Patents by Inventor Eric Day
Eric Day has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11959838Abstract: The disclosure generally relates to the preparation of representative samples from clinical samples, e.g., tumors (whole or in part), lymph nodes, metastases, cysts, polyps, or a combination or portion thereof, using mechanical and/or biochemical dissociation methods to homogenize intact samples or large portions thereof. The resulting homogenate provides the ability to obtain a correct representative sample despite spatial heterogeneity within the sample, increasing detection likelihood of low prevalence subclones, and is suitable for use in various diagnostic assays as well as the production of therapeutics, especially “personalized” anti-tumor vaccines or immune cell based therapies.Type: GrantFiled: April 27, 2018Date of Patent: April 16, 2024Assignee: Ventana Medical Systems, Inc.Inventors: Nelson Alexander, Aoune Barhoumi, Melinda Day, Lisa Gallegos, Katherine Leith, Samantha Rajkovich, Esteban Roberts, Stacey Stanislaw, Eric Walk
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Patent number: 11828532Abstract: A method and apparatus for transferring a first liquid removed from an outlet of a first distillation column to an inlet of a second distillation column is provided. The second distillation column operates at a higher pressure than the first distillation column, and the inlet of the second distillation column is at higher elevation as compared to the outlet of the first distillation column. The method advantageously transfers the first liquid from the outlet to the inlet by mixing with a sufficient amount of a lower density second liquid that results in a mixed liquid having a reduced density as compared to the first liquid.Type: GrantFiled: December 31, 2020Date of Patent: November 28, 2023Assignee: L'Air Liquide Societe Anonyme Pour L'Etude Et L'Exploitation Des Procedes Georges ClaudeInventor: Eric Day
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Publication number: 20230360660Abstract: Disclosed are methods and systems for decoding immersive audio content encoded by an adaptive number of scene elements for channels, audio objects, higher-order ambisonics (HOA), and/or other sound field representations. The decoded audio is rendered to the speaker configuration of a playback device. For bit streams that represent audio scenes with a different mixture of channels, objects, and/or HOA in consecutive frames, fade-in of the new frame and fade-out of the old frame may be performed. Crossfading between consecutive frames happen in the speaker layout after rendering, in the spatially decoded content type before rendering, or between the transport channels as the output of the baseline decoder but before spatial decoding and rendering. Crossfading may use an immediate fade-in and fade-out frame (IFFF) for the transition frame or may use an overlap-add synthesis technique such as time-domain aliasing cancellation (TDAC) of MDCT.Type: ApplicationFiled: September 10, 2021Publication date: November 9, 2023Inventors: Moo Young KIM, Dipanjan SEN, Eric ALLAMANCHE, J. Kevin Calhoun, Frank BAUMGARTE, Sina ZAMANI, Eric DAY
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Patent number: 11709018Abstract: A cryogenic air separation setup in a cold box, wherein gaseous oxygen under elevated pressure is produced through hydraulic force caused by the geodetic distance between where liquid oxygen is drawn from the distillation column and where liquid oxygen is vaporized to form gaseous oxygen, such as in an auxiliary evaporator. To increase the vertical distance between the above-mentioned two location, the components are arranged directly below one another in the following sequence: the lower-pressure column, the main condenser evaporator, the higher-pressure column, the subcooler, the main heat exchanger and the auxiliary evaporator). In particular, the main heat-exchanger is positioned with the cold-end on the top to optimize piping expenditure.Type: GrantFiled: December 25, 2017Date of Patent: July 25, 2023Assignee: L'Air Liquide, Societe Anonyme Pour L'Etude Et L'Expoitation Des Procedes Georges ClaudeInventors: Alain Briglia, Remy Kurtz, Eric Day, Huali Xie, Baptiste Fara
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Patent number: 11612850Abstract: Disclosed in the present invention are a pressure equalizing system for air separation purification, and a control method. The system comprises: a first air main pipe; a pressurizing gas pipeline, which is connected to the first air main pipe and used for receiving a pressurizing gas and delivering same to the first air main pipe; and a control valve, located on the pressurizing gas pipeline, and having a degree of opening regulated by the flow regulator, thereby regulating an air intake amount of the pressurizing gas pipeline.Type: GrantFiled: October 28, 2020Date of Patent: March 28, 2023Assignee: L'Air Liquide, Societe Anonyme Por L'Etude Et L'Exploitation Des Procedes Georges ClaudeInventor: Eric Day
