Abstract: Disclosed is a device for extraction of a resected tissue or the like from a body comprising an elongate portion having a rounded end; a sleeve assembly comprising an anchor portion for contacting a region around the resected tissue when inflated, and a body portion shaped and dimensioned to receive the resected tissue; the body portion comprises a first end, a second end and a pliable sleeve; the first end and the second end each having a respective diameter greater than a desired diameter of the natural orifice or a tissue opening; wherein the pliable sleeve is disposed between the first end and the second end in a manner which a distance between the first end and the second end is adjustable.

Abstract: A suture clip applier for applying a suture around a tubular tissue adjacent to an open lumen. The suture clip applier includes an elongated body having a tissue clinching mechanism at one end of the body. The tissue clinching mechanism comprises two arms that are movable between open and clinched positions. The suture clip applier includes a plurality of deformable suture clips mounted along a longitudinal length of the elongated body, wherein each suture clip is configured to be detachably positioned within an interior of the two arms and to be deformed between open and clinched positions in response to the two arms being moved between the open and clinched positions. The suture clip applier further includes a length of suture comprising a pre-formed adjustable fastening and a loop extending from the pre-formed adjustable fastening, the loop extending between the two arms.

Abstract: Polymeric particles and scaffolds containing anesthetic agents, their use for sustained local delivery of anesthetic agents, reduction of pain killer addiction and addiction risk, and methods of fabricating and administering polymeric particles containing anesthetic agents are described herein.

Abstract: Polymeric particles and scaffolds containing anesthetic agents, their use for sustained local delivery of anesthetic agents, reduction of pain killer addiction and addiction risk, and methods of fabricating and administering polymeric particles containing anesthetic agents are described herein.

Abstract: Disclosed is a device for extraction of a resected tissue or the like from a body comprising an elongate portion having a rounded end; a sleeve assembly comprising an anchor portion for contacting a region around the resected tissue when inflated, and a body portion shaped and dimensioned to receive the resected tissue; the body portion comprises a first end, a second end and a pliable sleeve; the first end and the second end each having a respective diameter greater than a desired diameter of the natural orifice or a tissue opening; wherein the pliable sleeve is disposed between the first end and the second end in a manner which a distance between the first end and the second end is adjustable.

Abstract: Polymeric particles and scaffolds containing anesthetic agents, their use for sustained local delivery of anesthetic agents, reduction of pain killer addiction and addiction risk, and methods of fabricating and administering polymeric particles containing anesthetic agents are described herein.

Abstract: The present disclosure provides polymeric particles and scaffolds comprising a matrix and an anesthetic agent. In one embodiment, the matrix comprises a bioerodible polymer. The disclosure further relates to the use of the polymeric particles and scaffolds for sustained local delivery of anesthetic agents, reduction of pain killer addiction and addiction risk. The disclosure also provides methods of fabricating and administering polymeric particles and scaffolds containing an anesthetic agent described herein.

Abstract: A suture clip applier for applying a suture around a tubular tissue adjacent to an open lumen. The suture clip applier includes an elongated body having a tissue clinching mechanism at one end of the body. The tissue clinching mechanism comprises two arms that are movable between open and clinched positions. The suture clip applier includes a plurality of deformable suture clips mounted along a longitudinal length of the elongated body, wherein each suture clip is configured to be detachably positioned within an interior of the two arms and to be deformed between open and clinched positions in response to the two arms being moved between the open and clinched positions. The suture clip applier further includes a length of suture comprising a pre-formed adjustable fastening and a loop extending from the pre-formed adjustable fastening, the loop extending between the two arms.

Abstract: Polymeric particles and scaffolds containing anesthetic agents, their use for sustained local delivery of anesthetic agents, reduction of pain killer addiction and addiction risk, and methods of fabricating and administering polymeric particles containing anesthetic agents are described herein.