Patents by Inventor Eric H. Kawashima
Eric H. Kawashima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9902951Abstract: A nucleic acid molecule can be annealed to an appropriate immobilized primer. The primer can then be extended and the molecule and the primer can be separated from one another. The extended primer can then be annealed to another immobilized primer and the other primer can be extended. Both extended primers can then be separated from one another and can be used to provide further extended primers. The process can be repeated to provide amplified, immobilized nucleic acid molecules. These can be used for many different purposes, including sequencing, screening, diagnosis, in situ nucleic acid synthesis, monitoring gene expression, nucleic acid fingerprinting, etc.Type: GrantFiled: May 2, 2013Date of Patent: February 27, 2018Assignees: Illumina, Inc., Illumina Cambridge LimitedInventors: Eric H. Kawashima, Laurent Farinelli, Pascal Mayer
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Patent number: 9593328Abstract: A nucleic acid molecule can be annealed to an appropriate immobilized primer. The primer can then be extended and the molecule and the primer can be separated from one another. The extended primer can then be annealed to another immobilized primer and the other primer can be extended. Both extended primers can then be separated from one another and can be used to provide further extended primers. The process can be repeated to provide amplified, immobilized nucleic acid molecules. These can be used for many different purposes, including sequencing, screening, diagnosis, in situ nucleic acid synthesis, monitoring gene expression, nucleic acid fingerprinting, etc.Type: GrantFiled: January 20, 2015Date of Patent: March 14, 2017Assignee: Illumina, Inc.Inventors: Eric H. Kawashima, Laurent Farinelli, Pascal Mayer
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Publication number: 20150133320Abstract: A nucleic acid molecule can be annealed to an appropriate immobilized primer. The primer can then be extended and the molecule and the primer can be separated from one another. The extended primer can then be annealed to another immobilized primer and the other primer can be extended. Both extended primers can then be separated from one another and can be used to provide further extended primers. The process can be repeated to provide amplified, immobilized nucleic acid molecules. These can be used for many different purposes, including sequencing, screening, diagnosis, in situ nucleic acid synthesis, monitoring gene expression, nucleic acid fingerprinting, etc.Type: ApplicationFiled: January 20, 2015Publication date: May 14, 2015Applicant: ILLUMINA, INC.Inventors: Eric H. Kawashima, Laurent Farinelli, Pascal Mayer
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Patent number: 8993271Abstract: A nucleic acid molecule can be annealed to an appropriate immobilized primer. The primer can then be extended and the molecule and the primer can be separated from one another. The extended primer can then be annealed to another immobilized primer and the other primer can be extended. Both extended primers can then be separated from one another and can be used to provide further extended primers. The process can be repeated to provide amplified, immobilized nucleic acid molecules. These can be used for many different purposes, including sequencing, screening, diagnosis, in situ nucleic acid synthesis, monitoring gene expression, nucleic acid fingerprinting, etc.Type: GrantFiled: March 14, 2013Date of Patent: March 31, 2015Assignee: Illumina, Inc.Inventors: Eric H. Kawashima, Laurent Farinelli, Pascal Mayer
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Publication number: 20150087531Abstract: A nucleic acid molecule can be annealed to an appropriate immobilized primer. The primer can then be extended and the molecule and the primer can be separated from one another. The extended primer can then be annealed to another immobilized primer and the other primer can be extended. Both extended primers can then be separated from one another and can be used to provide further extended primers. The process can be repeated to provide amplified, immobilized nucleic acid molecules. These can be used for many different purposes, including sequencing, screening, diagnosis, in situ nucleic acid synthesis, monitoring gene expression, nucleic acid fingerprinting, etc.Type: ApplicationFiled: November 26, 2014Publication date: March 26, 2015Inventors: Eric H. Kawashima, Laurent Farinelli, Pascal Mayer
