Patents by Inventor Eric Ferrari

Eric Ferrari has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • HCV replicase complexes
    Patent number: 6967075
    Abstract: This invention provides efficient HCV replicase complexes comprising novel RNA template and primer pair. Assay systems are also provided, which use such complexes, for detecting replicase activity, quantitatively studying the kinetics and mechanism of HCV NS5B-catalyzed nucleotide incorporation, and identifying inhibitors of HCV replicase. The assay systems use small and well-defined synthetic RNAs which allow efficient assembly of all catalytic components in the quaternary complex for HCV NS5B-directed RNA replication. Specific template-primer requirements for efficient RNA synthesis by HCV NS5B replicase are provided for use in assay systems.
    Type: Grant
    Filed: April 6, 2001
    Date of Patent: November 22, 2005
    Assignee: Schering Corporation
    Inventors: Weidong Zhong, Zhi Hong, Eric Ferrari
  • HCV replicase complexes
    Publication number: 20020064771
    Abstract: This invention provides efficient HCV replicase complexes comprising novel RNA template and primer pair. Assay systems are also provided, which use such complexes, for detecting replicase activity, quantitatively studying the kinetics and mechanism of HCV NS5B-catalyzed nucleotide incorporation, and identifying inhibitors of HCV replicase. The assay systems use small and well-defined synthetic RNAs which allow efficient assembly of all catalytic components in the quaternary complex for HCV NS5B-directed RNA replication. Specific template-primer requirements for efficient RNA synthesis by HCV NS5B replicase are provided for use in assay systems.
    Type: Application
    Filed: April 6, 2001
    Publication date: May 30, 2002
    Inventors: Weidong Zhong, Zhi Hong, Eric Ferrari