Abstract: The present disclosure relates to the field of biomedicine, and in particular, to an improved mutant of a respiratory syncytial virus (RSV) fusion (F) protein and uses thereof. The mutant can form a trimeric structure without introducing a heterologous trimerization domain. Meanwhile, through mutation designs such as releasing internal electrostatic repulsion, deleting the furin cleavage site, truncating the C-terminal domain, and introducing interchain disulfide bonds, the protein is stabilized in the pre-fusion conformation and exhibits enhanced stability. The mutant in the present disclosure is highly immunogenic when used as a vaccine or a vaccine component and can induce the production of a high level of neutralizing antibodies in the immunized animal, which can be used in the preparation of a vaccine for the prevention or treatment of RSV infection, and can also be used as a reagent for the detection of RSV.

Abstract: Data sets may be enhanced to create data stores. Request to create data stores may be received. As part of performing the request to create a data store, items stored in an extensible data format may be identified for machine learning enhancement. Machine learning models may be applied to generate additional data from data in the items. The additional data may be added to extend the items and store the extended items in a new data store.

Abstract: The present disclosure relates to the field of biomedicine, and in particular, to an improved mutant of a respiratory syncytial virus (RSV) fusion (F) protein and uses thereof. The mutant can form a trimeric structure without introducing a heterologous trimerization domain. Meanwhile, through mutation designs such as releasing internal electrostatic repulsion, deleting the furin cleavage site, truncating the C-terminal domain, and introducing interchain disulfide bonds, the protein is stabilized in the pre-fusion conformation and exhibits enhanced stability. The mutant in the present disclosure is highly immunogenic when used as a vaccine or a vaccine component and can induce the production of a high level of neutralizing antibodies in the immunized animal, which can be used in the preparation of a vaccine for the prevention or treatment of RSV infection, and can also be used as a reagent for the detection of RSV.

Abstract: An assembling method of a hidden interconnection arrangement of fence or railing is provided, wherein a downward force applied to a top wall of a lateral beam is able to press a bottom guider edge of a lower engaging arm downwards against a top edge of an engaging rail that generates a reaction force to enlarge a bottom opening of the lateral beam to allow the engaging rail to be engaged in an engaging recess and locked between an upper engaging arm and the lower engaging arm of the lateral beam while fasteners that fastened the engaging rails to a plurality of upright posts are hidden and concealed by the lateral beams and the pressing walls of the lateral beams press against flat surfaces of the upright posts respectively.

Abstract: An assembling method of a hidden interconnection arrangement of fence or railing is provided, wherein a downward force applied to a top wall of a lateral beam is able to press a bottom guider edge of a lower engaging arm downwards against a top edge of an engaging rail that generates a reaction force to enlarge a bottom opening of the lateral beam to allow the engaging rail to be engaged in an engaging recess and locked between an upper engaging arm and the lower engaging arm of the lateral beam while fasteners that fastened the engaging rails to a plurality of upright posts are hidden and concealed by the lateral beams and the pressing walls of the lateral beams press against flat surfaces of the upright posts respectively.

Abstract: Techniques and systems include predicting various health conditions using a photoplethysmography (PPG) signal or a video signal based on images of a patient's fingertip or other body portion captured using a mobile device. The video signal may be transformed into a pseudo PPG signal to measure blood volume changes in the patient's blood flow to derive data indicating a disease state or health-related characteristic, such as blood oxygen level, blood glucose level, heart rate variability, hemoglobin, respiration rate, or arrhythmia. Techniques involve real-time environment assessment and problematic issue detection, training an artificial intelligence (AI) model to measure signal quality so as to select high-quality signals from a range of signals, and domain adaption and transfer learning to make use of publicly available datasets.

