Patents by Inventor Eric Edwards
Eric Edwards has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250259701Abstract: Disclosed herein are systems, devices, and methods for identifying recombinant variants (such as gene conversion variants) of genes such as RHD gene and RHCE gene, the copy numbers of recombinant variants, and gene variant status (for example, heterozygous or homozygous). In some embodiments, the disclosed systems, devices, and methods include steps of receiving sequence reads which align to a RHD gene or a RHCE gene, estimating a combined copy number of a RHD gene and a RHCE gene, estimating copy numbers of a RHD-specific base and a RHCE-specific base at each of a plurality of pre-determined differentiating sites of the RHD gene and the RHCE gene, and calculating a probability of a RHCE*CE-D(2)-CE gene conversion in the nucleic acid sample.Type: ApplicationFiled: June 5, 2023Publication date: August 14, 2025Inventors: Vitor Ferreira Onuchic, Christine Amalachukwu Anyansi, Massimiliano Rossi, Xiao Chen, Michael Eberle, Eric Edward Roller
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Publication number: 20250253017Abstract: A method for determining trial designs that includes obtaining simulation data for a set of trial designs that includes combinations of design options for a set of criteria. The simulation data includes performance parameters and performance parameter values associated with each design in the set of trial designs for the set of criteria. The method further includes determining an optimality criteria for evaluating the trial designs. The optimality criteria includes at least one of Pareto optimality or convex hull optimality for clinical trial design performance values. The method further includes: determining at least one of a cooling cycle, a parameter change, or a direction; and searching, within the set of trial designs, for a set of globally optimum designs based on the optimality criteria using simulated annealing. The simulated annealing is based at least in part on at least one of the cooling cycle, the parameter change, or the direction.Type: ApplicationFiled: March 18, 2025Publication date: August 7, 2025Inventors: Jaydeep Bhattacharyya, James Bolognese, Alexandre Buer, Eric Edwards, Stanley Y. Huang, Yannis Jemiai, Cyrus Mehta, Nitin Patel, Anne Pelz, Ajay Prabhakar Sathe, Joshua A. Schultz, Pralay Senchaudhuri
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Patent number: 12357746Abstract: Embodiments of negative pressure wound therapy systems and methods for operating the systems are disclosed. In some embodiments, a system includes a negative pressure source, a wound dressing configured to be positioned over a wound, and optionally a canister configured to store fluid aspirated from the wound. The negative pressure source, wound dressing, and canister (when present) can be fluidically connected to facilitate delivery of negative pressure to the wound. The system can be configured to automatically detect whether the canister is positioned in the fluid flow path between the negative pressure source and the dressing while negative pressure source provides negative pressure to the wound dressing. Operation of the system can be adjusted based on whether presence of the canister has been detected. For example, a value of an operational parameter can be set to indicate that the canister is present.Type: GrantFiled: June 29, 2022Date of Patent: July 15, 2025Assignee: Smith & Nephew, Inc.Inventors: Eric Edward Adams, Kevin Bendele, Aaron Michael Husz, David Edward Lee, Felix Clarence Quintanar, Lee Michael Rush, David Ronald Upton, William Jacob Ward
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Publication number: 20250217513Abstract: Protecting sensitive data from unauthorized disclosure is provided. For example, systems, methods, and computer readable storage devices are described that may be operable or configured to tokenize sensitive data attributes that may be included in a data file received from a client. Tokens that are anonymized but representative of the attributes may be generated and mapped to the sensitive data attributes. A tokenized data file may be de-tokenized and re-tokenized to perform processes that require the sensitive data attributes. A document may be transformed to protect the sensitive data attributes while reducing risk of disclosure of the sensitive data.Type: ApplicationFiled: October 15, 2024Publication date: July 3, 2025Applicant: RevSpring, Inc.Inventors: Lino Etollo Carnesecca, Shawn Michael Mox, Scott Andrew Astheimer, Eric Edward Martin, Cliff Lee Curtis, Jesse Alan Yeager, Miguel Dawson
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Patent number: 12322479Abstract: A method for determining trial designs is provided. The method includes obtaining simulation data for a set of trial designs. The simulation data includes performance parameters and performance parameter values associated with each design in the set of designs for a set of criteria; determining an optimality criteria for evaluating the trial designs; searching, within the set of trial designs, for globally optimum designs based on the optimality criteria; and recommending globally optimum designs.Type: GrantFiled: January 30, 2021Date of Patent: June 3, 2025Assignee: Cytel Inc.Inventors: Jaydeep Bhattacharyya, James Bolognese, Alexandre Buer, Eric Edwards, Stanley Y. Huang, Yannis Jemiai, Cyrus Mehta, Nitin Patel, Anne Pelz, Ajay Prabhakar Sathe, Joshua A. Schultz, Pralay Senchaudhuri
