Patents by Inventor Eric Brown
Eric Brown has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12268517Abstract: A method of delivering safe, suitable, and repeatable dosages to a subject for topical, oral, nasal, or pulmonary use and a device for droplet ejection includes a fluid delivery system capable of delivering a defined volume of the fluid in the form of droplets having properties that afford adequate and repeatable high percentage deposition upon application. The method and device include a housing, a reservoir disposed within the housing for receiving a volume of fluid, an ejector mechanism configured to eject a stream of droplets having an average ejected droplet diameter greater than 15 microns, the stream of droplets having low entrained airflow such that the stream of droplets deposit on the eye of the subject during use.Type: GrantFiled: May 13, 2021Date of Patent: April 8, 2025Assignee: Eyenovia, Inc.Inventors: Charles Eric Hunter, Bernard L. Ballou, Jr., Jurgen Klaus Vollrath, Arthur H. Tew, Joshua Richard Brown, James Thornhill Leath, Nathan R. Faulks, Bradley G. Johnson, J. Sid Clements, Phillip E. Russell, John H. Hebrank, Tsontcho Ianchulev, Mark Packer, Troy Elliott, Walter M. Fierson, Thomas J. Lindner
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Patent number: 12265559Abstract: An entity may want to capture personal data associated with one or more individuals. Personal data can include, for example, phone number(s), physical address(es), job titles, email address(es), or any other item of personal identifying information. The entity may be able to find such personal data via a variety of different data sources. For example, the entity may be able to find such personal data via tens, hundreds, thousands, or millions of different websites, documents, files, etc. The entity may also want to categorize the captured personal data by individual. For example, the entity may capture first personal data associated with a first individual from a number of different data sources and second personal data associated with a second individual from a number of different data sources.Type: GrantFiled: January 4, 2024Date of Patent: April 1, 2025Assignee: Strider Technologies, Inc.Inventors: Michael Brown, Greg Levesque, Eric Harnden, Jonathan Lentz
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Patent number: 12257320Abstract: Methods and compositions for gene therapy of retinal degeneration related to mutations in nicotinamide mononucleotide adenylyltransferase 1 (NMNAT1).Type: GrantFiled: March 11, 2021Date of Patent: March 25, 2025Assignee: Massachusetts Eye and Ear InfirmaryInventors: Eric A. Pierce, Luk H. Vandenberghe, Scott Greenwald, Emily Brown
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Publication number: 20250077932Abstract: A quantum element (QE) at a network node stores a first quantum state constituent (QSC) of an entangled quantum state characterized by a non-factorable quantum relationship among QSCs comprising the first QSC and a second QSC stored at another QE at another network node. Managing one or more quantum error management (QEM) operations includes: (1) providing a schedule for the QEM operations that is based at least in part on at least a portion of a time over which the first QSC is stored at the first QE and an estimated fidelity of the entangled quantum state after at least one of the QEM operations, or (2) providing a type of one or more QEM operations selected from two or more different types based at least in part on a number of resource quantum elements available at the first node after the first QSC is stored at the first QE.Type: ApplicationFiled: April 30, 2024Publication date: March 6, 2025Applicant: Aliro Technologies, Inc.Inventors: Keith KENEMER, Michael CUBEDDU, Matthew SKRZYPCZYK, Bruno RIJSMAN, Michelle CHALUPNIK, Eric BROWN
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Patent number: 12240857Abstract: Compounds of structural Formula I were developed for the treatment of infections by filoviruses including Ebolavirus and Marburgvirus, wherein, R1, R2, R3, X and Y are defined in the specification.Type: GrantFiled: July 12, 2018Date of Patent: March 4, 2025Assignee: Arisan Therapeutics Inc.Inventors: Michael Bruno Plewe, Eric Brown, Vidyasagar Gantla, Gregory Henkel, Kenneth McCormack, Nadezda Sokolova
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Publication number: 20250031737Abstract: Exemplary embodiments of the disclosure may be drawn to a device having an inlet and a chamber. Immobilized lipase, immobilized protease, and immobilized amylase may be contained within the chamber. The device may also include an outlet, wherein a flow path extends from the inlet, through the chamber, and to the outlet.Type: ApplicationFiled: October 11, 2024Publication date: January 30, 2025Applicant: Alcresta Therapeutics, Inc.Inventors: Eric FIRST, David BROWN, Albert Archie STONE
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Publication number: 20250025208Abstract: A surgical access assembly includes a housing, a tubular member, and a valve assembly. The tubular member extends from the housing. The valve assembly is positioned in the housing and includes a centering mechanism, a guard assembly disposed on a first side of the centering mechanism, and an instrument seal disposed on a second side of the centering mechanism. The instrument seal including petals that are arrange in an overlapping arrangement.Type: ApplicationFiled: October 2, 2024Publication date: January 23, 2025Applicant: Covidien LPInventors: Roy J. Pilletere, Garrett P. Ebersole, Eric Brown, Matthew A. Dinino, Jacob C. Baril, Richard C. Hart, Justin Thomas, Nicolette R. LaPierre
