Abstract: A retractable step and side bar assembly that can be used for raised vehicles, such as trucks. The retractable step can be configured to provide for significant reach in a deployed position to allow for a user to enter the raised vehicle. Further, in the stowed position the retractable step can be located within the side bar, thereby providing a low profile as well as an enhanced aesthetic appearance.

Abstract: Technologies are disclosed for performing context-aware routing of traffic based on an application of a series of filters and/or selectors to determine an optimal group of interfaces for servicing traffic relating to a prefix. A traffic management control plane processes input data corresponding to aggregated telemetry data for a network by determining candidate groups of interfaces to service a network prefix and applies tunable filters and/or selectors to the candidate groups to determine a targeted group to use for servicing traffic corresponding to the prefix. The determined targeted group is mapped to the prefix in a mapping result, which is then provided to an actuator interface to control network devices to inject the new mapping into the network to control traffic according to the mapping.

Abstract: This invention relates to antibacterial compounds and compositions thereof. The invention also relates to the use of the compounds and compositions in methods of treating bacterial infections, particularly those bacterial infections including bacteria that exhibit antibiotic resistance. More specifically, the present invention provides a star shaped peptide polymer comprising a multifunctional core with a plurality of terminal arms extending therefrom, wherein the terminal arms are statistical or random peptide copolymers of at least a cationic amino acid residue and a hydrophobic amino acid residue.

Abstract: A chimeric or fusion protein for inducing an immune response to P. gingivalis, the protein comprising a first polypeptide linked to a second polypeptide, wherein: A) the first polypeptide comprises or consists of an amino acid sequence of the active site of an Arg- or Lys-gingipain of P. gingivalis, or a sequence that is at least 80% identical thereto; and B) the second polypeptide comprises or consists of an amino acid sequence of an adhesin domain of an Arg- or Lys-gingipain of P. gingivalis; and wherein the second polypeptide: a) comprises an amino acid sequence corresponding substantially to the full length of the DUF2436 domain of an Arg- or Lys-gingipain, or a sequence at least 80% identical thereto; and/or b) comprises one or more cysteine amino acid substitutions in the adhesin domain, compared to the naturally occurring Arg- or Lys-gingipain sequences in corresponding regions; and optionally comprises one or more amino acid motif substitutions in the adhesin domain for reducing multimerisation.

Abstract: The invention provides methods for the inhibition of Eosinophil Extracellular Trap (EET) formation. In particular, the invention provides antibodies or binding fragments thereof directed against citrulline-containing epitopes, for use in methods to inhibit or detect EET formation. The methods may be for the diagnosis, treatment or prevention of any disease or condition which includes an EET-associated pathology.

Abstract: A foldable wagon configurable in a use configuration and a folded configuration includes a frame that is foldable. The frame includes: a front frame assembly; a rear frame assembly; a center linkage disposed laterally between the front frame assembly and the rear frame assembly; an upper pivot bracket; a lower pivot bracket; and a middle pivot bracket disposed vertically between the upper pivot bracket and the lower pivot bracket, where the middle pivot bracket is slidable along the center linkage, where the front frame assembly and the rear frame assembly are pivotally connected to the upper pivot bracket, the lower pivot bracket, and the middle pivot bracket.

Abstract: The present invention relates to improved complexes of amorphous calcium phosphate and/or amorphous calcium fluoride phosphate stabilised by phosphopeptides/phosphoproteins by addition of stannous ions. These complexes have anticariogenic properties useful to protect tooth structures as they remineralize (repair) early stages of dental caries and have other dental/medical applications (including anti-calculus, anti-erosion/corrosion and anti-dentinal hypersensitivity). Methods of making the complexes of the invention and of treatment or prevention of various dental conditions including dental caries, dental calculus, dental erosion/corrosion and dental hypersensitivity are also provided.

Abstract: Disclosed herein are systems and methods that include a keypad that detects button presses using deflection sensing. The keypad may be a keypad of a camera such as an endoscopic camera head. A button press may be detected based on an amount of deflection of a material. The deflection of the material may be caused by force from a user's finger on a button of the keypad. The material may be located proximate to a sensor, which outputs a sensor signal indicating the amount of deflection of the material. Aspects of the disclosure comprise a controller that identifies an amount of deflection, compares the amount of deflection to a signal threshold, and determines whether a button has been pressed based on the comparison.

Abstract: A retractable step and side bar assembly that can be used for raised vehicles, such as trucks. The retractable step can be configured to provide for significant reach in a deployed position to allow for a user to enter the raised vehicle. Further, in the stowed position the retractable step can be located within the side bar, thereby providing a low profile as well as an enhanced aesthetic appearance.

