Patents by Inventor Eric Gould Gundersen

Eric Gould Gundersen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1)
    Patent number: 7629377
    Abstract: This invention provides PAI-1 inhibiting compounds of Formula I: wherein: R1, R2, R3, and R4 are each H, alkyl, alkanoyl, halo, OH, aryl optionally substituted with R8, perfluoroalkyl, alkoxy, amino, alkylamino, dialkylamino, perfluoroalkoxy; R5 is H, alkyl, perfluoroalkyl, aryl optionally substituted with R5, alkanoyl, aroyl optionally substituted with R8; R6 is H, alkyl, alkylaryl, benzyl optionally substituted with R8, alkanoyl, aroyl optionally substituted with R8; R7 is H, alkyl, alkylaryl, aryl optionally substituted with R8; n is 0-6; A is COOH, or an acid mimic such as tetraazole, SO3H, PO3H2, tetronic acid, etc.; R8 is H, alkyl, cycloalkyl, alkanoyl, halo, OH, perfluoroalkyl, alkoxy, amino, alkylamino, dialkylamino, perfluoroalkoxy; or a pharmaceutically acceptable salt thereof; as well as pharmaceutical compositions and methods of treatment using these compounds.
    Type: Grant
    Filed: February 5, 2008
    Date of Patent: December 8, 2009
    Assignee: Wyeth
    Inventors: David LeRoy Crandall, Scott Christian Mayer, Eric Gould Gundersen, Hassan Mahmoud Elokdah
  • Substituted phenyl indoles
    Patent number: 7582773
    Abstract: The present invention relates generally to substituted phenyl indoles and methods of using them, for example as PAI-1 inhibitors.
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: September 1, 2009
    Assignee: Wyeth
    Inventor: Eric Gould Gundersen
  • SUBSTITUTED ARYL OXIMES
    Publication number: 20080293790
    Abstract: The present invention relates to substituted aryl oximes and methods of using them.
    Type: Application
    Filed: July 28, 2008
    Publication date: November 27, 2008
    Applicant: Wyeth
    Inventors: Lisa Marie Havran, John Anthony Butera, Hassan Mahmoud Elokdah, Douglas John Jenkins, Eric Gould Gundersen
  • Substituted aryloximes
    Patent number: 7420083
    Abstract: The present invention relates to substituted aryl oximes and methods of using them.
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: September 2, 2008
    Assignee: Wyeth
    Inventors: Lisa Marie Havran, John Anthony Butera, Hassan Mahmoud Elokdah, Douglas John Jenkins, Eric Gould Gundersen
  • SUBSTITUTED NAPHTHYL INDOLE DERIVATIVES AS INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR TYPE-1 (PAI-1)
    Publication number: 20080182883
    Abstract: This invention provides PAI-1 inhibiting compounds of Formula I: wherein: R1, R2, R3, and R4 are each H, alkyl, , alkanoyl, halo, OH, aryl optionally substituted with R8, perfluoroalkyl, alkoxy, amino, alkylamino, dialkylamino, pertluoroalkoxy; R5 is H, alkyl, perfluoroalkyl, aryl optionally substituted with R5, alkanoyl, aroyl optionally substituted with R8; R6 is H, alkyl, alkylaryl, benzyl optionally substituted with R8, alkanoyl, aroyl optionally substituted with R8; R7 is H, alkyl, alkylaryl, aryl optionally substituted with R8; n is 0-6; A is COOH, or an acid mimic such as tetraazole, SO3H, PO3H2, tetronic acid, etc.; R8 is H, alkyl, cycloalkyl, alkanoyl, halo, OH, perfluoroalkyl, alkoxy, amino, alkylamino, dialkylamino, perfluoroalkoxy; or a pharmaceutically acceptable salt thereof; as well as pharmaceutical compositions and methods of treatment using these compounds.
    Type: Application
    Filed: February 5, 2008
    Publication date: July 31, 2008
    Applicant: Wyeth
    Inventors: David LeRoy Crandall, Scott Christian Mayer, Eric Gould Gundersen, Hassan Mahmoud Elokdah
  • Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1)
    Patent number: 7351730
    Abstract: This invention provides PAI-1 inhibiting compounds of Formula I: wherein: R1, R2, R3, and R4 are each H, alkyl, alkanoyl, halo, OH, aryl optionally substituted with R8, perfluoroalkyl, alkoxy, amino, alkylamino, dialkylamino, perfluoroalkoxy; R5 is H, alkyl, perfluoroalkyl, aryl optionally substituted with R8, alkanoyl, aroyl optionally substituted with R8; R6 is H, alkyl, alkylaryl, benzyl optionally substituted with R8, alkanoyl, aroyl optionally substituted with R8; R7 is H, alkyl, alkylaryl, aryl optionally substituted with R8; n is 0-6; A is COOH, or an acid mimic such as tetraazole, SO3H, PO3H2, tetronic acid, etc.; R8 is H, alkyl, cycloalkyl, alkanoyl, halo, OH, perfluoroalkyl, alkoxy, amino, alkylamino, dialkylamino, perfluoroalkoxy; or a pharmaceutically acceptable salt thereof; as well as pharmaceutical compositions and methods of treatment using these compounds.
