Patents by Inventor Eric DeFrancq

Eric DeFrancq has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Coupling agents comprising a photolabile protecting group and uses thereof, such as for the functionalisation of solid supports
    Patent number: 7846875
    Abstract: The invention relates to compounds comprising a photolabile protecting group and to the use thereof as coupling agents for the functionalisation of solid supports. The invention also relates to the solid supports functionalised by said compounds and to the use of same for the immobilisation of biological molecules of interest, such as nucleic acid molecules.
    Type: Grant
    Filed: July 11, 2005
    Date of Patent: December 7, 2010
    Assignees: Commissariat A l 'Energie Atomique, Universite Joseph Fourier
    Inventors: Antoine Hoang, Françoise Vinet, Eric Defrancq, Pascal Dumy
  • PHOTOREACTIVE RU (II) COMPLEXES ANCHORED ON OLIGONUCLEOTIDES, METHOD FOR OBTAINING THEM AND USE THEREOF
    Publication number: 20100113572
    Abstract: Photoreactive Ru (II) complexes are anchored on a G-containing oligonucleotide, e.g. compound 1. The method for obtaining them and their use, includes targeting specific nucleotide sequences that become photocrosslinked to the photoreactive Ru (II) complex anchored to the G-containing oligonucleotide.
    Type: Application
    Filed: March 5, 2008
    Publication date: May 6, 2010
    Inventors: Eric Defrancq, Cécile Moucheron, Stéphane Rickling, Andrée De Mesmaeker(Kirsch)
  • Presentation of Recognition Motifs by a Multivalent Matrix Grafted Onto a Solid Support
    Publication number: 20090221449
    Abstract: The invention relates to a method for preparing a grafted homodetic cyclopeptide forming a frame defining two surfaces, one surface being known as the upper surface and the other surface being known as the lower surface, both surfaces being grafted, characterized in the a linear peptide is synthesized, said synthesis is being carried out on modified amino acids or not, some of which include orthogonal protector groups, intramolecular cyclization of the protected linear peptide thus obtained is performed, all or part of the orthogonal protector groups are substituted by a protected precursor, and at least one molecule of therapeutic interest is grafted on one and/or the other surface of the frame by means of an oxime link.
    Type: Application
    Filed: February 20, 2007
    Publication date: September 3, 2009
    Inventors: Eric Defrancq, Pascal Dumy, Olivier Renaudet, Francoise Vinet, Antoine Hoang
  • Coupling Agents Comprising A Photolabile Protecting Group And Uses Thereof, Such As For The Functionalisation Of Solid Supports
    Publication number: 20070298516
    Abstract: The invention relates to compounds comprising a photolabile protecting group and to the use thereof as coupling agents for the functionalisation of solid supports. The invention also relates to the solid supports functionalised by said compounds and to the use of same for the immobilisation of biological molecules of interest, such as nucleic acid molecules.
    Type: Application
    Filed: July 11, 2005
    Publication date: December 27, 2007
    Inventors: Antoine Hoang, Francoise Vinet, Eric Defrancq, Pascal Dumy
  • Functionalized polynucleotide compound, optionally marked and method for detecting a target nucleic acid
    Patent number: 6875858
    Abstract: The invention relates to a functionalized compound of general formula (I): in which W represents a nucleotide analog, L represents a linker arm comprising at least four atoms, R1 represents a linear or branched alkyl chain, A functionalized polynucleotide comprising at least one said compound and a labeled functionalized polynucleotide comprising at least one functionalized compound corresponding to the formula (I?). A method for detecting a target nucleic acid using a said compound is described.
    Type: Grant
    Filed: January 5, 2000
    Date of Patent: April 5, 2005
    Assignee: Bio Merieux
    Inventors: Eric DeFrancq, Ali Laayoun, Jean Lhomme, Emmanuelle Trevisiol