Patents by Inventor Eric Grovender
Eric Grovender has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200215250Abstract: The invention relates to devices, systems, and methods for calculating a bicarbonate concentration in a fluid used in dialysis. The devices, systems, and methods can be used to calculate the bicarbonate concentration in either dialysate or blood. The invention measures the amount of carbon dioxide in both an acidified and non-acidified solution and calculates the bicarbonate concentration based on the difference in carbon dioxide concentrations.Type: ApplicationFiled: November 22, 2019Publication date: July 9, 2020Inventors: Eric A. Grovender, Thomas E. Meyer, Bryant J. Pudil
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Publication number: 20180221554Abstract: The invention relates to devices, systems, and methods for managing base levels, specifically bicarbonate, in an individual undergoing dialysis. The devices, systems, and methods can be compatible with a sorbent-based dialysis therapy, and open loop control of base levels in the dialysis, without sensors or feedback for controlling the introduction of bicarbonate into the dialysate. The bicarbonate levels can be controlled and personalized to a patient using certain predetermined patient parameters. Related systems, algorithms, and control systems are contemplated including the specific predetermined parameters predictive of post-dialysis bicarbonate levels.Type: ApplicationFiled: January 16, 2018Publication date: August 9, 2018Inventors: Michael J. M. Mazack, Eric A. Grovender, Bryant J. Pudil
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Patent number: 9974896Abstract: Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer of a sorbent material such as zirconium phosphate in a sorbent cartridge. The methods and apparatuses include passing solutions containing combinations of acids, bases and salts through a module containing a rechargeable sorbent material such as zirconium phosphate in order to replace ions bound to the zirconium phosphate with hydrogen and sodium ions. The method allows for a customizable zirconium phosphate, with control over the ratios of sodium to hydrogen on the recharged zirconium phosphate.Type: GrantFiled: March 10, 2015Date of Patent: May 22, 2018Assignee: Medtronic, Inc.Inventors: Bryant J. Pudil, SuPing Lyu, Eric Grovender, Christopher M. Hobot, Martin T. Gerber
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Publication number: 20160032268Abstract: A method for the extraction and purification of urease from jack beans or other natural sources of urease. The method provides an efficient way to obtain purified urease from natural sources. The method can include defatting the natural sources of urease, extracting the urease from impurities, and further purification of the extracted urease.Type: ApplicationFiled: March 4, 2015Publication date: February 4, 2016Applicant: Medtronic, Inc.Inventors: Eric Grovender, Dianne L. Judd, Cindy Roberson, Eric Hall
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Publication number: 20150367055Abstract: Methods and related apparatuses for sorbent recharging are provided. The methods and related apparatuses for recharging can recharge a specific rechargeable layer of a sorbent material such as zirconium phosphate in a sorbent cartridge. The methods and apparatuses include passing solutions containing combinations of acids, bases and salts through a module containing a rechargeable sorbent material such as zirconium phosphate in order to replace ions bound to the zirconium phosphate with hydrogen and sodium ions. The method allows for a customizable zirconium phosphate, with control over the ratios of sodium to hydrogen on the recharged zirconium phosphate.Type: ApplicationFiled: March 10, 2015Publication date: December 24, 2015Applicant: Medtronic, Inc.Inventors: Bryant J. Pudil, SuPing Lyu, Eric Grovender, Christopher M. Hobot, Martin T. Gerber
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Patent number: 9163273Abstract: Embodiments of the invention provide analyte sensors having optimized permselective membranes and methods for making and using such sensors. Embodiments of the invention also provide analyte sensors such as those having porous matrices coated with an analyte sensing composition and methods for making and using such sensors. Illustrative embodiments include electrochemical glucose sensors having glucose oxidase coatings.Type: GrantFiled: May 20, 2010Date of Patent: October 20, 2015Assignee: Medtronic MiniMed, Inc.Inventors: Rajiv Shah, Gopikrishnan Soundararajan, Rebecca K. Gottlieb, Udo Hoss, Eric A. Grovender, Shaun M. Pendo
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Publication number: 20150080844Abstract: Intradermal delivery devices, systems and methods thereof for the administration of a natriuretic or chimeric peptide are described. The described delivery devices, systems and methods provide for the treatment of pathological conditions such as kidney disease alone, heart failure alone, concomitant kidney disease and heart failure, or cardiorenal syndrome by delivery of a natriuretic or chimeric peptide through a microneedle array using a delivery pump. The described delivery devices, systems and methods can provide for greater availability of a natriuretic or chimeric peptide and improved pharmacokinetics.Type: ApplicationFiled: March 15, 2013Publication date: March 19, 2015Applicant: Medtronic, Inc.Inventors: Maura Donovan, William J. L. van Antwerp, Chad A. Wieneke, Mike Kaytor, Eric Grovender