Abstract: A positioning device for fence supplemented with pet guardrail comprises: an upper embedding slot and a lower embedding slot having face-to-face openings and extending axially being respectively formed on an opposite outside of the upper crossbar and the lower crossbar of the pet guardrail, for embedding the upper and lower ends of the straight rod and fixing the straight rod via the positioning peg from the inner side of the upper crossbar and the lower crossbar to avoid the exposure of the positioning peg and omitting the installation of the front cover plate on the front side of the upper crossbar and the lower crossbar, and moreover, the side cover installed and covered on the left and right ends of the upper crossbar and the side cover facing the end of side pole of the existing fence being an circular arc surface, thereby meeting the installation inclination angle of the existing fence. The configuration of the circular arc surface enables the side cover to maintain attached with the side pole.

Abstract: Techniques are described for an encoder or decoder to adaptively change coding based on a specific user's sensitivity to flickering, or flashing, or blockiness, or other visual artifacts. Alternatively, video may be pre-processed based on the user's sensitivity to suppress artifacts prior to encoding and/or post-processed to suppress artifacts after decoding.

Abstract: A combination structure of a straight bar and a cross bar of a guardrail is to comprise an embedding opening configured at a position where the cross bar provided for the straight bar to be inserted. A pair of buckle plates is configured inside the cross bar and on the two opposite sides of two sides of the embedding opening, the tail end of the buckle plate has a buckle part, and the buckle part is located within the bore diameter projection range of the embedding opening. The two opposite outer walls on the end part of the straight bar corresponding to the two buckle parts are configured with a horizontal snapping slot, and when the straight bar is inserted into the cross bar, the buckle part is embedded into the snapping slot. At the interior of the cross bar, a pair of stopping plates is extending from the inner wall of the cross bar away from the end of the embedding opening and at an adjacent side of the buckle part.

Abstract: A vertical post structure of a fence comprises an axial slot on at least one side of a post, and an axial notch at an end of the slot facing the post. An inner wall of the slot and the two sides near to the notch extend obliquely to form a clamping board, wherein a tail end of the clamping board has a buckle part. Each buckle part is positioned within the projection range of the notch, and a plate is fixed with a stop end of the post and corresponds to the slot. The buckle parts directly clip and buckle the end parts of the cross bars to fix them to the post, or the post can be assembled with the cross bars fixed inside the slot and to a base, and the plate prevents separation of the cross bars from the post.

Abstract: A combination structure of a straight bar and a cross bar of a guardrail is to comprise an embedding opening configured at a position where the cross bar provided for the straight bar to be inserted. The two corresponding inner walls inside the cross bar extend two the two sides of the embedding opening to form a buckle plate. The tail end of the buckle plate has a buckle part, and a distal end of the buckle part is located within a bore diameter projection range of the embedding opening. The extending direction of the buckle part is away from the embedding opening. Based on the above configuration, when the straight bar and the cross bar of the guardrail are assembled, the clamping force of two corresponding buckle plates enable the two corresponding buckle parts to strongly buckle the corresponding outer walls of two sides of the straight bar. The configuration is easily assembled and has tight stability and no residual gaps are left.

Abstract: Techniques and systems include predicting various health conditions using a photoplethysmography (PPG) signal or a video signal based on images of a patient's fingertip or other body portion captured using a mobile device. The video signal may be transformed into a pseudo PPG signal to measure blood volume changes in the patient's blood flow to derive data indicating a disease state or health-related characteristic, such as blood oxygen level, blood glucose level, heart rate variability, hemoglobin, respiration rate, or arrhythmia. Techniques involve real-time environment assessment and problematic issue detection, training an artificial intelligence (AI) model to measure signal quality so as to select high-quality signals from a range of signals, and domain adaption and transfer learning to make use of publicly available datasets.

Abstract: An apparatus, system and method are provided for an electrical stimulation. The apparatus generally includes at least two electrical stimulation units. Each electrical stimulation unit includes electrodes connected to the unit. The apparatus also includes a receiver configured for receiving the one or more control signals from a controller for controlling each of the electrical stimulation units to selectively apply a time-varying electric potential to the electrodes to provide an electrical stimulation to tissue in electrical contact with the electrodes. The apparatus generally includes a heating device.