Abstract: An electric roller skate system includes a pair of roller skates, where each of the pair of roller skates includes: a base configured to receive a foot of a rider, where the base comprises a front base and a rear base, where a distance between the front base and the rear base is adjustable; a front main body attached to the front base; a rear main body attached to the rear base; an ankle strap attached to the rear main body; two front wheels attached to a bottom of the front base; a rear wheel attached to a bottom of the rear base, where a cross-section of the rear wheel has a barrel shape; a battery; and an electric motor mechanically coupled to the rear wheel.

Abstract: A hoverboard includes: a main body including a left main body and a right main body, where the left main body and the right main body are independently tiltable around a center axis of the main body; a left wheel and a right wheel attached to the left main body and the right main body, respectively; a first fender and a second fender attached to a top surface of the main body proximate to the left wheel and the right wheel, respectively; a carrying handle attached to a front side of the main body; at least two speakers at a bottom surface of the main body; a wireless communication circuit configured to be paired with a user device for streaming digital media; and a stereo control panel at the bottom surface of the main body and having a suite of buttons for controlling playback of the digital media.

Abstract: A method of mounting a replacement tip section to an exposed end of a rotor blade includes removing an existing tip section from the rotor blade to create the exposed end of the rotor blade, installing the rotor blade having the exposed end onto a holding fixture, assembling the replacement tip section about the exposed end of the rotor blade, positioning a bonding fixture about the replacement tip section, and curing the replacement tip section to the exposed end of the rotor blade.

Abstract: The present invention relates to compositions for mineralizing a dental surface, in particular tooth enamel. Methods of mineralizing hypomineralized lesions (including subsurface lesions) in the tooth enamel caused by dental caries, dental corrosion and fluorosis are also provided. In particular, the invention relates to a method of mineralizing a dental surface or subsurface comprising contacting the dental surface or subsurface with a compound that is capable of increasing or maintaining the pH of a solution and a mineralizing agent.

Abstract: Described herein are light sources for illuminating a target for medical imaging, the light source comprising: a first light emitter package comprising a first light emitter that emits light having a first wavelength band and a second light emitter that emits light having a second wavelength band that is different than the first wavelength band; a second light emitter package comprising a third light emitter that emits light having a third wavelength band that is different than the first and second wavelength bands; and a controller for operating the light source in a first mode in which the first light emitter and the third light emitter are activated and the second light emitter is deactivated, and a second mode in which the first light emitter is deactivated and the second light emitter is activated.

Abstract: A light source for illuminating a target for medical imaging include a first light emitter package comprising a first light emitter that emits light having a first wavelength band and a second light emitter that emits light having a second wavelength band that is different than the first wavelength band; and a controller for operating the light source in a first mode in which the first light emitter is activated and the second light emitter is deactivated and a second mode in which the first light emitter is deactivated and the second light emitter is activated.

Abstract: The invention relates to discovering and clustering Internet protocol addresses. For example, the invention can include discovering an IPv6 address of an Internet-facing device on a network, where the IPv6 address is associated with a wide area network (WAN) media access control (MAC) address and a WiFi basic service set identifier (BSSID), identifying an associated BSSID in WiFi geolocation databases based on the WAN and WiFi BSSID, and geolocating the Internet-facing device by retrieving a location record in the WiFi geolocation databases for the associated BSSID.

Abstract: Techniques are described for determining a duration for a transition and alteration of the appearance of a user interface (UI) from a first UI state to a second UI state over the transition duration according to a timing function that specifies different rates of change in appearance over the course of the transition and is derived by adjusting a master timing function that is used to control a plurality of transitions in the UI to span the transition duration for the transition. A time value of an inflection point within the timing function is determined and the transition duration is divided into a first portion and a second portion so that the first portion extends from the beginning of the transition duration to the time value of the inflection point, and the second portion extends from the time value of the inflection point to the end of the transition duration.

Abstract: Provided are a blister package and a method of making thereof. The blister package includes a rupturable substrate; and a blister layer overlayed by the substrate, thereby making a cavity between the rupturable substate and the blister layer. The rupturable substrate at least partially forms an engraving or etching that reduces push through force required for dispensing a product stored inside the cavity for customer dispensing. The rupturable substate and the blister layer are made of the same or same class plastic or polymer thereby making the blister package recyclable.

Abstract: A retractable step and side bar assembly that can be used for raised vehicles, such as trucks. The retractable step can be configured to provide for significant reach in a deployed position to allow for a user to enter the raised vehicle. Further, in the stowed position the retractable step can be located within the side bar, thereby providing a low profile as well as an enhanced aesthetic appearance.