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Patent number: 8523773Abstract: A long term analyte sensor for measuring at least one analyte in the body of a user and which includes a housing, a plurality of analyte contacting sensor elements and at least one structure for relaying information away from the sensor. This plurality of analyte contacting sensor elements are typically disposed in an array. The analyte sensor further includes at least one sensor protection membrane that is controllable in a manner such that sensor elements may be activated (e.g. exposed to the external environment) at different times so as to extend the useful life of the sensor. In illustrative analyte sensors, the analyte is glucose.Type: GrantFiled: July 15, 2009Date of Patent: September 3, 2013Assignee: Medtronic MiniMed, Inc.Inventors: Rajiv Shah, Rebecca K. Gottlieb, Eric A. Grovender, Shaun M. Pendo, Paul Citron, William P. Van Antwerp
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Publication number: 20110184379Abstract: Methods for treating Hepatitis infections are provided. In one embodiment, an initial dosage of interferon is administered to a patient, and interferon serum levels and viral load data is collected over time. This data can be used to determine patient-specific pharmacokinetic and pharmacodynamic parameters and then construct patient-specific interferon delivery profiles. Patient-specific delivery profiles can then be used to design patient-specific therapeutic regimens.Type: ApplicationFiled: March 27, 2009Publication date: July 28, 2011Applicant: MEDTRONIC, INC.Inventors: William P. Van Antwerp, Robert C. Hamlen, Eric A. Grovender
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Publication number: 20110184389Abstract: Apparatuses and methods for pumping fluids such as fluid medications are disclosed. Embodiments of the invention provide an osmotic pump fluid delivery apparatus including elements designed to control the fluid delivery rate. Typical embodiments of the invention include an arrangement of elements such as solute reservoirs that can manipulate the solute concentrations within an inner osmotic compartment or compartments of an osmotic pump so as to control fluid delivery from the pump. Other embodiments include sealed electro-osmotic pumps that do not discharge ions into the surroundings or require water from an external source. These embodiments of the invention provide new ways to control fluid delivery in apparatuses that employ osmotic processes to function.Type: ApplicationFiled: March 31, 2011Publication date: July 28, 2011Applicant: MEDTRONIC, INC.Inventors: Eric A. Grovender, Ashok V. Joshi, John Howard Gordon, Sai Bhavaraju, William P. Van Antwerp
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Publication number: 20110027229Abstract: Methods and systems for treating Hepatitis C infections are provided. Typically the method comprises administering interferon-? to the patient subcutaneously using a continuous infusion apparatus, wherein this therapeutic regimen is sufficient to maintain circulating levels of interferon-? in the serum of the patient above a target concentration for a certain period of time.Type: ApplicationFiled: August 2, 2010Publication date: February 3, 2011Applicant: MEDTRONIC, INC.Inventors: William P. Van Antwerp, Eric A. Grovender, Harry L. A. Janssen, Robert J. De Knegt
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Publication number: 20100331647Abstract: A long term analyte sensor for measuring at least one analyte in the body of a user and which includes a housing, a plurality of analyte contacting sensor elements and at least one structure for relaying information away from the sensor. This plurality of analyte contacting sensor elements are typically disposed in an array. The analyte sensor further includes at least one sensor protection membrane that is controllable in a manner such that sensor elements may be activated (e.g. exposed to the external environment) at different times so as to extend the useful life of the sensor. In illustrative analyte sensors, the analyte is glucose.Type: ApplicationFiled: July 15, 2009Publication date: December 30, 2010Applicant: MEDTRONIC MINIMED, INC.Inventors: Rajiv Shah, Rebecca K. Gottlieb, Eric A. Grovender, Shaun M. Pendo, Paul Citron, William P. Van Antwerp
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Publication number: 20100280347Abstract: Embodiments of the invention provide analyte sensors having optimized permselective membranes and methods for making and using such sensors. Embodiments of the invention also provide analyte sensors such as those having porous matrices coated with an analyte sensing composition and methods for making and using such sensors. Illustrative embodiments include electrochemical glucose sensors having glucose oxidase coatings.Type: ApplicationFiled: May 20, 2010Publication date: November 4, 2010Applicant: MEDTRONIC MINIMED, INC.Inventors: Rajiv Shah, Gopikrishnan Soundararajan, Rebecca K. Gottlieb, Udo Hoss, Eric A. Grovender, Shaun M. Pendo
