Patents by Inventor Eric C. Sigillo

Eric C. Sigillo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rapid quantification assay involving concentrated and ligand-coated gold colloid
    Patent number: 8039272
    Abstract: A concentrated and ligand-coated gold colloid and a method of preparing it. Also disclosed is a rapid biomolecule quantification assay involving the use of the concentrated gold colloid and an apparatus for performing the assay.
    Type: Grant
    Filed: April 1, 2009
    Date of Patent: October 18, 2011
    Assignee: Nova Biomedical
    Inventors: Eric C. Sigillo, Jeffrey C. Chien, Mary C. Pomeroy, Catherine A. Saltalamacchia
  • RAPID QUANTIFICATION ASSAY INVOLVING CONCENTRATED AND LIGAND-COATED GOLD COLLOID
    Publication number: 20100255610
    Abstract: A concentrated and ligand-coated gold colloid and a method of preparing it. Also disclosed is a rapid biomolecule quantification assay involving the use of the concentrated gold colloid and an apparatus for performing the assay.
    Type: Application
    Filed: April 1, 2009
    Publication date: October 7, 2010
    Applicant: Nova Biomedical
    Inventors: Eric C. Sigillo, Jeffrey C. Chien, Mary C. Pomeroy, Catherine A. Saltalamacchia
  • Sol capture immunoassay kit and procedure
    Patent number: 6083760
    Abstract: An immunoassay procedure for detection of analytes in urine wherein an immunological reaction is conducted in an aqueous phase containing the urine and a filterable immunocomposite containing an inherently colored gold sol particle is formed if the assay is positive. The colored, gold sol particle containing immunocomposite is collected for direct visual observation on a filter element.
    Type: Grant
    Filed: December 30, 1992
    Date of Patent: July 4, 2000
    Assignee: Hygeia Sciences, Inc.
    Inventors: Charles C. Ditlow, L. Edward Cannon, Francis X. Cole, Gene A. Davis, Eric C. Sigillo, Alicia G. Danti
  • Sol capture immunoassay kit and procedure
    Patent number: 5202267
    Abstract: An immunoassay procedure for detection of analytes in urine wherein an immunological reaction is conducted in an aqueous phase containing the urine and a filterable immunocomposite containing an inherently colored gold sol particle is formed if the assay is positive. The colored, gold sol particle containing immunocomposite is collected for direct visual observation on a filter element.
    Type: Grant
    Filed: April 4, 1988
    Date of Patent: April 13, 1993
    Assignee: Hygeia Sciences, Inc.
    Inventors: Charles C. Ditlow, L. Edward Cannon, Francis X. Cole, Gene A. Davis, Eric C. Sigillo, Alicia G. Danti
  • Porous strip form assay device method
    Patent number: 5141850
    Abstract: An immunoassay method comprising applying an aqueous solution containing the analyte antigen to one end of a multi-zoned test strip device such that the solution moves along the strip by capillary action. The zones are arranged so that the solution (a) first contacts and reconstitutes dry, diffusible labelled component comprising colloidal gold conjugated to an antibody specific for said analyte antigen and then (b) contacts and reconstitutes dry, diffusible biotinylated second antibody specific for said analyte antigen such that a diffusible, dispersed sandwich reaction product forms. The reaction product diffuses along the strip with the solution and into a zone containing capture component consisting of a latex and avidin complex which avidin collects the reaction product by means of reaction with its biotin moiety. Thus, gold particles are collected and concentrated in the detection zone for visual determination.
    Type: Grant
    Filed: February 7, 1990
    Date of Patent: August 25, 1992
    Assignee: Hygeia Sciences, Inc.
    Inventors: Francis X. Cole, Eric C. Sigillo, Paul C. MacDonnell, Nancy J. Cicia