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Patent number: 12211593Abstract: A method, according to some implementations, includes obtaining trial design simulation results for a set of trial designs and determining a set of Pareto designs in the set of trial designs based at least in part on the trial design simulation results and one or more performance parameters. The method further includes determining a set of convex hull designs in the set of trial designs, determining a set of recommended designs based at least in part on the set of Pareto designs and the set of convex hull designs, and transmitting the set of recommended designs.Type: GrantFiled: January 30, 2021Date of Patent: January 28, 2025Assignee: Cytel Inc.Inventors: Jaydeep Bhattacharyya, James Bolognese, Alexandre Buer, Eric Edwards, Stanley Y. Huang, Yannis Jemiai, Cyrus Mehta, Nitin Patel, Anne Pelz, Ajay Prabhakar Sathe, Joshua A. Schultz, Pralay Senchaudhuri
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Publication number: 20250024523Abstract: The disclosure describes techniques for configuring wireless routers of a wireless mesh network with one or more secondary wireless access points (WAPs) such that client devices connected to the mesh network may remain online in the event that a primary WAP goes offline or otherwise becomes unavailable. For instance, a user of the wireless mesh network may specify a device, such as a mobile electronic device connected to a cellular network, to operate as a secondary WAP in the event that a primary WAP becomes unavailable. Thereafter, upon a wireless router of the mesh network detecting that the primary WAP is unavailable, the wireless router may perform a network scan to identify SSID(s) that are available within the environment. The wireless router may also instruct the other routers of the mesh network to perform a network scan.Type: ApplicationFiled: September 26, 2023Publication date: January 16, 2025Inventors: Denny Drivas Delp, Casey Eric Edwards, Hsuan-Man Hung, Wei-Chun Wang, Matthew James Richards, Benjamin Jeffrey Lowe
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Publication number: 20250022551Abstract: A method for searching clinical trial designs that includes: determining a first convex hull set from a first set of clinical trial designs for a first scenario; simulating the first convex hull set for a second scenario to determine first simulation results; removing the first convex hull set from the first set of clinical trial designs to generate a second set of clinical trial designs; determining a second convex hull set from the second set of clinical trial designs for the first scenario; simulating the second convex hull set for the second scenario to determine second simulation results; determining, based at least in part on the first simulation results and the second simulation results, a refined scenario convex hull set of clinical trial designs for the second scenario from the first convex hull set and the second convex hull set; and transmitting the refined scenario convex hull set.Type: ApplicationFiled: September 27, 2024Publication date: January 16, 2025Inventors: Jaydeep Bhattacharyya, James Bolognese, Alexandre Buer, Eric Edwards, Stanley Y. Huang, Yannis Jemiai, Cyrus Mehta, Nitin Patel, Anne Pelz, Ajay Prabhakar Sathe, Joshua A. Schultz, Pralay Senchaudhuri
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Publication number: 20250000883Abstract: This invention relates to, among other items, treating Alzheimer's disease by administering epetraborole, or a salt, hydrate or solvate thereof, to a patient in need of treatment thereof.Type: ApplicationFiled: October 27, 2022Publication date: January 2, 2025Applicant: AN2 Therapeutics, Inc.Inventors: Eric Edward EASOM, Vincent S. HERNANDEZ, Michael Richard Kevin ALLEY
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Patent number: 12162221Abstract: A build unit for additively manufacturing three-dimensional objects may include an energy beam system having one or more irradiation devices respectively configured to direct one or more energy beams onto a region of a powder bed, and an inertization system including an irradiation chamber defining an irradiation plenum, one or more supply manifolds, and a return manifold. The one or more supply manifolds may include a downflow manifold configured to provide a downward flow of a process gas through at least a portion of the irradiation plenum, and/or a crossflow manifold configured to provide a lateral flow of the process gas through at least a portion of the irradiation plenum. The return manifold may evacuate process gas from the irradiation plenum. While irradiating the region of the powder bed, the process gas may flow through the one or more supply manifolds, into the irradiation plenum, and into the return manifold.Type: GrantFiled: April 16, 2021Date of Patent: December 10, 2024Assignees: General Electric Company, Concept Laser GmbHInventors: Eric Edward Halla, Ramakrishna Venkata Mallina, Kishore Ramakrishnan, Shashwat Swami Jaiswal, Mohammed Mounir Shalaby, Peter Pontiller-Schymura
