Patents by Inventor Eric De Grandpre

Eric De Grandpre has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Neuroprotective composition and uses thereof
    Patent number: 6858646
    Abstract: A neuroprotective composition for protecting neuronal cells against oxidative stress and methods for using and preparing the same. More particularly, the neuroprotective composition of the invention comprises a mixture of pyruvate, antioxidant, and lipid(s) such as fatty acids. The neuroprotective composition could be used for the treatment of brain trauma, brain or cerebrovascular ischemia, neurodegenerative diseases, poisoning of neuronal cells, the diminution of drugs side effects and for preservation of neuronal grafts.
    Type: Grant
    Filed: November 5, 2001
    Date of Patent: February 22, 2005
    Assignee: Universite du Quebec a Montreal
    Inventors: Joanne Paquin, Mircea-Alexandru Mateescu, Éric De Grandpré
  • Neuroprotective composition and uses thereof
    Publication number: 20040235947
    Abstract: A neuroprotective composition for protecting neuronal cells against oxidative stress and methods for using and preparing the same. More particularly, the neuroprotective composition of the invention comprises a mixture of pyruvate, antioxidant, and lipid(s) such as fatty acids. The neuroprotective composition could be used for the treatment of brain trauma, brain or cerebrovascular ischemia, neurodegenerative diseases, poisoning of neuronal cells, the diminution of drugs side effects and for preservation of neuronal grafts.
    Type: Application
    Filed: May 18, 2004
    Publication date: November 25, 2004
    Inventors: Joanne Paquin, Mircea-Alexandru Mateescu, Eric De Grandpre
  • Ceruloplasmin and an antioxidant composition comprising the same and their uses as neuroprotective agent
    Patent number: 6780842
    Abstract: A neuroprotective composition for protecting neuronal cells against oxidative stress and methods for using and preparing the same. More particularly, the neuroprotective composition of the invention comprises a therapeutically effective amount of ceruloplasmin or a functional derivative thereof. The neuroprotective composition is characterized in that it protects neuronal cells from reactive oxygen species such as •O2− and •OH. In a preferred embodiment, the neuroprotective composition further comprises an antioxidant consisting of catalase or of an amphiphilic physiological antioxidative solution comprising a mixture of pyruvate, antioxidant, and lipid(s) such as fatty acids. The neuroprotective composition could be used for the treatment of brain trauma, brain or cerebrovascular ischemia, neurodegenerative diseases, poisoning of neuronal cells, the diminution of drugs side effects and for preservation of neuronal grafts.
    Type: Grant
    Filed: November 5, 2001
    Date of Patent: August 24, 2004
    Assignee: Warner-Lambert Company LLC
    Inventors: Joanne Paquin, Mircea-Alexandru Mateescu, Éric De Grandpré
  • Neuroprotective composition and uses thereof
    Publication number: 20020128316
    Abstract: A neuroprotective composition for protecting neuronal cells against oxidative stress and methods for using and preparing the same. More particularly, the neuroprotective composition of the invention comprises a mixture of pyruvate, antioxidant, and lipid(s) such as fatty acids. The neuroprotective composition could be used for the treatment of brain trauma, brain or cerebrovascular ischemia, neurodegenerative diseases, poisoning of neuronal cells, the diminution of drugs side effects and for preservation of neuronal grafts.
    Type: Application
    Filed: November 5, 2001
    Publication date: September 12, 2002
    Applicant: GESTILAB INC.
    Inventors: Joanne Paquin, Mircea Alexandru Mateescu, Eric De Grandpre
  • Ceruloplasmin and an antioxidant composition comprising the same and their uses as neuroprotective agent
    Publication number: 20020094949
    Abstract: A neuroprotective composition for protecting neuronal cells against oxidative stress and methods for using and preparing the same. More particularly, the neuroprotective composition of the invention comprises a therapeutically effective amount of ceruloplasmin or a functional derivative thereof. The neuroprotective composition is characterized in that it protects neuronal cells from reactive oxygen species such as •O2− and •OH. In a preferred embodiment, the neuroprotective composition further comprises an antioxidant consisting of catalase or of an amphiphilic physiological antioxidative solution comprising a mixture of pyruvate, antioxidant, and lipid(s) such as fatty acids. The neuroprotective composition could be used for the treatment of brain trauma, brain or cerebrovascular ischemia, neurodegenerative diseases, poisoning of neuronal cells, the diminution of drugs side effects and for preservation of neuronal grafts.
    Type: Application
    Filed: November 5, 2001
    Publication date: July 18, 2002
    Applicant: GESTILAB INC.
    Inventors: Joanne Paquin, Mircea Alexandru Mateescu, Eric De Grandpre