Abstract: The present invention relates to methods and compositions for treating autoimmune or inflammatory disease characterised by an aberrant or inappropriate immune response to one or more of Ro60 protein; MPO protein; and Smith protein.

Abstract: A catheter interface protection device can include a shield. The shield can include an open bottom, a transparent upper surface, sidewalls, and a cavity at least partially defined by the bottom, the upper surface, and the sidewalls. The device can include a vent. The device can include a clip, a tether, and a latch. A non-therapeutic method of protecting a catheter interface can include extending a catheter in the subject through a slot in a catheter interface protection device, wrapping the catheter at least partially around a clip of the catheter interface protection device, and securing a latch of the catheter interface protection device around the clip. A device for positioning a subject in a prone position can include a padded area including an opening configured to accommodate a catheter interface protection device.

Abstract: A method of forming a balanced rotor blade assembly includes measuring a weight of a plurality of sub-components of the rotor blade assembly excluding a core. A configuration of a core of the rotor blade assembly is determined. In combination, the core and the plurality of sub-components achieve a target weight distribution and moment. The core is then fabricated and assembled with the plurality of sub-components to form a rotor blade sub-assembly.

Abstract: Systems, apparatus, methods and computer-readable storage media facilitating trusted pairing between an implantable medical device (IMD) and an external device are provided. In one embodiment, an IMD includes a housing configured to be implanted within a patient, a memory and circuitry within the housing and a processor that executes executable components stored in the memory.

Abstract: Traditionally, meetings are widely utilized in business and personal communications, whether in-person and/or virtual. Organizing such meetings typically involves multiple exchanges of content and messages between users before, during, and after the meeting. In some cases, meetings may occur impromptu and may result in inefficient and unproductive collaboration. A collaboration object configured to enable users to dynamically collaborate before, during, and after a meeting is provided. In aspects, the collaboration object links content generated before, during, and after the meeting in a single location and provides functionality for concurrent multi-user interaction and synchronization of the content across applications. The collaboration object may be available from a variety of application platforms, enabling and persisting real-time editing and collaboration before, during and after the meeting.

Abstract: A foundation for a bed system can include a foundation structure having a head, a foot, a first side, and a second side. An air pump configured for supplying air to and inflating at least one mattress air chamber can be housed within the foundation structure proximate the foot of the foundation structure. A control box and a central power hub can be housed within the foundation structure. The central power hub can be electrically connected to and configured to deliver electrical power to each of the air pump, the control box, and one or more additional electrical components. The foundation can optionally integrate other components into the foundation.

Abstract: The present disclosure provides a method of treating a human subject suffering from a retinal disorder, the method comprising administering to the eye of the subject via intravitreal injection a composition comprising a compound of formula (I) as described herein.

Abstract: Systems, methods and computer-readable storage media can be used to debug content items. One example method includes presenting, by a mobile application executing on a mobile device, a first application interface. The example method further includes detecting, by the mobile device, a predetermined user action. The example method further includes, in response to detecting the predetermined user action, generating debugging information from content event logs, wherein the content event logs are associated with content item slots in which content items are presented in the mobile application and presenting, by a debugging interface, the debugging information.

Abstract: One variation of a system for detecting inputs at a computing device includes: a substrate including a top layer, a bottom layer defining an array of support locations, and electrode pairs proximal the support locations; a touch sensor surface arranged over the top layer of the substrate; a set of spacers, each arranged over an electrode pair at a support location on the bottom layer of the substrate and including a force-sensitive material exhibiting variations in local bulk resistance responsive to variations in applied force; an array of spring elements coupled to the set of spacers, configured to support the substrate on a chassis, and configured to yield to displacement of the substrate downward toward the chassis responsive to forces applied to the touch sensor surface; and a controller configured to interpret forces of inputs on the touch sensor surface based on resistance values of the electrode pairs.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for adjusting an adjustable textile based on sensor data. The methods, systems, and apparatus include actions of receiving sensor data from one or more sensors installed at a property, generating an analysis result by analyzing the sensor data, and determining, based on the analysis result, an action that adjusts an inflation level of an adjustable textile at the property.