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Publication number: 20240404657Abstract: A method for determining trial designs is provided. The method includes receiving, via at least one processor, one or more trial design criteria and one or more scenarios corresponding to a set of trial designs, and generating, via the at least one processor, simulation data based at least in part on replicating each of the set of trial designs with the one or more trial design criteria and the one or more scenarios. The simulation data includes performance parameters and performance parameter values associated with each design in the set of designs for a set of criteria. The method further includes determining, via the at least one processor, an optimality criteria for evaluating the trial designs, searching, within the set of trial designs, via the at least one processor, for globally optimum designs based on the optimality criteria, and transmitting, via the at least one processor, globally optimum designs.Type: ApplicationFiled: June 6, 2024Publication date: December 5, 2024Inventors: Jaydeep Bhattacharyya, James Bolognese, Alexandre Buer, Eric Edwards, Stanley Y. Huang, Yannis Jemiai, Cyrus Mehta, Nitin Patel, Anne Pelz, Ajay Prabhakar Sathe, Joshua A. Schultz, Pralay Senchaudhuri
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Patent number: 12147573Abstract: Protecting sensitive data from unauthorized disclosure is provided. For example, systems, methods, and computer readable storage devices are described that may be operable or configured to tokenize sensitive data attributes that may be included in a data file received from a client. Tokens that are anonymized but representative of the attributes may be generated and mapped to the sensitive data attributes. A tokenized data file may be de-tokenized and re-tokenized to perform processes that require the sensitive data attributes. A document may be transformed to protect the sensitive data attributes while reducing risk of disclosure of the sensitive data.Type: GrantFiled: December 16, 2021Date of Patent: November 19, 2024Assignee: REVSPRING, INC.Inventors: Lino Etollo Carnesecca, Shawn Michael Mox, Scott Andrew Astheimer, Eric Edward Martin, Cliff Lee Curtis, Jesse Alan Yeager, Miguel Dawson
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Patent number: 12118672Abstract: A three dimensional representation of sports data from multiple sources, which has A) a computer program stored on a non-transitory computer readable medium, B) a server operatively associated with the non-transitory computer readable medium, C) a computer vision model using feature detection algorithms, D) a database associated to the computer vision model, E) data to upload to the database, F) a graphical user interface to show data, and G) a computer device, whereby users access to the graphical user interface to upload and visualize the data. The data is visually shown through two-dimension and three-dimension images, text, numbers, animations, and custom visuals to allow the users to analyze the data.Type: GrantFiled: September 7, 2022Date of Patent: October 15, 2024Assignee: DATRAKS, LLCInventors: Ryan James Reinsel, Matthew Kenneth Schafer, Eric Edward Albers, Joseph Eli Sleiman, Kevin Davidson
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Patent number: 12103107Abstract: A method of aligning at least one laser beam of an additive manufacturing arrangement. The method includes measuring a surface of the calibration plate at a plurality of measurement points using the coordinate measuring machine. The method further includes generating a correction field based on the plurality of measurement points using the coordinate measuring machine. The method further includes writing at least one fiducial mark on the surface of the calibration plate using the at least one laser beam. The method further includes generating calibration data for the surface of the calibration plate using the calibration system. The method also includes aligning the laser beam within the additive manufacturing system based on the calibration data and the correction field using the computing device by comparing a position of the fiducial mark from the calibration data with the correction field to determine a corrected position of the laser beam.Type: GrantFiled: July 18, 2019Date of Patent: October 1, 2024Assignee: General Electric CompanyInventors: Brian Scott McCarthy, Eric Edward Halla, Thomas Charles Adcock, Michael Evans Graham, Andrea Marie Schmitz, Mark Samuel Bailey
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Publication number: 20240252896Abstract: A command measurement system employs a ball flight tracking system that measures the location of a ball as it breaks the plane of the strike zone. The command measurement system also employs an intended pitch location system that provides the pitcher with a wireless signal to inform the pitcher of the intended pitch location. This intended pitch location target forms the pitcher's intent of where he or she is trying to pitch the ball. The measured pitch location is compared to the intended pitch location and a measure of command is determined by the amount of deviation of the measured location from the intended pitch location.Type: ApplicationFiled: March 15, 2024Publication date: August 1, 2024Inventors: Eric Edward ALBERS, Matthew SCHAFER, Jonathan Johnson GOMES, Craig Anthony FILICETTI, John Andrew HANKINS
