Abstract: The invention relates to compounds of formula (I) as follows: (I) wherein X1 and X2, identical or different, are NR5 or a sulfur atom, Y is a group (C1-C10)alkanediyl, Ar1 and Ar2, identical or different, are an aryl group optionally substituted by one or several groups selected from a halogen atom, a (C1-C6) alkyl, —OR1, —NR1R2 and —COOR3? with R1 and R2, independently of each other, are a hydrogen atom, a (C-1-C6) alkyl group or a —COR3 group, R3 and R4? independently of each other, are a hydrogen atom or a (C1-C6) alkyl group, and R5 is a hydrogen atom or a (C1-C6)alkyl group, or a pharmaceutically acceptable salt and/or solvate thereof, in particular for use in cancer treatment.

Abstract: A locking chair adjustment mechanism for adjusting a position of a chair component. The mechanism comprises a central shaft, a spiral jaw clutch comprising two interconnecting spiral jaw interfaces and a slotted element wherein the slot is sized to slideably receive the central shaft for displacement of the slotted element when the mechanism is in an unlocked position. A locking pad locks the mechanism against the slotted element. A rotatable adjustment handle allows the mechanism to toggle from a locked position, to an unlocked position, by displacement of the spring mechanism caused by the rotation of the spiral jaw interface fixedly mounted on the adjustment handle, therefore releasing pressure on the locking pad. A spring mechanism is activated when the claimed mechanism goes from a locked position to an unlocked position, pulling the claimed mechanism back to a locked position. The claimed mechanism provides a low cost solution offering better locking capabilities than traditional braking mechanisms.

Abstract: A locking mechanism for chairs such as gliding and rocking chairs comprises a toothed rack for connection to the chair seat with the rack oriented generally in the direction of movement of the chair seat relative to the base and the teeth extending along the rack and facing towards a pin that is carried in the base. The rear end of the rack is pivoted to the chair seat and the front end of the rack is connected to a pivoting linkage arrangement operated by a lever at the side of the chair seat. Operation of the lever is effective to swing the toothed rack from a retracted position to a lowered position wherein the locking pin is engaged by a registering tooth in the rack. The attitude of the chair in the locked position will depend upon the position of the locking interengagement between the pin and the toothed rack.