Patents by Inventor Eric Edward Jarvis

Eric Edward Jarvis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REGULATION OF ENDOGENOUS GENE EXPRESSION IN CELLS USING ZINC FINGER PROTEINS
    Publication number: 20170251645
    Abstract: The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Application
    Filed: April 27, 2017
    Publication date: September 7, 2017
    Inventors: George Norbert Cox, III, Casey C. Case, Stephen P. Eisenberg, Eric Edward Jarvis, Sharon Kaye Spratt
  • Regulation of endogenous gene expression in cells using zinc finger proteins
    Patent number: 9491934
    Abstract: The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Grant
    Filed: May 23, 2011
    Date of Patent: November 15, 2016
    Assignee: Sangamo BioSciences, Inc.
    Inventors: George Norbert Cox, III, Casey Christopher Case, Stephen P. Eisenberg, Eric Edward Jarvis, Sharon Kaye Spratt
  • Sub-wet bulb evaporative chiller system with multiple integrated subunits or chillers
    Patent number: 9207018
    Abstract: A cooling system integrating a plurality of evaporative chillers, which each cool water to below ambient wet bulb temperature. In an air-to-air heat exchanger of each chiller, the incoming airstream used to evaporate water from the water stream is first cooled indirectly using the cooled air that is exhausted from a saturator of an adjacent chiller or subunit. By pre-chilling the air without adding moisture, each of the chillers of the cooling system is able to achieve water temperatures below the ambient wet bulb temperature. The system integrates or “daisy chains” multiple sub-wet bulb evaporative chillers or subunits such that the cool air output from one subunit is used to pre-cool the incoming air of another neighboring unit. To this end, adjacent units have their heat exchangers fluidically connected together (e.g., air flow output from each saturator is passed as cool return air through channels of an adjacent heat exchanger).
    Type: Grant
    Filed: June 13, 2013
    Date of Patent: December 8, 2015
    Assignee: NEXAJOULE, INC.
    Inventor: Eric Edward Jarvis
  • REGULATION OF ENDOGENOUS GENE EXPRESSION IN CELLS USING ZINC FINGER PROTEINS
    Publication number: 20140325691
    Abstract: The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Application
    Filed: June 5, 2014
    Publication date: October 30, 2014
    Applicant: Sangamo BioSciences, Inc.
    Inventors: George Norbert Cox III, Casey C. Case, Stephen P. Eisenberg, Eric Edward Jarvis, Sharon Kaye Spratt
  • SUB-WET BULB EVAPORATIVE CHILLER SYSTEM WITH MULTIPLE INTEGRATED SUBUNITS OR CHILLERS
    Publication number: 20130333407
    Abstract: A cooling system integrating a plurality of evaporative chillers, which each cool water to below ambient wet bulb temperature. In an air-to-air heat exchanger of each chiller, the incoming airstream used to evaporate water from the water stream is first cooled indirectly using the cooled air that is exhausted from a saturator of an adjacent chiller or subunit. By pre-chilling the air without adding moisture, each of the chillers of the cooling system is able to achieve water temperatures below the ambient wet bulb temperature. The system integrates or “daisy chains” multiple sub-wet bulb evaporative chillers or subunits such that the cool air output from one subunit is used to pre-cool the incoming air of another neighboring unit. To this end, adjacent units have their heat exchangers fluidically connected together (e.g., air flow output from each saturator is passed as cool return air through channels of an adjacent heat exchanger).
    Type: Application
    Filed: June 13, 2013
    Publication date: December 19, 2013
    Inventor: ERIC EDWARD JARVIS
  • Regulation of endogenous gene expression in cells using zinc finger proteins
    Publication number: 20120294838
    Abstract: The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Application
    Filed: May 23, 2011
    Publication date: November 22, 2012
    Inventors: George Norbert Cox III, Casey Christopher Case, Stephen P. Eisenberg, Eric Edward Jarvis, Sharon Kaye Spratt
  • Repressing endogenous CCR5 gene expression in cells using engineered zinc finger proteins
    Patent number: 8268618
    Abstract: The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Grant
    Filed: August 16, 2006
    Date of Patent: September 18, 2012
    Assignee: Sangamo BioSciences, Inc.
