Patents by Inventor Eric Castro

Eric Castro has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230323341
    Abstract: Methods of reducing adapter-dimers in a sequencing library are provided according to aspects of the present disclosure, including: hybridizing excess 3? adapters to blocker oligonucleotides forming a hybridized complex, such that the excess 3? adapters are unavailable to form adapter-dimers, the hybridized complex including: a first blocker oligonucleotide 3? terminus adjacent to an adenylated nucleotide at the 5? terminus of a first unligated 3? adapter and a second blocker oligonucleotide 3? terminus adjacent to an adenylated nucleotide at the 5? terminus of a second unligated 3? adapter, wherein the first blocker oligonucleotide has a 5? portion complementary to and hybridized to the first unligated 3? adapter, the second blocker oligonucleotide has a 5? portion complementary to and hybridized to the second unligated 3? adapter, and the first blocker oligonucleotide has a 3? portion complementary to, and hybridized to, a 3? portion of the second blocker oligonucleotide.
    Type: Application
    Filed: March 24, 2023
    Publication date: October 12, 2023
    Inventors: Kevin D. Allen, Kerry Gunning, Allyson LeBas, Eric Castro
  • Patent number: D293455
    Type: Grant
    Filed: May 13, 1985
    Date of Patent: December 29, 1987
    Inventors: Eric Castro, Manuel Castro, Frank T. Silva