods include administering to a subject (e.g., a subject in need thereof) a therapeutically effective amount of one or more indazole-3-carboxamide compounds or salts or analogs thereof as described anywhere herein.

Abstract: A suturing device is provided that includes a suture positioning assembly that is slidably attachable to a sheath, a housing of the assembly includes a nose, a primary suture with connectors, an end effector, and an end effector actuator, an intravascular tip with a blood contact indicator on the nose, a slide limiter, and a fascia receiving surface, the intravascular tip is configured for insertion into the artery when disposed beneath a fascial layer, the fascia receiving surface is configured for accepting a perimeter edge of a dilated hole of the fascial layer, the housing nose further includes an intermediary suture having intermediary suture connectors, the primary suture connecters are configured for connection to the intermediary suture connectors, the end effector actuator is disposed to operate the end effector to condition the facial layer hole in a position for suturing by the intermediary suture connected to the primary suture.

Abstract: A catheter interface protection device can include a shield. The shield can include an open bottom, a transparent upper surface, sidewalls, and a cavity at least partially defined by the bottom, the upper surface, and the sidewalls. The device can include a vent. The device can include a clip, a tether, and a latch. A non-therapeutic method of protecting a catheter interface can include extending a catheter in the subject through a slot in a catheter interface protection device, wrapping the catheter at least partially around a clip of the catheter interface protection device, and securing a latch of the catheter interface protection device around the clip. A device for positioning a subject in a prone position can include a padded area including an opening configured to accommodate a catheter interface protection device.

Abstract: Embodiments provide a machine learning framework that enables developers to author and deploy machine learning pipelines into their applications regardless of the programming language in which the applications are structured. The framework may provide a programming language-specific API that enables the application to call a plurality of operators provided by the framework. The framework provides any number of APIs, each for a different programming language. The pipeline generated via the application is represented as an execution graph comprising node(s), where each node represents a particular operator. When a pipeline is submitted for execution, calls to the operators are detected, and nodes corresponding to the operators are generated for the execution graph.

Abstract: The invention relates to treatment of microorganisms from an activated sludge process operating with enhanced biological phosphorus removal in a reactor with baffles or other devices to induce similar plug-flow effort, designed to optimally release phosphorus and/or magnesium from the microorganisms with or without chemical addition. Further, the disclosure relates to a process designed to produce both a lower solids, phosphorus and magnesium enriched liquid stream and a higher solids, phosphorus and magnesium enriched stream. The reactor operates to give optimal performance by operating in a plug-flow mode.

Abstract: In non-limiting examples of the present disclosure, systems and methods for rewriting expressions utilizing cooperative visitors are provided. A data request may be received by a computing device, which may then be represented in a data structure, e.g., an expression tree, representative of the data request. A node within the data structure representative of the data request may be visited. Metadata associated with at least one cooperative visitor may be extracted from the node, and the node may then be transformed by applying the at least one cooperative visitor to the node.

Abstract: Embodiments provide a machine learning framework that enables developers to author and deploy machine learning pipelines into their applications regardless of the programming language in which the applications are structured. The framework may provide a programming language-specific API that enables the application to call a plurality of operators provided by the framework. The framework provides any number of APIs, each for a different programming language. The pipeline generated via the application is represented as an execution graph comprising node(s), where each node represents a particular operator. When a pipeline is submitted for execution, calls to the operators are detected, and nodes corresponding to the operators are generated for the execution graph.

Abstract: Sparse data handling and/or buffer sharing are implemented. Data may be buffered in reusable buffer arrays. Data may comprise fixed or variable length vectors, which may be represented as sparse or dense vectors in a values array and indices array. Data may be materialized from a dataview comprising a non-materialized view of data in a machine-learning pipeline by cursoring over rows of the dataview and calling delegate functions to compute data for rows in an active column. A buffer and/or its set of arrays storing a first vector may be reused for a second and additional vectors, for example, when the length of buffer arrays is equal to or greater than the length of the second and additional vectors, which may be selectively stored as sparse or dense vectors to fit the array set. Shared buffers may be passed as references between delegate functions for reuse.