    Inventors: George Norbert Cox, III, Casey Christopher Case, Stephen P. Eisenberg, Eric Edward Jarvis, Sharon Kaye Spratt
  • SUB-WET BULB EVAPORATIVE WATER CHILLER WITH GRADIENT CHILLING AND AIR-TO-AIR HEAT EXCHANGE
    Publication number: 20120204591
    Abstract: An evaporative chiller cooling water to below ambient wet bulb temperature. Sub-wet bulb chilling is achieved by pre-cooling incoming air upstream of the saturator. The incoming air is ambient air at ambient air temperature that is cooled using the coolness of the lower temperature outgoing air exiting the saturator. The pre-cooling lowers the temperature of the incoming air and lowers its wet bulb temperature below that of ambient air. The saturator water is chilled to below the ambient wet bulb temperature. The air in the saturator flows across the water as it gravity drips or flows from the top to the bottom of the saturator. The pre-cooled air flows across the saturator with the coolest air directed across the bottom of the saturator where the coldest water is flowing and with the hottest air directed across the top where the hottest water is flowing to provide gradient chilling.
    Type: Application
    Filed: April 24, 2012
    Publication date: August 16, 2012
    Inventor: Eric Edward Jarvis
  • Regulation of endogenous gene expression in cells using zinc finger proteins
    Publication number: 20110247087
    Abstract: The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Application
    Filed: May 23, 2011
    Publication date: October 6, 2011
    Inventors: George Norbert Cox, III, Casey Christopher Case, Stephen P. Eisenberg, Eric Edward Jarvis, Sharon Kaye Spratt
  • Regulation of endogenous gene expression in cells using zinc finger proteins
    Patent number: 7985887
    Abstract: The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Grant
    Filed: August 17, 2006
    Date of Patent: July 26, 2011
    Assignee: Sangamo BioSciences, Inc.
    Inventors: George Norbert Cox, III, Casey Christopher Case, Stephen P. Eisenberg, Eric Edward Jarvis, Sharon Kaye Spratt
  • Alteration of tumor growth using zinc finger proteins
    Publication number: 20100279406
    Abstract: The present invention provides methods for altering tumor growth using zinc finger proteins.
    Type: Application
    Filed: September 20, 2006
    Publication date: November 4, 2010
    Inventors: George Norbert Cox, III, Casey Christopher Case, Stephen P. Eisenberg, Eric Edward Jarvis, Sharon Kaye Spratt
  • Regulation of endogenous gene expression in cells using zinc finger proteins
    Publication number: 20100261271
    Abstract: The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Application
    Filed: September 14, 2006
    Publication date: October 14, 2010
    Inventors: George Norbert Cox, III, Casey Christopher Case, Stephen P. Eisenberg, Eric Edward Jarvis, Sharon Kaye Spratt
  • SUB-WET BULB EVAPORATIVE CHILLER WITH PRE-COOLING OF INCOMING AIR FLOW
    Publication number: 20100186438
    Abstract: An evaporative chiller cooling water to below ambient wet bulb temperature. Sub-wet bulb chilling is achieved by pre-cooling incoming air upstream of the saturator. The incoming air is ambient air at ambient air temperature that is cooled using the coolness of the lower temperature outgoing air exiting the saturator. The pre-cooling lowers the temperature of the incoming air and lowers its wet bulb temperature below that of ambient air. The saturator water is chilled to below the ambient wet bulb temperature. The air in the saturator flows across the water as it gravity drips or flows from the top to the bottom of the saturator. The pre-cooled air flows across the saturator with the coolest air directed across the bottom of the saturator where the coldest water is flowing and with the hottest air directed across the top where the hottest water is flowing to provide gradient chilling.
    Type: Application
    Filed: March 12, 2010
    Publication date: July 29, 2010
    Applicant: NEXAJOULE, INC.
