Patents by Inventor Eric Francotte

Eric Francotte has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20140114058
    Abstract: The invention relates to substantially photochemically or thermally cross-linked polysaccharide derivatives in which the OH groups as OR groups have been esterified or converted into carbamate (urethane) or mixtures thereof and that do not contain photopolymerisable functional groups prior to the cross-linking. They can be used as carrier materials for the chromatographic separation of enantiomers.
    Type: Application
    Filed: December 20, 2013
    Publication date: April 24, 2014
    Applicant: NOVARTIS AG
    Inventors: Eric FRANCOTTE, Tong ZHANG
  • Publication number: 20120277194
    Abstract: Compounds of formula I: wherein R1, R2, n and m are as defined in the specification, processes for their production, their uses and pharmaceutical compositions containing them.
    Type: Application
    Filed: July 11, 2012
    Publication date: November 1, 2012
    Inventors: Rainer ALBERT, Eric FRANCOTTE, Frédéric ZECRI, Markus ZOLLINGER
  • Publication number: 20110118210
    Abstract: Compounds of formula I: wherein R1, R2, n and m are as defined in the specification, processes for their production, their uses and pharmaceutical compositions containing them.
    Type: Application
    Filed: January 28, 2011
    Publication date: May 19, 2011
    Inventors: Rainer ALBERT, Eric Francotte, Frédéric Zecri, Markus Zollinger
  • Patent number: 7902175
    Abstract: Compounds of formula I: wherein R1, R2, n and m are as defined in the specification, processes for their production, their uses and pharmaceutical compositions containing them.
    Type: Grant
    Filed: February 24, 2009
    Date of Patent: March 8, 2011
    Assignee: Novartis AG
    Inventors: Rainer Albert, Eric Francotte, Frederic Zecri, Markus Zollinger
  • Publication number: 20090156556
    Abstract: Compounds of formula I: wherein R1, R2, n and m are as defined in the specification, processes for their production, their uses and pharmaceutical compositions containing them.
    Type: Application
    Filed: February 24, 2009
    Publication date: June 18, 2009
    Inventors: Rainer Albert, Eric Francotte, Frederic Zecri, Markus Zollinger
  • Patent number: 7528120
    Abstract: Compounds of formula I: wherein R1, R2, n and m are as defined in the specification, processes for their production, their uses and pharmaceutical compositions containing them.
    Type: Grant
    Filed: August 27, 2004
    Date of Patent: May 5, 2009
    Assignee: Novartis AG
    Inventors: Rainer Albert, Eric Francotte, Frédéric Zecri, Markus Zollinger
  • Publication number: 20080132695
    Abstract: The invention relates to substantially photochemically or thermally cross-linked polysaccharide derivatives in which the OH groups as OR groups have been esterified or converted into carbamate (urethane) or mixtures thereof and that do not contain photopolymerisable functional groups prior to the cross-linking. They can be used as carrier materials for the chromatographic separation of enantiomers.
    Type: Application
    Filed: February 14, 2008
    Publication date: June 5, 2008
    Inventors: Eric Francotte, Tong Zhang
  • Patent number: 6011149
    Abstract: The present invention relates to photochemically cross-linked derivatives of general formulae (IA) and (IB), wherein R is a polysaccharide radical in which the OH groups have been esterified as OR' groups or converted into a carbamate (urethane), R.sub.1, and R.sub.2 are each independently lower alkyl or unsubstituted or substituted aryl, X is a direct bond or phenylene, m is 0 or 1, and n is 0 or an integer from 1 to 20, to processes from the preparation thereof and to the use thereof. The compounds of general formula (IA) and (IB) can be used as supports in the chromatographic separation of enantiomers.
    Type: Grant
    Filed: September 2, 1997
    Date of Patent: January 4, 2000
    Assignee: Novartis AG
    Inventor: Eric Francotte
  • Patent number: 5948904
    Abstract: The invention relates to a process for the preparation of polysaccharide-N-arylcarbamates in suitable form as supports for chromatography, which process comprises adding to polysaccharide carbamates, which may be substituted in the aryl moiety, an N-aryl-1-lower-alkylcarbamate-containing solution of an organic solvent, with vigorous stirring, until the polysaccharide derivative is completely dissolved and then adding thereto an aqueous solution containing a high molecular weight surfactant and, with continued stirring, removing the organic solvent from the emulsion so obtained and isolating the solid particles and washing and drying them. The polysaccharide derivatives so obtained can be used as support materials for the chromatographic separation of enantiomers.