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Publication number: 20140371100Abstract: A nucleic acid molecule can be annealed to an appropriate immobilized primer. The primer can then be extended and the molecule and the primer can be separated from one another. The extended primer can then be annealed to another immobilized primer and the other primer can be extended. Both extended primers can then be separated from one another and can be used to provide further extended primers. The process can be repeated to provide amplified, immobilized nucleic acid molecules. These can be used for many different purposes, including sequencing, screening, diagnosis, in situ nucleic acid synthesis, monitoring gene expression, nucleic acid fingerprinting, etc.Type: ApplicationFiled: August 21, 2014Publication date: December 18, 2014Inventors: Eric H. Kawashima, Laurent Farinelli, Pascal Mayer
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Publication number: 20130231254Abstract: A nucleic acid molecule can be annealed to an appropriate immobilized primer. The primer can then be extended and the molecule and the primer can be separated from one another. The extended primer can then be annealed to another immobilized primer and the other primer can be extended. Both extended primers can then be separated from one another and can be used to provide further extended primers. The process can be repeated to provide amplified, immobilized nucleic acid molecules. These can be used for many different purposes, including sequencing, screening, diagnosis, in situ nucleic acid synthesis, monitoring gene expression, nucleic acid fingerprinting, etc.Type: ApplicationFiled: May 2, 2013Publication date: September 5, 2013Applicant: ILLUMINA, INC.Inventors: Eric H. Kawashima, Laurent Farinelli, Pascal Mayer
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Publication number: 20130217586Abstract: A nucleic acid molecule can be annealed to an appropriate immobilized primer. The primer can then be extended and the molecule and the primer can be separated from one another. The extended primer can then be annealed to another immobilized primer and the other primer can be extended. Both extended primers can then be separated from one another and can be used to provide further extended primers. The process can be repeated to provide amplified, immobilized nucleic acid molecules. These can be used for many different purposes, including sequencing, screening, diagnosis, in situ nucleic acid synthesis, monitoring gene expression, nucleic acid fingerprinting, etc.Type: ApplicationFiled: March 14, 2013Publication date: August 22, 2013Applicant: ILLUMINA CAMBRIDGE LIMITEDInventors: Eric H. Kawashima, Laurent Farinelli, Pascal Mayer
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Patent number: 8476044Abstract: A nucleic acid molecule can be annealed to an appropriate immobilized primer. The primer can then be extended and the molecule and the primer can be separated from one another. The extended primer can then be annealed to another immobilized primer and the other primer can be extended. Both extended primers can then be separated from one another and can be used to provided further extended primers. The process can be repeated to provide amplified, immobilized nucleic acid molecules. These can be used for many different purposes, including sequencing, screening, diagnosis, in situ nucleic acid synthesis, monitoring gene expression, nucleic acid fingerprinting, etc.Type: GrantFiled: April 16, 2008Date of Patent: July 2, 2013Assignee: Illumina, Inc.Inventors: Pascal Mayer, Laurent Farinelli, Eric H. Kawashima
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Patent number: 8143008Abstract: A nucleic acid molecule can be annealed to an appropriate immobilized primer. The primer can then be extended and the molecule and the primer can be separated from one another. The extended primer can then be annealed to another immobilized primer and the other primer can be extended. Both extended primers can then be separated from one another and can be used to provide further extended primers. The process can be repeated to provide amplified, immobilized nucleic acid molecules. These can be used for many different purposes, including sequencing, screening, diagnosis, in situ nucleic acid synthesis, monitoring gene expression, nucleic acid fingerprinting, etc.Type: GrantFiled: April 30, 2010Date of Patent: March 27, 2012Assignee: Illumina, Inc.Inventors: Eric H. Kawashima, Laurent Farinelli, Pascal Mayer