Abstract: An efficient, streaming-based, lazily-evaluated machine learning (ML) framework is provided. An ML pipeline of operators produce and consume a chain of dataviews representing a computation over data. Non-materialized (e.g., virtual) views of data in dataviews permit efficient, lazy evaluation of data on demand regardless of size (e.g., in excess of main memory). Data may be materialized by DataView cursors (e.g., movable windows over rows of an input dataset or DataView). Computation and data movement may be limited to rows for active columns without processing or materializing unnecessary data. A chain of dataviews may comprise a chain of delegates that reference a chain of functions. Assembled pipelines of schematized compositions of operators may be validated and optimized with efficient execution plans. A compiled chain of functions may be optimized and executed in a single call. Dataview based ML pipelines may be developed, trained, evaluated and integrated into applications.

Abstract: This disclosure features the use of one or more indazole-3-carboxamide compounds or salts or analogs thereof, in the treatment of one or more diseases or conditions independently selected from the group consisting of a tendinopathy, dermatitis, psoriasis, morphea, ichthyosis, Raynaud's syndrome, and Darier's disease; and/or for promoting wound healing. The methods include administering to a subject (e.g., a subject in need thereof) a therapeutically effective amount of one or more indazole-3-carboxamide compounds or salts or analogs thereof as described anywhere herein.

Abstract: Performance parameters of a vehicle can be measured by an on-board performance parameter measuring device. The performance parameters can be measured while the vehicle is being used. The measured performance parameters of the vehicle can be transmitted to a computing device. The computing device can be configured to generate a user cost that reflects a cost for insuring the vehicle based on the measured performance parameters of the vehicle. A graphical user interface can be generated by the computing device for presentation to a user via a display device, that graphical user interface can include the user cost. An alternative transportation route for the journey and an alternative transportation cost for the journey can be determined and presented to the user through the graphical user interface.

Abstract: A method of treating the skin or hair on a dog containing an effective amount of an ectoparasiticide previously applied to the skin or hair, comprising applying a quantity of a cleansing composition directly to the skin or hair, wherein the treatment does not result in reducing the efficacy of the ectoparasiticide against adult fleas (C. felis) or adult ticks (R. sanguineus) below 90% efficacy for at least a month after application of the ectoparasiticide; wherein the cleansing composition comprises about 1-3% glycerin; about 2-4% silicone copolyol esters, water and is essentially free of surfactant.

Abstract: The invention relates to treatment of microorganisms from an activated sludge process operating with enhanced biological phosphorus removal in a reactor with baffles or other devices to induce similar plug-flow effort, designed to optimally release phosphorus and/or magnesium from the microorganisms with or without chemical addition. Further, the disclosure relates to a process designed to produce both a lower solids, phosphorus and magnesium enriched liquid stream and a higher solids, phosphorus and magnesium enriched stream. The reactor operates to give optimal performance by operating in a plug-flow mode.

Abstract: Described herein is an acoustic structural panel having a first exposed major surface opposite a second exposed major surface and side surfaces extending between the first and second exposed major surfaces, the acoustic structural panel comprising a first protective layer comprising at least a portion of the first exposed major surface, a second protective layer comprising at least a portion of the second exposed surface, a core structure located between the first and second protective layers, the core structure comprising, a foam body; and a fibrous body, wherein the first major exposed surface of the acoustic structural panel comprises a plurality of apertures exposing the fibrous body.

Abstract: A variable geometry contact lens structure having a thickness t sufficient to carry an active payload is constructed using layers of materials with high oxygen transmissibility and low oxygen transmissibility. The low transmissibility layer provide mechanical support for the active payload, and the high transmissibility layers provide adequate oxygen transmission to the cornea of the user's eye. The ratio of the thicknesses of the two layers changes abruptly at the boundaries between the payload and non-payload regions of the structure. For example, at a boundary of the payload region, a ratio of thicknesses of the high transmissibility layer t1 to thickness of the low transmissibility layer t2, R=t1/t2, changes by at least 2:1 over a lateral distance of not more than t.

Abstract: A method for customizing active contact lenses, such as contact lens displays, for a plurality of wearers includes the following: Contact lens precursors are obtained for a plurality of wearers. The contact lens precursors include active electronics. The same contact lens precursors are used as a starting point to generate active contact lenses for many different individuals, but they are processed into active contact lenses that are customized for each individual wearer.