Abstract: A method of automatically extracting information from electronic documents is discussed. The method includes a computer system receiving a plurality of electronic documents of a particular type that includes information arranged in a plurality of different formats. The method further includes, for each of a set of electronic documents, the computer system analyzes the electronic documents to identify tokens within the electronic documents, identifies a plurality of points-of-interest within the electronic documents, and matches points-of-interest based on distance between points-of-interest and a determination by a natural language processing model that the points-of-interest correspond. The method further includes generating revised versions of the electronic documents in which the matched points-of-interest are arranged in a universal format and storing the revised versions of the electronic documents.

Abstract: An apparatus, system and method are provided for a wireless electrical stimulation. The apparatus generally includes at least two electrical stimulation units. Each electrical stimulation unit includes electrodes connected to the unit. The apparatus also includes a receiver configured for receiving the one or more control signals from a remote controller for remotely, wirelessly controlling each of the electrical stimulation units to selectively apply a time-varying electric potential to the electrodes to provide an electrical stimulation to tissue in electrical contact with the electrodes. The apparatus generally includes a heating device.

Abstract: In some embodiments, a computer-implemented method includes obtaining a without-eyeglasses face scan of a subject, the without-eyeglasses face scan being a three-dimensional (3D) model of a face of the subject without eyeglasses; obtaining a with-eyeglasses face scan of the subject, the with-eyeglasses face scan being a 3D model of the subject with eyeglasses; and using the without-eyeglasses face scan and the with-eyeglasses face scan to place a 3D eyeglasses model on a face model of the subject. In some embodiments of the computer-implemented method, the 3D eyeglasses model is placed on the face model of the subject using frame placement information generated using the without-eyeglasses face scan and the with-eyeglasses face scan.

Abstract: An apparatus, system and method are provided for a wireless electrical stimulation. The apparatus generally includes at least two electrical stimulation units. Each electrical stimulation unit includes electrodes connected to the unit. The apparatus also includes a receiver configured for receiving the one or more control signals from a remote controller for remotely, wirelessly controlling each of the electrical stimulation units to selectively apply a time-varying electric potential to the electrodes to provide an electrical stimulation to tissue in electrical contact with the electrodes. The apparatus generally includes a heating device.

Abstract: An apparatus to detect a liquid in a wafer processing device is provided. The apparatus includes a first conductor proximate the wafer processing device. The apparatus includes a second conductor spaced apart from the first conductor and proximate the wafer processing device. The apparatus includes a liquid absorption material surrounding the first conductor and the second conductor. The apparatus includes a current source coupled to the first conductor. The apparatus includes a current detector coupled to at least one of the first conductor or the second conductor. The liquid absorption material establishes a conductive pathway between the first conductor and the second conductor when the liquid absorption material absorbs the liquid in the wafer processing device. A current is generated, by the current source, in at least one of the first conductor or the second conductor through the conductive pathway. The current detector detects the current.

Abstract: A method for computing centration measurements based on a digital photo, including receiving a digital photo of the face of a person wearing glasses, where the glasses have two lenses of equal size and a visible frame that surrounds each lens, where the wearer is facing the device that captured the photo, obtaining information about the frame size of the glasses, detecting facial landmarks for the face, extracting a bounding box for each of the two lenses, and computing a set of centration measurements that can be provided to a glasses manufacturer.

Abstract: A method implemented in a cloud gaming system having at least one server computer is provided, including the following operations: executing a game session of a video game, wherein the execution of the game session renders gameplay video and generates game state data; using a machine learning (ML) model to determine encoding parameter settings based on the game state data; applying, by an encoder, the encoding parameter settings for processing of the gameplay video to generate compressed gameplay video; streaming the compressed gameplay video over a network to a client device.