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Patent number: 7985565Abstract: A nucleic acid molecule can be annealed to an appropriate immobilized primer. The primer can then be extended and the molecule and the primer can be separated from one another. The extended primer can then be annealed to another immobilized primer and the other primer can be extended. Both extended primers can then be separated from one another and can be used to provided further extended primers. The process can be repeated to provide amplified, immobilized nucleic acid molecules. These can be used for many different purposes, including sequencing, screening, diagnosis, in situ nucleic acid synthesis, monitoring gene expression, nucleic acid fingerprinting, etc.Type: GrantFiled: June 2, 2003Date of Patent: July 26, 2011Assignee: Illumina, Inc.Inventors: Pascal Mayer, Laurent Farinelli, Eric H. Kawashima
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Publication number: 20110045541Abstract: A nucleic acid molecule can be annealed to an appropriate immobilised primer. The primer can then be extended and the molecule and the primer can be separated from one another. The extended primer can then be annealed to another immobilised primer and the other primer can be extended. Both extended primers can then be separated from one another and can be used to provide further extended primers. The process can be repeated to provide amplified, immobilised nucleic acid molecules. These can be used for many different purposes, including sequencing, screening, diagnosis, in situ nucleic acid synthesis, monitoring gene expression, nucleic acid fingerprinting, etc.Type: ApplicationFiled: April 30, 2010Publication date: February 24, 2011Applicants: ILLUMINA CAMBRIDGE, LTD., ILLUMINA, INC.Inventors: Eric H. Kawashima, Laurent Farinelli, Pascal Mayer
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Publication number: 20080286795Abstract: A nucleic acid molecule can be annealed to an appropriate immobilized primer. The primer can then be extended and the molecule and the primer can be separated from one another. The extended primer can then be annealed to another immobilized primer and the other primer can be extended. Both extended primers can then be separated from one another and can be used to provided further extended primers. The process can be repeated to provide amplified, immobilized nucleic acid molecules. These can be used for many different purposes, including sequencing, screening, diagnosis, in situ nucleic acid synthesis, monitoring gene expression, nucleic acid fingerprinting, etc.Type: ApplicationFiled: April 15, 2008Publication date: November 20, 2008Applicant: Solexa LimitedInventors: Eric H. Kawashima, Laurent Farinelli, Pascal Mayer
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Publication number: 20020055100Abstract: Different nucleic acid molecules present at different locations can be sequenced in parallel Primers that are annealed to the nucleic acid molecules can be provided. Each location can then be provided with a nucleic acid polymerase and a nucleotide. It can then be determined whether or not the nucleotide has been used in primer extension and the process can be repeated. As an alternative to using primers, a nick in a double stranded nucleic acid molecule can provide a 3′-OH group for chain extension.Type: ApplicationFiled: September 30, 1999Publication date: May 9, 2002Inventors: ERIC H. KAWASHIMA, LAURENT FARINELLI, PASCAL MAYER
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Patent number: 5487984Abstract: A process of producing mammalian tumor necrosis factors (TNF) and TNF-like polypeptides by culturing eukaryotic or prokaryotic hosts transformed with DNA sequences encoding those polypeptides. A process for purifying TNF-like polypeptides using an anion exchanger. The TNFs and TNF-like polypeptides produced by the processes of this invention, and compositions and methods utilizing those TNFs and TNF-like polypeptides, are useful in anticancer, antitumor and antimalarial therapies. They are also useful together with interferon therapy, chemotherapy in anticancer and antitumor therapies, and in combination with actinomycin D in the treatment of tumor-bearing mammals.Type: GrantFiled: December 20, 1985Date of Patent: January 30, 1996Assignee: Biogen, Inc.Inventors: Bernard Allet, Eric H. Kawashima
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Patent number: 5182196Abstract: Recombinant DNA molecules comprising DNA sequences derived from bacteriophage T4 that are useful in expressing desired polypeptides in unexpectedly high yields, hosts and expression systems comprising such recombinant DNA molecules and methods for expressing desired polypeptides in high yields by the utilization of such hosts and expression systems.Type: GrantFiled: June 27, 1989Date of Patent: January 26, 1993Assignee: Biogen, Inc.Inventors: Bernard Allet, Eric H. Kawashima