Abstract: In an embodiment, the present invention provides a compound of the formula: or a pharmaceutically acceptable salt thereof, and methods of using this compound for treating type II diabetes mellitus.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for reserving airspace for UAV operations. In some implementations, a flight planning system can reserve and allocate airspace for unmanned aerial vehicle (UAV) operations. For example, a UAV operator device can submit a flight plan to the flight planning system. The flight planning system can submit a flight authorization request to an airspace management system to reserve airspace necessary for the flight plan. The flight planning system can receive approval and/or a reservation of the airspace for the flight plan from the airspace management system, generate a flight data package, and send the flight data package to the operator's device.

Abstract: In variants, a fleet management method can include: determining information about a device; and sending information to the device, including authentication credentials, wherein the device can authenticate itself with other devices within the fleet using the authentication credentials. The fleet management system can function to scalably manage the operation and permissioning of one or more fleets of devices.

Abstract: A wastewater treatment system comprising a basin, an N2O sensor, and an organic carbon source. The basin is configured to subject wastewater to an activated sludge-based biological treatment wherein nitrogen is removed from the wastewater. The N2O sensor is positioned in the basin and configured to produce an N2O detection in the biological treatment. The organic carbon source is fluidly connected to the basin. The wastewater treatment system is configured to dose organic carbon from the organic carbon source to the biological treatment based on the N2O detection so that the wastewater treatment system controls an N2O level of the biological treatment via the organic carbon.

Abstract: The present disclosure relates to high fiber-containing ready-to-eat food pieces, compositions including such food pieces, and methods of making such food pieces. The food pieces include at least 35% and up to 55% by dry weight total fiber, an insoluble fiber content of at least 28% to about 40% by dry weight, and a soluble fiber content of about 7% to about 15% by dry weight. The food pieces include bran, optionally a second insoluble fiber source, psyllium husk, and a starch ingredient, with a moisture content of up to 4% by weight. Compositions containing such high fiber food pieces and methods of making them are also described.

Abstract: Methods, systems, and apparatus, including computer programs encoded on a storage device, are disclosed. A system performs operations including receiving sensor data from a sensor of a property monitored by a monitoring system, and based on the sensor data, determining a first event and a second event that have occurred at the property. The operations include determining that the monitoring system is not able to communicate with an outside network, and classifying the first event as a high priority event and the second event as a low priority event. The operations include determining that a mobile device is able to receive data from the monitoring system; and providing, to the mobile device, data indicating the first event and an instruction to transmit the data indicating the first event to a server upon the mobile device being able to communicate with the outside network.

Abstract: A system for assembling a tower for a wind generator having a succession of subsections (Si). The system including: a plurality of lifting legs, a lifting structure vertically movable on the lifting legs, the lifting structure including a rigid lifting frame for holding the tower under assembly, the lifting frame including load transfer members and the lifting structure including self-climbing mechanisms interacting between the load transfer members and the lifting legs for elevating or lowering the lifting structure, and at least a first set of gripping arms movable relative to the lifting frame between a retracted configuration and a gripping configuration.

Abstract: An automatic tattoo apparatus can be used to robotically apply tattoos. A customer can shop on an online tattoo marketplace to select designs created by various artists located anywhere. The online tattoo marketplace can process and manage payments, artist and/or customer profiles, bookings, tattoo design uploads, browsing and design selection, design changes, and/or perform other actions. The automatic tattoo device can apply tattoos precisely, quickly, and may with reduced pain. The tattoo apparatus can apply a wide range of different types of tattoos, including but not limited to micro tattoos, dotwork, blackwork tattoos, realism tattoos, fine-line tattoos, etc.

Abstract: One variation of a system includes a substrate including: a first layer including a first spiral trace coiled in a first direction; a second layer arranged below the first layer and including a second spiral trace coiled in a second direction and cooperating with the first spiral trace to form a multi-layer inductor; and a sensor layer including an array of drive and sense electrode pairs. The system also includes: a cover layer arranged over the substrate and defining a touch sensor surface; and a first magnetic element arranged below the substrate and defining a first polarity facing the multi-layer inductor. The system further includes a controller configured to drive an oscillating voltage across the multi-layer inductor to oscillate the substrate in response to detecting an input on the touch sensor surface based on electrical values from the set of drive and sense electrode pairs.