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Publication number: 20230044196Abstract: A device for preparing high-purity hydrogen and/or oxygen by electrolyzing water, including an electrolyzer and a degasser for degassing desalted water. The degasser is located at the upstream of the electrolyzer. After desalted water is heated and degassed in the degasser, the content of gaseous impurities, particularly argon, can be reduced to several ppb (weight ratio). The hydrogen and oxygen generated after the desalted and degassed water is electrolyzed in the electrolyzer also contain an extremely small amount of argon, so that the requirements in semiconductor industry are met. Also involved is a method of preparing high-purity hydrogen and/or oxygen by using the device.Type: ApplicationFiled: December 21, 2020Publication date: February 9, 2023Inventors: Alain BRIGLIA, Eric DAY, Michael WAKIM
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Publication number: 20220205715Abstract: A method and apparatus for transferring a first liquid removed from an outlet of a first distillation column to an inlet of a second distillation column is provided. The second distillation column operates at a higher pressure than the first distillation column, and the inlet of the second distillation column is at higher elevation as compared to the outlet of the first distillation column. The method advantageously transfers the first liquid from the outlet to the inlet by mixing with a sufficient amount of a lower density second liquid that results in a mixed liquid having a reduced density as compared to the first liquid.Type: ApplicationFiled: December 31, 2020Publication date: June 30, 2022Applicant: L'Air Liquide, Societe Anonyme pour l'Etude et l'Exploitation des Procedes Georges ClaudeInventor: Eric DAY
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Patent number: 11326943Abstract: A data collection device includes a housing and a data collection unit located in the housing. A power unit is located in the housing and is operably connected to the data unit to provide power for operation of the data unit. An irradiation sensor is located at the data collection device to detect exposure of the data collection device to irradiation. An irradiation sensor includes a thermal energy absorbing material and a thermal energy sensitive material in thermal communication with the thermal energy absorbing material. The thermal energy sensitive material is characterized by a change in color when exposed to a selected degree of thermal energy due to irradiation.Type: GrantFiled: February 15, 2017Date of Patent: May 10, 2022Assignee: CARRIER CORPORATIONInventors: Richard Desmarais, Eric Day
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Publication number: 20220128301Abstract: A method and apparatus for producing a high-pressure gas from an air separation unit is provided, in which the method includes the steps of introducing a cold air feed into a distillation column system under conditions effective for separating the cold air feed into a first air gas and a second air gas; withdrawing the first and second air gases from the distillation column system and warming said first and second air gases in a main heat exchanger, wherein the first air gas is withdrawn from the distillation column system at a medium pressure; splitting the first air gas into a first fraction and a second fraction; expanding the first fraction in a turbine; and compressing the second fraction in a booster to a pressure that is higher than the medium pressure, wherein the booster is powered by the turbineType: ApplicationFiled: October 13, 2021Publication date: April 28, 2022Applicant: L'Air Liquide, Societe Anonyme pour l'Etude et l?Exploitation des Procedes Georges ClaudeInventors: Jianwei CAO, Lin XU, Eric DAY, Baptiste FARA
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Publication number: 20220074657Abstract: In a process for starting up an air separation unit, which is at a temperature of above 0° C., the air separation unit comprising a main air compressor for compressing the feed air, a booster driven by a turbine and a venting conduit connected downstream of the booster and upstream of the main heat exchanger wherein in order to start up the air separation unit, once the turbine is operating at said given speed, the venting conduit is opened to send at least part of the air compressed in the booster from the booster outlet to the atmosphere.Type: ApplicationFiled: December 19, 2018Publication date: March 10, 2022Applicant: L'Air Liquide, Societe Anonyme pour l'Etude et l'Exploitation des Procedes Georges ClaudeInventors: Eric DAY, Fei GAO, Huali XIE