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Publication number: 20100279377Abstract: Embodiments of the invention provide analyte sensors having optimized permselective membranes and methods for making and using such sensors. Embodiments of the invention also provide analyte sensors such as those having porous matrices coated with an analyte sensing composition and methods for making and using such sensors. Illustrative embodiments include electrochemical glucose sensors having glucose oxidase coatings.Type: ApplicationFiled: May 20, 2010Publication date: November 4, 2010Applicant: MEDTRONIC MINIMED, INC.Inventors: Rajiv Shah, Gopikrishnan Soundararajan, Rebecca K. Gottlieb, Udo Hoss, Eric A. Grovender, Shaun M. Pendo
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Patent number: 7813780Abstract: Embodiments of the invention provide analyte sensors having optimized permselective membranes and methods for making and using such sensors. Embodiments of the invention also provide analyte sensors such as those having porous matrices coated with an analyte sensing composition and methods for making and using such sensors. Illustrative embodiments include electrochemical glucose sensors having glucose oxidase coatings.Type: GrantFiled: December 13, 2005Date of Patent: October 12, 2010Assignee: Medtronic MiniMed, Inc.Inventors: Rajiv Shah, Gopikrishnan Soundararajan, Rebecca K. Gottlieb, Udo Hoss, Eric A. Grovender, Shaun M. Pendo
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Publication number: 20100196439Abstract: Various methods and devices are provided for providing therapy to a living body. In one embodiment, an implanted permeable container has living cells provided therein, and various nutrients and/or agents are provided into the container to promote cell life.Type: ApplicationFiled: December 20, 2007Publication date: August 5, 2010Applicant: Medtronic, Inc.Inventors: Michael Theodore Beck, Deon Bezuidenhout, Kelvin Bonnema, Kimberly A. Chaffin, Neil Davies, Brian C.A. Fernandes, Eric J. Fogt, Eric A. Grovender, Robert Cushing Hamlen, Matthew Jolly, Eamonn J. McAndrew, Syamasundar V. Pakala, William P. VanAntwerp, Peter P. Zilla, Edouard A. Koullick
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Publication number: 20090281528Abstract: Apparatuses and methods for pumping fluids such as fluid medications are disclosed. In illustrative embodiments of the invention, the architectural geometry of one or more fluid containing chambers within a fluid delivery device is constructed to incorporate design parameters that function to control movement of fluids within the device. Typical embodiments of the invention provide osmotic pumps that use such elements to control various fluid delivery parameters.Type: ApplicationFiled: May 12, 2009Publication date: November 12, 2009Applicant: MEDTRONIC, INC.Inventors: Eric A. Grovender, John H. Gordon, William P. Van Antwerp
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Patent number: 7577470Abstract: A long term analyte sensor for measuring at least one analyte in the body of a user and which includes a housing, a plurality of analyte contacting sensor elements and at least one structure for relaying information away from the sensor. This plurality of analyte contacting sensor elements are typically disposed in an array. The analyte sensor further includes at least one sensor protection membrane that is controllable in a manner such that sensor elements may be activated (e.g. exposed to the external environment) at different times so as to extend the useful life of the sensor. In illustrative analyte sensors, the analyte is glucose.Type: GrantFiled: November 15, 2004Date of Patent: August 18, 2009Assignee: Medtronic MiniMed, Inc.Inventors: Rajiv Shah, Rebecca K. Gottlieb, Eric A. Grovender, Shaun Pendo, Paul Citron, William P. Van Antwerp
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Publication number: 20080102119Abstract: Apparatuses and methods for pumping fluids such as fluid medications are disclosed. Embodiments of the invention provide an osmotic pump fluid delivery apparatus including elements designed to control the fluid delivery rate. Typical embodiments of the invention include an arrangement of elements such as solute reservoirs that can manipulate the solute concentrations within an inner osmotic compartment or compartments of an osmotic pump so as to control fluid delivery from the pump. Other embodiments include sealed electro-osmotic pumps that do not discharge ions into the surroundings or require water from an external source. These embodiments of the invention provide new ways to control fluid delivery in apparatuses that employ osmotic processes to function.Type: ApplicationFiled: November 1, 2006Publication date: May 1, 2008Inventors: Eric A. Grovender, Ashok V. Joshi, John Howard Gordon, Sai Bhavaraju, William P. Van Antwerp
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Publication number: 20070135698Abstract: Embodiments of the invention provide analyte sensors having optimized permselective membranes and methods for making and using such sensors. Embodiments of the invention also provide analyte sensors such as those having porous matrices coated with an analyte sensing composition and methods for making and using such sensors. Illustrative embodiments include electrochemical glucose sensors having glucose oxidase coatings.Type: ApplicationFiled: December 13, 2005Publication date: June 14, 2007Inventors: Rajiv Shah, Gopikrishnan Soundararajan, Rebecca Gottlieb, Udo Hoss, Eric Grovender, Shaun Pendo