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Publication number: 20250017621Abstract: A surgical access assembly includes a cannula, a valve housing attached to the cannula, and a valve assembly positioned in the valve housing. The valve assembly includes a centering mechanism with a hoop and fingers, a ring with a flange at one end of the ring, a retainer having first and second discs, a guard having a frame and flaps attached to the frame, and a seal with petals attached to a support. The guard is at least partially disposed in the first disc and the seal is at least partially disposed in the second disc.Type: ApplicationFiled: September 30, 2024Publication date: January 16, 2025Applicant: Covidien LPInventors: Roy Pilletere, Jacob Baril, Garrett Ebersole, Matthew Dinino, Justin Thomas, Eric Brown, Nicolette LaPierre
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Publication number: 20240383997Abstract: Provided herein are engineered constant domains that have been engineered to comprise a blood brain barrier (BBB)-binding region, such a CDRH3 from an antibody that binds to a blood brain barrier target. Such engineered constant domains can be within a full length antibody or an antigen-binding fragment of an antibody such that the antibody or fragment is capable of binding to both the antigen of the antibody or fragment and the BBB target and is capable of being transported across the BBB.Type: ApplicationFiled: March 29, 2024Publication date: November 21, 2024Inventors: Eric BROWN, Hamid SALIMI, Wei-Hsien HO, Leonard PRESTA, Margaret TANG, Jeonghoon SUN
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Patent number: 12127762Abstract: A surgical access assembly includes a cannula, a valve housing attached to the cannula, and a valve assembly positioned in the valve housing. The valve assembly includes a centering mechanism with a hoop and fingers, a ring with a flange at one end of the ring, a retainer having first and second discs, a guard having a frame and flaps attached to the frame, and a seal with petals attached to a support. The guard is at least partially disposed in the first disc and the seal is at least partially disposed in the second disc.Type: GrantFiled: June 14, 2022Date of Patent: October 29, 2024Assignee: Covidien, LPInventors: Roy Pilletere, Jacob Baril, Garrett Ebersole, Matthew Dinino, Justin Thomas, Eric Brown, Nicolette LaPierre
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Patent number: 12127763Abstract: A surgical access assembly includes a housing, a tubular member, and a valve assembly. The tubular member extends from the housing. The valve assembly is positioned in the housing and includes a centering mechanism, a guard assembly disposed on a first side of the centering mechanism, and an instrument seal disposed on a second side of the centering mechanism. The instrument seal including petals that are arrange in an overlapping arrangement.Type: GrantFiled: May 3, 2023Date of Patent: October 29, 2024Assignee: Covidien LPInventors: Roy J. Pilletere, Garrett P. Ebersole, Eric Brown, Matthew A. Dinino, Jacob C. Baril, Richard C. Hart, Justin Thomas, Nicolette R. LaPierre
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Patent number: 12121299Abstract: In some embodiments, an apparatus comprises a stationary frame and a thermal ring. The thermal ring may be rotatably coupled to the stationary frame and disposed relative to the stationary frame such that the thermal ring and the stationary frame define an enclosure. The thermal ring may include a thermally-conductive substrate configured to be in thermal contact with a heat-generating component. Heat from the heat-generating component may be transferred to the stationary frame via the enclosure.Type: GrantFiled: May 6, 2021Date of Patent: October 22, 2024Assignee: RefleXion Medical, Inc.Inventor: Christopher Eric Brown
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Patent number: 12064141Abstract: A fixation device for folding a seal member includes a frame having a horizontal portion and an upright portion, a press assembly secured to the upright portion of the frame, and a nest assembly secured to the horizontal portion of the frame. The press assembly includes a handle assembly and an anvil assembly operably connected to the handle assembly. The nest assembly includes a clamping assembly, a folding assembly supported on the clamping assembly, a support assembly supported on the folding assembly, and a nest member. The support assembly includes a support plate and a seal clamp for securing a seal member.Type: GrantFiled: September 19, 2022Date of Patent: August 20, 2024Assignee: Covidien LPInventors: Roy J. Pilletere, Jason Mickus, Matthew A. Dinino, Eric Brown, Nicolette R. Lapierre, Jacob C. Baril, Justin Thomas