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Publication number: 20210404740Abstract: A plate fin heat exchanger assembly (S) for a cryogenic air separation unit, comprising: a heat exchanger having at least two cryogenic liquid inlets (B,C) at least two cryogenic liquid outlets (B,C), at least one nitrogen-rich stream inlet (D) at a first end of the heat exchanger and at least one nitrogen-rich stream outlet at a second end of the heat exchanger, the heat exchanger configured to receive a flow of at least one nitrogen-rich stream (WN,LPGAN) of the air separation unit at the at least one nitrogen-rich stream inlet and separate flows of at least two cryogenic liquids (LOX,LIN,LR) at the at least two cryogenic liquid inlets; wherein the inlet of the first of the cryogenic liquids is closer to the first end than the outlet of the second of the cryogenic liquids.Type: ApplicationFiled: October 26, 2018Publication date: December 30, 2021Applicant: L'Air Liquide, Societe Anonyme pour l'Etude et l'Exploitation des Procedes Georges ClaudeInventors: Jian-Wei CAO, Eric DAY, Sophie LAZZARINI
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Publication number: 20210287416Abstract: An exemplary character interaction system located at a first site receives character behavior data representative of captured behavior of a real-world performer located at a second site. Based on the character behavior data, the system presents, to an interactive user at the first site, a representation of a virtual character avatar that performs, in real-time synchrony with the real-world performer at the second site, the captured behavior of the real-world performer. During this presentation of the virtual character avatar, the system provides user video data representative of captured behavior of the interactive user for presentation to the real-world performer to allow the real-world performer to interact in real time with the interactive user via the virtual character avatar. The system also generates an augmented representation of an interaction between the virtual character avatar and the interactive user for presentation to a non-interactive observer.Type: ApplicationFiled: March 13, 2020Publication date: September 16, 2021Inventors: Colleen Elizabeth O'Hagan, Benjamin Michael Roffee, Ian Nelson, Patrick Ian Moss, Alastair D Macleod, Kevin Gorgonia, Adnan Nabeel Ghani, Eric Day
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Patent number: 11100695Abstract: An exemplary character interaction system located at a first site receives character behavior data representative of captured behavior of a real-world performer located at a second site. Based on the character behavior data, the system presents, to an interactive user at the first site, a representation of a virtual character avatar that performs, in real-time synchrony with the real-world performer at the second site, the captured behavior of the real-world performer. During this presentation of the virtual character avatar, the system provides user video data representative of captured behavior of the interactive user for presentation to the real-world performer to allow the real-world performer to interact in real time with the interactive user via the virtual character avatar. The system also generates an augmented representation of an interaction between the virtual character avatar and the interactive user for presentation to a non-interactive observer.Type: GrantFiled: March 13, 2020Date of Patent: August 24, 2021Assignee: Verizon Patent and Licensing Inc.Inventors: Colleen Elizabeth O'Hagan, Benjamin Michael Roffee, Ian Nelson, Patrick Ian Moss, Alastair D Macleod, Kevin Gorgonia, Adnan Nabeel Ghani, Eric Day
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Publication number: 20210207995Abstract: A data collection device includes a housing and a data collection unit located in the housing. A power unit is located in the housing and is operably connected to the data unit to provide power for operation of the data unit. An irradiation sensor is located at the data collection device to detect exposure of the data collection device to irradiation. An irradiation sensor includes a thermal energy absorbing material and a thermal energy sensitive material in thermal communication with the thermal energy absorbing material. The thermal energy sensitive material is characterized by a change in color when exposed to a selected degree of thermal energy due to irradiation.Type: ApplicationFiled: February 15, 2017Publication date: July 8, 2021Inventors: Richard Desmarais, Eric Day