    Type: Grant
    Filed: September 2, 1997
    Date of Patent: September 7, 1999
    Assignee: Novartis AG
    Inventor: Eric Francotte
  • Patent number: 5684199
    Abstract: The present invention is directed to a process for preparing formoterol and related compounds and derivatives thereof and their pharmacologically and pharmaceutically acceptable fumarate salts and/or solvates. The present invention is also directed to certain formoterol related compounds per se.
    Type: Grant
    Filed: June 13, 1996
    Date of Patent: November 4, 1997
    Assignee: Novartis Corporation
    Inventor: Eric Francotte
  • Patent number: 5635524
    Abstract: The invention relates to novel substituted oxazolidines of formula (I) wherein R.sub.1 and R.sub.2 are simultaneously hydrogen or both together are the identical lower alkyl radical, and to the salts thereof in racemic and chiral form, to a process for the preparation of said compounds, to pharmaceutical compositions containing them, and to the use thereof as medicaments. The compounds have a stimulating effect on beta-adrenergic receptors and can be used, inter alia, for the treatment of diseases associated with reversible obstruction of the respiratory tract, typically asthma and chronic bronchitis, and also for inflammation of different origin.
    Type: Grant
    Filed: June 10, 1996
    Date of Patent: June 3, 1997
    Assignee: Ciba-Geigy Corporation
    Inventors: Alfred Sallmann, Hans-Peter Gschwind, Eric Francotte
  • Patent number: 5369117
    Abstract: The present invention relates to novel oxazolidines of formula (1) ##STR1## wherein R.sub.1 and R.sub.2 are simultaneously hydrogen or both are the same lower alkyl radical or together are 4- to 7-membered lower alkylene, and to the salts thereof in racemic and chiral form, to the preparation of these novel compounds, to pharmaceutical compositions containing them and to the use thereof as medicaments. The compounds have a stimulating effect on beta-adrenergic receptors and can be used, inter alia, for the treatment of diseases associated with reversible obstruction of the respiratory tract, typically asthma and chronic bronchitis, and also for inflammations of different origin.
    Type: Grant
    Filed: August 17, 1993
    Date of Patent: November 29, 1994
    Assignee: Ciba-Geigy Corporation
    Inventors: Alfred Sallmann, Hans-Peter Gschwind, Eric Francotte
  • Patent number: 5091520
    Abstract: Finely particulate cellulose esters of aromatic or aromatic-aliphatic carboxylic acids in the form of substantially spherical, partially crystalline particles having an average diameter of 1 to 200 .mu.m and a specific surface area of 10 to 300 m.sup.2 /g, are suitable for use as stationary phase in methods of chromatographic separation, especially for the resolution of racemates.
    Type: Grant
    Filed: September 5, 1990
    Date of Patent: February 25, 1992
    Assignee: Ciba-Geigy Corporation
    Inventors: Eric Francotte, Gabriele Baisch
  • Patent number: 5066793
    Abstract: Finely particulate cellulose esters of aromatic or aromatic-aliphatic carboxylic acids in the form of substantially spherical, partially crystalline particles having an average diameter of 1 to 200 .mu.m and a specific surface area of 10 to 300 m.sup.2 /g, are suitable for use as stationary phase in methods of chromatographic separation, especially for the resolution of racemates.
    Type: Grant
    Filed: October 13, 1988
    Date of Patent: November 19, 1991
    Assignee: Ciba-Geigy Corporation
    Inventors: Eric Francotte, Gabriele Baisch
  • Patent number: 5026841
    Abstract: Process for the preparation of finely divided porous cellulose in the form of essentially spherical particles by formation of a suspension, in which an organic solution of a cellulose ester of aromatic or aromatic-aliphatic carboxylic acids containing a C.sub.5 -C.sub.12 alkanol is stirred into an aqueous solution of an anionic surfactant, the solvent is removed and the particles are isolated and hydrolyzed under heterogeneous conditions. They are suitable as adsorbents in e.g. chromatographic processes.
    Type: Grant
    Filed: June 16, 1989
    Date of Patent: June 25, 1991
    Assignee: Ciba-Geigy Corporation
    Inventors: Eric Francotte, Gabriele Baisch
  • Patent number: 4778895
    Abstract: The invention relates to enantiomers of 1-(6-phenoxy-2-pyridyl)ethanols of the formula ##STR1## wherein * is (+) or (-) and X and Y are each independently of the other hydrogen, halogen, nitro, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.2 -C.sub.5 alkenyl or C.sub.2 -C.sub.5 alkynyl.The invention also relates to the preparation of these enantiomers and to their use for the preparation of biocidal compounds.
    Type: Grant
    Filed: April 6, 1987
    Date of Patent: October 18, 1988
    Assignee: Ciba-Geigy Corporation
    Inventors: Eric Francotte, Peter Ackermann