    Inventor: Eric Edward Jarvis
  • Sub-wet bulb evaporative chiller with pre-cooling of incoming air flow
    Patent number: 7698906
    Abstract: An evaporative chiller cooling water to below ambient wet bulb temperature. Sub-wet bulb chilling is achieved by pre-cooling incoming air upstream of the saturator. The incoming air is ambient air at ambient air temperature that is cooled using the coolness of the lower temperature outgoing air exiting the saturator. The pre-cooling lowers the temperature of the incoming air and lowers its wet bulb temperature below that of ambient air. The saturator water is chilled to below the ambient wet bulb temperature. The air in the saturator flows across the water as it gravity drips or flows from the top to the bottom of the saturator. The pre-cooled air flows across the saturator with the coolest air directed across the bottom of the saturator where the coldest water is flowing and with the hottest air directed across the top where the hottest water is flowing to provide gradient chilling.
    Type: Grant
    Filed: December 27, 2006
    Date of Patent: April 20, 2010
    Assignee: Nexajoule, Inc.
    Inventor: Eric Edward Jarvis
  • Regulation of endogenous gene expression in cells using zinc finger proteins
    Patent number: 7163824
    Abstract: The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Grant
    Filed: August 15, 2002
    Date of Patent: January 16, 2007
    Assignee: Sangamo Biosciences, Inc.
    Inventors: George Norbert Cox, III, Casey Christopher Case, Stephen P. Eisenberg, Eric Edward Jarvis, Sharon Kaye Spratt
  • Ligand-controlled regulation of endogenous gene expression
    Patent number: 7070934
    Abstract: Disclosed herein are compositions comprising an engineered zinc finger protein and a nuclear hormone receptor transcriptional control domain, polynucleotides encoding one or more components of the compositions, methods of making the compositions and methods of using these compositions, for example to modulate gene expression and/or to generate transgenic plants or animals.
    Type: Grant
    Filed: June 5, 2003
    Date of Patent: July 4, 2006
    Assignee: Sangamo Biosciences, Inc.
    Inventors: George Norbert Cox, III, Casey Christopher Case, Stephen P. Eisenberg, Eric Edward Jarvis, Sharon Kaye Spratt
  • Regulation of endogenous gene expression in cells using zinc finger proteins
    Patent number: 6979539
    Abstract: The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Grant
    Filed: July 2, 2001
    Date of Patent: December 27, 2005
    Assignee: Sangamo BioSciences, Inc.
    Inventors: George Norbert Cox, III, Casey Christopher Case, Stephen P. Eisenberg, Eric Edward Jarvis, Sharon Kaye Spratt
  • Regulation of endogenous gene expression in cells using zinc finger proteins
    Patent number: 6824978
    Abstract: The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Grant
    Filed: November 3, 2000
    Date of Patent: November 30, 2004
    Assignee: Sangamo Biosciences, Inc.
    Inventors: George Norbert Cox, III, Casey Christopher Case, Stephen P. Eisenberg, Eric Edward Jarvis, Sharon Kaye Spratt
  • Regulation of endogenous gene expression in cells using zinc finger proteins
    Publication number: 20030087817
    Abstract: The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Application
    Filed: July 2, 2001
    Publication date: May 8, 2003
    Applicant: Sangamo BioSciences, Inc.
    Inventors: George Norbert Cox, Casey Christopher Case, Stephen P. Eisenberg, Eric Edward Jarvis, Sharon Kaye Spratt
  • Regulation of endogenous gene expression in cells using zinc finger proteins
    Patent number: 6534261
    Abstract: The present invention provides methods for modulating expression of endogenous cellular genes using recombinant zinc finger proteins.
    Type: Grant
    Filed: January 12, 1999
    Date of Patent: March 18, 2003
    Assignee: Sangamo BioSciences, Inc.
    Inventors: George Norbert Cox, III, Casey Christopher Case, Stephen P. Eisenberg, Eric Edward Jarvis, Sharon Kaye Spratt