Patents by Inventor Eric D. Dowdy

Eric D. Dowdy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process and intermediates for preparing integrase inhibitors
    Patent number: 8877931
    Abstract: The invention provides synthetic processes and synthetic intermediates that can be used to prepare 4-oxoquinolone compounds having useful integrase inhibiting properties.
    Type: Grant
    Filed: August 1, 2013
    Date of Patent: November 4, 2014
    Assignee: Gilead Sciences, Inc.
    Inventors: Dominika Pcion, Carrie Tomasi, Mark Charles Whitcomb, Eric D. Dowdy, Wenyi Fu, Patricia MacLeod
  • PROCESS AND INTERMEDIATES FOR PREPARING INTEGRASE INHIBITORS
    Publication number: 20140039194
    Abstract: The invention provides synthetic processes and synthetic intermediates that can be used to prepare 4-oxoquinolone compounds having useful integrase inhibiting properties.
    Type: Application
    Filed: August 1, 2013
    Publication date: February 6, 2014
    Applicant: Gilead Sciences, Inc.
    Inventors: Dominika PCION, Carrie TOMASI, Mark Charles WHITCOMB, Eric D. DOWDY, Wenyi FU, Patricia MACLEOD
  • Crystalline pyridazine compound
    Patent number: 8569488
    Abstract: A crystalline compound of formula (1) and its salts and solvates are provided for the treatment or prophylaxis of hepatitis C virus infections Methods of making and formulating crystalline compound (1) are provided.
    Type: Grant
    Filed: December 23, 2011
    Date of Patent: October 29, 2013
    Assignees: Gilead Sciences, Inc., K.U. Leuven Research & Development
    Inventors: Eric D. Dowdy, Kenneth M. Kent, Norma J. Tom, Vahid Zia
  • Process for preparation of HIV protease inhibitors
    Patent number: 8431745
    Abstract: A process for the synthesis of bisfuran intermediates useful for preparing antiviral HIV protease inhibitor compounds is hereby disclosed.
    Type: Grant
    Filed: February 21, 2012
    Date of Patent: April 30, 2013
    Assignee: Gilead Sciences, Inc.
    Inventors: Kenneth R. Crawford, Eric D. Dowdy, Arnold Gutierrez, Richard P. Polniaszek, Richard Hung Chiu Yu
  • PROCESS FOR PREPARATION OF HIV PROTEASE INHBITORS
    Publication number: 20120258935
    Abstract: A process for the synthesis of bisfuran intermediates useful for preparing antiviral HIV protease inhibitor compounds is hereby disclosed
    Type: Application
    Filed: February 21, 2012
    Publication date: October 11, 2012
    Applicant: Gilead Sciences, Inc.
    Inventors: Kenneth R. Crawford, Eric D. Dowdy, Arnold Gutierrez, Richard P. Polniaszek, Richard Hung Chiu Yu
  • CRYSTALLINE PYRIDAZINE COMPOUND
    Publication number: 20120108601
    Abstract: A crystalline compound of formula (1) and its salts and solvates are provided for the treatment or prophylaxis of hepatitis C virus infections Methods of making and formulating crystalline compound (1) are provided.
    Type: Application
    Filed: December 23, 2011
    Publication date: May 3, 2012
    Applicants: Gilead Sciences, Inc., Gerhard Puerstinger, K.U. Leuven Research & Development
    Inventors: Eric D. Dowdy, Kenneth M. Kent, Norma J. Tom, Vahid Zia
  • Crystalline pyridazine compound
    Patent number: 8106054
    Abstract: A crystalline compound of formula (1) and its salts and solvates are provided for the treatment or prophylaxis of hepatitis C virus infections Methods of making and formulating crystalline compound (1) are provided.
    Type: Grant
    Filed: July 3, 2008
    Date of Patent: January 31, 2012
    Assignees: Gilead Sciences, Inc., K.U. Leuven Research & Development
    Inventors: Eric D. Dowdy, Kenneth M. Kent, Norma J. Tom, Vahid Zia
  • PROCESS FOR PREPARATION OF HIV PROTEASE INHIBITORS
    Publication number: 20110065631
    Abstract: A process for the synthesis of bisfuran intermediates of formula (0) useful for preparing antiviral HIV protease inhibitor compounds is hereby disclosed. Furthermore disclosed is a HIV protease inhibitor of formula (IV) as well as various intermediates thereof.
    Type: Application
    Filed: March 29, 2007
    Publication date: March 17, 2011
    Applicant: Gilead Sciences, Inc
    Inventors: Kenneth R. Crawford, Eric D. Dowdy, Arnold Gutierrez, Richard Polniaszek, Richard H. Yu
  • Crystalline pyridazine compound
    Publication number: 20090036460
    Abstract: A crystalline compound of formula (1) and its salts and solvates are provided for the treatment or prophylaxis of hepatitis C virus infections Methods of making and formulating crystalline compound (1) are provided.
    Type: Application
    Filed: July 3, 2008
    Publication date: February 5, 2009
    Applicants: Gilead Sciences, Inc., K.U. Leuven Research & Development, Gerhard Puerstinger
    Inventors: Eric D. Dowdy, Kenneth M. Kent, Norma J. Tom, Vahid Zia
  • Process for hydroxyazapirones
    Patent number: 6897309
    Abstract: This invention describes a process for preparing hydroxyazapirones of Formula I from azapirones of Formula II. The process comprises treating azapirones with a strong base, monitoring enolate formation of the azapirone by IR spectroscopy, and reacting the enolate with a source of molecular oxygen in the presence of a reductant. The process is suitable for large scale production of hydroxyazapirones.
    Type: Grant
    Filed: August 7, 2003
    Date of Patent: May 24, 2005
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jeffrey Depue, Atul S. Kotnis, Simon Leung, Eric D. Dowdy, Daniel J. Watson
  • Process for hydroxyazapirones
    Publication number: 20040067958
    Abstract: This invention describes a process for preparing hydroxyazapirones of Formula I from azapirones of Formula II. The process comprises treating azapirones with a strong base, monitoring enolate formation of the azapirone by IR spectroscopy, and reacting the enolate with a source of molecular oxygen in the presence of a reductant. The process is suitable for large scale production of hydroxyazapirones.
    Type: Application
    Filed: August 7, 2003
    Publication date: April 8, 2004
    Inventors: Jeffrey Depue, Atul S. Kotnis, Simon Leung, Eric D. Dowdy, Daniel J. Watson