    Type: Grant
    Filed: June 22, 2005
    Date of Patent: April 1, 2008
    Assignee: Wyeth
    Inventors: Scott Christian Mayer, Eric Gould Gundersen, Hassan Mahmoud Elokdah, David LeRoy Crandall
  • Substituted indole oximes
    Patent number: 7342039
    Abstract: The present invention relates to substituted indole oximes and methods of using them.
    Type: Grant
    Filed: September 23, 2004
    Date of Patent: March 11, 2008
    Assignee: Wyeth
    Inventors: Lisa Marie Havran, John Anthony Butera, Hassan Mahmoud Elokdah, Douglas John Jenkins, Eric Gould Gundersen
  • Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor Type-1 (PAI-1)
    Patent number: 6939886
    Abstract: This invention provides PAI-1 inhibiting compounds of Formula I: wherein: R1, R2, R3, and R4 are each H, alkyl, alkanoyl, halo, OH, aryl optionally substituted with R8, perfluoroalkyl, alkoxy, amino, alkylamino, dialkylamino, perfluoroalkoxy; R5 is H, alkyl, perfluoroalkyl, aryl optionally substituted with R8, alkanoyl, aroyl optionally substituted with R8; R6 is H, alkyl, alkylaryl, benzyl optionally substituted with R8, alkanoyl, aroyl optionally substituted with R8; R7 is H, alkyl, alkylaryl, aryl optionally substituted with R8; n is 0-6; A is COOH, or an acid mimic such as tetraazole, SO3H, PO3H2, tetronic acid, etc.; R8 is H, alkyl, cycloalkyl, alkanoyl, halo, OH, perfluoroalkyl, alkoxy, amino, alkylamino, dialkylamino, perfluoroalkoxy; or a pharmaceutically acceptable salt thereof; as well as pharmaceutical compositions and methods of treatment using these compounds.
    Type: Grant
    Filed: July 20, 2004
    Date of Patent: September 6, 2005
    Assignee: Wyeth
    Inventors: Scott Christian Mayer, Eric Gould Gundersen, Hassan Mahmoud Elokdah, David LeRoy Crandall
  • Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor Type-1 (PAI-1)
    Publication number: 20040266733
    Abstract: This invention provides PAI-1 inhibiting compounds of Formula I: 1
    Type: Application
    Filed: July 20, 2004
    Publication date: December 30, 2004
    Applicant: Wyeth
    Inventors: Scott Christian Mayer, Eric Gould Gundersen, Hassan Mahmoud Elokdah, David LeRoy Crandall
  • Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1)
    Patent number: 6800654
    Abstract: This invention provides PAI-1 inhibiting compounds of Formula I: wherein: R1, R2, R3, and R4 are eachH, alkyl,, alkanoyl, halo, OH, aryl optionally substituted with R8, perfluoroalkyl, alkoxy, amino, alkylamino, dialkylamino, perfluoroalkoxy; R5 is H, alkyl, perfluoroalkyl, aryl optionally substituted with R8, alkanoyl, aroyl optionally substituted with R8; R6 is H, alkyl, alkylaryl, benzyl optionally substituted with R8, alkanoyl, aroyl optionally substituted with R8; R7 is H, alkyl, alkylaryl, aryl optionally substituted with R8; n is 0-6; A is COOH, or an acid mimic such as tetraazole, SO3H, PO3H2, tetronic acid, etc.; R8 is H, alkyl, cycloalkyl, alkanoyl, halo, OH, perfluoroalkyl, alkoxy, amino, alkylamino, dialkylamino, perfluoroalkoxy; or a pharmaceutically acceptable salt thereof; as well as pharmaceutical compositions and methods of treatment using these compounds.
    Type: Grant
    Filed: June 13, 2002
    Date of Patent: October 5, 2004
    Assignee: Wyeth
    Inventors: Scott Christian Mayer, Eric Gould Gundersen, Hassan Mahmoud Elokdah, David LeRoy Crandall
  • Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1)
    Publication number: 20030032626
    Abstract: This invention provides PAI-1 inhibiting compounds of Formula I: 1
    Type: Application
    Filed: June 13, 2002
    Publication date: February 13, 2003
    Inventors: Scott Christian Mayer, Eric Gould Gundersen, Hassan Mahmoud Elokdah, David LeRoy Crandall