Patents by Inventor Eric D. Strobel

Eric D. Strobel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Macrocycle derivatives useful as inhibitors of ?-secretase (BACE)
    Patent number: 7932261
    Abstract: The present invention is directed to macrocycle derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of ?-secretase, also known as ?-site cleaving enzyme and BACE, BACE1, Asp2 and memapsin2.
    Type: Grant
    Filed: February 6, 2007
    Date of Patent: April 26, 2011
    Assignee: Janssen Pharmaceutica NV
    Inventors: Ellen W. Baxter, François P. Bischoff, Hans De Winter, Chih Yung Ho, Yifang Huang, Michael H. Parker, Allen B. Reitz, Charles H. Reynolds, Eric D. Strobel
  • N-substituted tricyclic 1-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders
    Patent number: 7795440
    Abstract: The invention is directed to N-substituted tricyclic 3-AMINOPYRAZOLE derivatives, which are useful as inhibitors of platelet-derived growth factor receptor (PDGF-R) kinase, and methods for the preparation of said derivatives. The present invention is further directed to pharmaceutical compositions comprising the compounds of the present invention and to methods for treating conditions such as tumors and other cell proliferative disorders.
    Type: Grant
    Filed: January 25, 2007
    Date of Patent: September 14, 2010
    Assignee: Janssen Pharmaceutica NV
    Inventors: Chih Yung Ho, Bengt Anders Brunmark, Stuart Emanuel, Robert A. Galemmo, Jr., Dana L. Johnson, Donald W. Ludovici, Umar Maharoof, Jay M. Mei, Jan L. Sechler, Eric D. Strobel, Robert W. Tuman, Hwa Kwo Yen
  • 2-amino-3,4-dihydro-pyrido[3,4-d]pyrimidine derivatives useful as inhibitors of ?-secretase (BACE)
    Patent number: 7531545
    Abstract: The present invention is directed to novel 2-amino-3,4-dihydro-pyrido[3,4-d]pyrimidine derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of ?-secretase, also known as ?-site cleaving enzyme and BACE, BACE1, Asp2 and memapsin2.
    Type: Grant
    Filed: October 25, 2006
    Date of Patent: May 12, 2009
    Assignee: Janssen Pharmaceutica, N.V.
    Inventors: Ellen E. Baxter, Christopher John Creighton, Yifang Huang, Chi Luo, Michael H. Parker, Allen B. Reitz, Charles H. Reynolds, Tina Morgan Ross, Eric D. Strobel, Brett A. Tounge
  • N-substituted tricyclic 3-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders
    Patent number: 7196110
    Abstract: The invention is directed to N-substituted tricyclic 3-AMINOPYRAZOLE derivatives, which are useful as inhibitors of platelet-derived growth factor receptor (PDGF-R) kinase, and methods for the preparation of said derivatives. The present invention is further directed to pharmaceutical compositions comprising the compounds of the present invention and to methods for treating conditions such as tumors and other cell proliferative disorders.
    Type: Grant
    Filed: May 14, 2003
    Date of Patent: March 27, 2007
    Assignee: Janssen Phamaceutica N.V.
    Inventors: Chih Yung Ho, Bengt Anders Brunmark, Stuart Emanuel, Robert A. Galemmo, Jr., Dana L. Johnson, Donald W. Ludovici, Umar Maharoof, Jay M. Mei, Jan L. Sechler, Eric D. Strobel, Robert W. Tuman, Hwa Kwo Yen
  • N-substituted tricyclic 3-aminopyrazoles as inhibitors for the treatment of cell proliferative disorders
    Publication number: 20040082639
    Abstract: The invention is directed to N-substituted tricyclic 3-AMINOPYRAZOLE derivatives, which are useful as inhibitors of platelet-derived growth factor receptor (PDGF-R) kinase, and methods for the preparation of said derivatives. The present invention is further directed to pharmaceutical compositions comprising the compounds of the present invention and to methods for treating conditions such as tumors and other cell proliferative disorders.
    Type: Application
    Filed: May 14, 2003
    Publication date: April 29, 2004
    Inventors: Chih Yung Ho, Bengt Anders Brunmark, Stuart Emanuel, Robert A. Galemmo, Dana L. Johnson, Donald W. Ludovici, Umar Maharoof, Jay M. Mei, Jan L. Sechler, Eric D. Strobel, Robert W. Tuman, Hwa Kwo Yen