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Publication number: 20210138387Abstract: Disclosed in the present invention are a pressure equalizing system for air separation purification, and a control method. The system comprises: a first air main pipe; a pressurizing gas pipeline, which is connected to the first air main pipe and used for receiving a pressurizing gas and delivering same to the first air main pipe; and a control valve, located on the pressurizing gas pipeline, and having a degree of opening regulated by the flow regulator, thereby regulating an air intake amount of the pressurizing gas pipeline.Type: ApplicationFiled: October 28, 2020Publication date: May 13, 2021Applicant: L'Air Liquide, Societe Anonyme pour l'Etude et l'Exploitation des Procedes Georges ClaudeInventor: Eric DAY
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Publication number: 20210142273Abstract: A method of monitoring a cargo area includes receiving sound data at a sound sensor situated in a cargo area, analyzing the sound data, and reporting a condition of the cargo area based on the analysis. A monitoring system for a cargo area is also disclosed.Type: ApplicationFiled: November 9, 2020Publication date: May 13, 2021Inventors: Peter M. Nunes, Robin L. Wald, Eric Day, Peter Borenstein, Thomas Shoemaker, Natalia Andreyeva
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Publication number: 20210063085Abstract: A cryogenic air separation setup in a cold box, wherein gaseous oxygen under elevated pressure is produced through hydraulic force caused by the geodetic distance between where liquid oxygen is drawn from the distillation column and where liquid oxygen is vaporized to form gaseous oxygen, such as in an auxiliary evaporator. To increase the vertical distance between the above-mentioned two location, the components are arranged directly below one another in the following sequence: the lower-pressure column, the main condenser evaporator, the higher-pressure column, the subcooler, the main heat exchanger and the auxiliary evaporator).Type: ApplicationFiled: December 25, 2017Publication date: March 4, 2021Applicant: L'Air Liquide, Societe Anonyme pour l'Etude et l?Exploitation des Procedes Georges ClaudeInventors: Alain BRIGLIA, Remy KURTZ, Eric DAY, Huali XIE, Baptiste FARA
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Publication number: 20200355429Abstract: Provided are a method and apparatus for producing nitrogen and oxygen by means of cryogenic distillation of air. Nitrogen products are extracted only from the top of a tower. If a customer needs nitrogen with lower pressure, part of pure nitrogen that is partially located at a first nitrogen product pressure is reheated in a main heat exchanger, then decompressed to a second nitrogen product pressure by means of a nitrogen expander, further reheated by means of the main heat exchanger, and output as a low-pressure nitrogen product. The nitrogen expander can be braked by an expander booster for compressing air. By means of the method, nitrogen with different pressures can be suitably produced, and the energy consumption for producing the pressurized air can be reduced by utilizing the expansion work of nitrogen.Type: ApplicationFiled: November 29, 2017Publication date: November 12, 2020Applicant: L'Air Liquide, Societe Anonyme pour l'Etude et l'Exploitation des Procedes Georges ClaudeInventors: Bowei ZHAO, Alain BRIGLIA, Fengjie XUE, Eric DAY
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Patent number: 9567392Abstract: In one aspect, the disclosure provides neutralizing antibodies against JCV and methods for the treatment of PML. In some embodiments, aspects of the invention relate to an isolated JC-vims neutralizing monoclonal antibody against JCV capsid protein VPI (JCV-VP1). In some embodiments, the antibody suppresses infectivity of the JC-vims. In some embodiments, the antibody binds the sialic acid binding pocket of JCV-VP1.Type: GrantFiled: March 15, 2013Date of Patent: February 14, 2017Assignee: Biogen MA Inc.Inventors: Kenneth Simon, Thomas Cameron, Deping Wang, Joseph Arndt, Mia Rushe, Justin Caravella, Eric Day
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Publication number: 20150050271Abstract: In one aspect, the disclosure provides neutralizing antibodies against JCV and methods for the treatment of PML. In some embodiments, aspects of the invention relate to an isolated JC-vims neutralizing monoclonal antibody against JCV capsid protein VPI (JCV-VP1). In some embodiments, the antibody suppresses infectivity of the JC-vims. In some embodiments, the antibody binds the sialic acid binding pocket of JCV-VP1.Type: ApplicationFiled: March 15, 2013Publication date: February 19, 2015Applicant: Biogen Idec MA Inc.Inventors: Kenneth Simon, Thomas Cameron, Deping Wang, Joseph Arndt, Mia Rushe, Justin Caravella, Eric Day