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Patent number: 12051488Abstract: A method for trial design includes presenting on a graphical interface, a set of cards, wherein each card in the set is representative of a different trial design from a set of trial designs. The method further includes: monitoring a first set of user interactions with the set of cards; determining a user preference for one or more values of one or more parameters of the set of trial designs from the first set of user interactions; and presenting on the graphical interface a new card that is representative of a trial design consistent with the determined user preference. The method may also include monitoring a second set of user interactions with the new card and refining the determined user preference based at least in part on the second set of user interactions with the new card.Type: GrantFiled: January 30, 2021Date of Patent: July 30, 2024Assignee: Cytel Inc.Inventors: Jaydeep Bhattacharyya, James Bolognese, Alexandre Buer, Eric Edwards, Stanley Y. Huang, Yannis Jemiai, Cyrus Mehta, Nitin Patel, Anne Pelz, Ajay Prabhakar Sathe, Joshua A. Schultz, Pralay Senchaudhuri
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Publication number: 20240250815Abstract: Systems and methods are provided for implementing encryption of data-in-motion and/or otherwise stored data using a key server and a secure enclave of a Network Interface Card (NIC). The NIC acts as a passthrough between the client device and the shared infrastructure of the supercomputer system to help ensure data security in a massively scaled and distributed system. For example, in response to an enrollment process that stores a decrypted key in the secure enclave of a NIC, the NIC can receive a data packet from a client device. The NIC can transmit a key request to a key server that includes an encrypted key corresponding to the decrypted key. The key server can look up the previously stored private/public key pair to authenticate the NIC. The key server can provide private/public key pair to the NIC to allow the NIC to later encrypt data-in-motion.Type: ApplicationFiled: November 21, 2023Publication date: July 25, 2024Inventors: KEITH D. UNDERWOOD, Duncan Roweth, Michael R. Strom, Eric Edward Eilertson
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Patent number: 12040059Abstract: A method for determining trial designs is provided. The method includes receiving, via at least one processor, one or more trial design criteria and one or more scenarios corresponding to a set of trial designs, and generating, via the at least one processor, simulation data based at least in part on replicating each of the set of trial designs with the one or more trial design criteria and the one or more scenarios. The simulation data includes performance parameters and performance parameter values associated with each design in the set of designs for a set of criteria. The method further includes determining, via the at least one processor, an optimality criteria for evaluating the trial designs, searching, within the set of trial designs, via the at least one processor, for globally optimum designs based on the optimality criteria, and transmitting, via the at least one processor, globally optimum designs.Type: GrantFiled: January 30, 2021Date of Patent: July 16, 2024Assignee: Cytel Inc.Inventors: Jaydeep Bhattacharyya, James Bolognese, Alexandre Buer, Eric Edwards, Stanley Y. Huang, Yannis Jemiai, Cyrus Mehta, Nitin Patel, Anne Pelz, Ajay Prabhakar Sathe, Joshua A. Schultz, Pralay Senchaudhuri
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Publication number: 20240198425Abstract: A build unit for additively manufacturing three-dimensional objects may include an energy beam system, an irradiation chamber, an inertization system having a return manifold configured to evacuate a process gas from the irradiation chamber. The return manifold includes a plurality of return manifold bodies and return manifold inlet disposed at a bottom of the irradiation chamber. The plurality of return manifold bodies includes one or more return manifold pathways downstream of the return manifold inlet. The plurality of return manifold bodies also includes one or more recapture pathways positioned to receive the process gas into the one or more return manifold pathways that flows past the return manifold inlet.Type: ApplicationFiled: February 28, 2024Publication date: June 20, 2024Inventors: Eric Edward Halla, Ramakrishna Venkata Mallina, Kishore Ramakrishnan, Shashwat Swami Jaiswal, Mohammed Mounir Shalaby, Peter Pontiller-Schymura
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Patent number: D1041428Type: GrantFiled: February 23, 2022Date of Patent: September 10, 2024Assignee: Venture Offroad Engineering LLCInventors: Brandon Wilson, Marcus Dethloff, Eric Edwards