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Publication number: 20240238265Abstract: Compounds of Structural Formulae I, II, III, IV, V, VI, VII, and VIII were developed for the treatment of Ebolavirus infection, wherein, R1, R2, R8, X, Y, Q, W, and NR3aR3b are defined in the specification.Type: ApplicationFiled: June 7, 2021Publication date: July 18, 2024Applicant: Arisan Therapeutics Inc.Inventors: Eric Brown, Vidyasagar Reddy Gantla, Nadezda V. Sokolova, Gregory Henkel, Kenneth McCormack, Craig Robert Johnson
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Patent number: 12029449Abstract: Access assemblies includes an instrument valve housing and a valve assembly disposed within the cavity of the instrument valve housing. The valve assembly includes a guard assembly, a seal assembly disposed adjacent to the guard assembly, and a centering mechanism for maintaining the seal assembly and guard assembly centered within a cavity of the instrument valve. In embodiments, the seal assembly includes a plurality of seal sections that are movable from an unfolded configuration to folded configuration in which the seal assembly forms a hexagonal member defining an opening to facilitate sealed passage of a surgical instrument. The seal sections may include a tapered inner edge for engaging a surgical instrument inserted through the instrument valve housing.Type: GrantFiled: October 18, 2022Date of Patent: July 9, 2024Assignee: Covidien LPInventors: Roy J. Pilletere, Matthew A. Dinino, Garrett P. Ebersole, Kevin Desjardin, Justin Thomas, Jacob C. Baril, Nicolette R. LaPierre, Eric Brown
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Publication number: 20240198017Abstract: Features relating to a vaporizer device including a reusable vaporizer device body are provided. The vaporizer device includes a hybrid heating system including a convection heater and/or a conduction heater for rapidly heating vaporizable material stored in the vaporizer device.Type: ApplicationFiled: December 20, 2023Publication date: June 20, 2024Inventors: Eric Brown, David Carlberg, Scott Collins, Alexander Ringrose, Matthew J. Taschner, Brian M. Warren, Alexander Weiss
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Patent number: 12011422Abstract: Provided herein are novel synthetic compounds having the structure of formula (1), wherein X is a substituted or unsubstituted aromatic or heteroaromatic mono- or polycyclic ring system; and Y is substituted or unsubstituted C5-C10 alkyl or alkenyl group, or a pharmaceutically acceptable salt thereof. Also provided are pharmaceutical compositions. The compounds and pharmaceutical compositions are useful for inhibiting growth of a bacterium.Type: GrantFiled: May 27, 2022Date of Patent: June 18, 2024Assignee: McMaster UniversityInventors: Eric Brown, Omar M Elhalfawy, Nick Jentsch, Xiong Zhang, Jakob Magolan
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Publication number: 20240184423Abstract: A computer-implemented method for dynamic, data-driven consolidation of user interface interactions requesting roadside assistance. The method includes identifying a data objective requiring user data, accessing user data, and determining whether the user data satisfies a confidence threshold. Based at least in part on the confidence threshold determination, one of a first data objective representation and a second data objective representation is displayed. A request for roadside assistance—following satisfaction of the confidence threshold—is also issued.Type: ApplicationFiled: October 31, 2023Publication date: June 6, 2024Inventors: IVAN D. HALL, WILLIAM SIMONOVICH, MICHELLE DELYNN ADLER, JOSE GONZALEZ, ERIC SKAGGS, NICOLE LECLAIR, ANDREA FOSTER, JASON BECKMAN, JOSH SCHUMANN, KEVIN SCOTT LENZ, RITESH SARAF, ERIC BROWN
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Patent number: 11998235Abstract: An access assembly includes an instrument valve housing and a valve assembly disposed within the instrument valve housing. The instrument valve housing includes upper and lower housing sections. The valve assembly includes a centering mechanism, a seal assembly, and a guard assembly. The centering mechanism is configured to bias the valve assembly towards a generally centered position within the instrument valve housing. The centering mechanism includes a base seal member having an annular base and a flange portion. The flange portion includes an arcuate portion configured to adjustably engage first and second surfaces of the instrument valve housing in a sealing relation. The seal assembly is attachable to the centering mechanism. The seal assembly is configured to engage a surgical instrument inserted into the access assembly in a sealing relation. The guard assembly is attachable to the centering mechanism.Type: GrantFiled: August 9, 2022Date of Patent: June 4, 2024Assignee: Covidien LPInventors: Roy Pilletere, Garrett Ebersole, Eric Brown, Matthew Dinino, Justin Thomas, Jacob Baril, Nicolette LaPierre
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Publication number: 20240174746Abstract: The present disclosure is generally directed to compositions that include antibodies, e.g., monoclonal antibodies, antibody fragments, etc., that specifically bind a TMEM106B polypeptide, e.g., a mammalian TMEM106B or human TMEM106B, and use of such compositions in preventing, reducing risk, or treating an individual in need thereof.Type: ApplicationFiled: March 17, 2022Publication date: May 30, 2024Inventors: Eric BROWN, Angie Grace YEE, Tina SCHWABE, Herve RHINN, Arnon ROSENTHAL