Patents by Inventor Eric Hein

Eric Hein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230002450
    Abstract: Therapeutic polypeptides, compositions thereof and methods of use thereof for activating NK cells and treating tumors are provided. The therapeutic polypeptides can include a first domain for binding NKG2D and a second domain for binding a tumor target.
    Type: Application
    Filed: February 18, 2020
    Publication date: January 5, 2023
    Inventors: Alexander Sasha KRUPNICK, Eric Reed LAZEAR, Sarah HEIN, Daniel Marvin WATKINS
  • Publication number: 20230003160
    Abstract: A mixer comprises a tubular housing defining a longitudinal axis along which exhaust gas flows. Injected reductant flows along an injection axis that extends at a non-parallel angle to the longitudinal axis. A first flow guide element extends across and blocks a portion of the tubular housing and includes a first aperture extending therethrough. The first flow guide element is positioned upstream from the reductant inlet such that exhaust gas flowing through the first aperture is impinged by the reductant. A second flow guide element is positioned downstream from the first flow guide element and fixed to the first flow guide element to define a mixing chamber in which injected reductant and exhaust gas mix. An intermediate wall is integrally formed with one of the first and second flow guide elements. The other of the first and second flow guide elements is fixed to the intermediate wall.
    Type: Application
    Filed: September 7, 2022
    Publication date: January 5, 2023
    Inventors: Sascha HAVERKAMP, Joachim GEHRLEIN, Stefan KOHRS, Eric A. HEIN, Attila KOVACS
  • Patent number: 11506099
    Abstract: An exhaust treatment assembly for receiving exhaust gas from a motor vehicle includes a mix pipe, a sheath, and a heater. The mix pipe at least partially defines a passage adapted to receive the exhaust gas and a chemical reductant. The sheath includes a first end fluidly sealed to the mix pipe. At least a portion of the sheath is radially spaced apart from the mix pipe to at least partially define a gap. The heater is disposed in the gap. The heater is adapted to heat a reductant impingement surface.
    Type: Grant
    Filed: August 24, 2021
    Date of Patent: November 22, 2022
    Assignees: Tenneco Automotive Operating Company Inc., Tenneco GmbH
    Inventors: Thomas M. Harris, Eric A. Hein
  • Publication number: 20220323541
    Abstract: Compositions and methods for treatment of autoimmune and inflammatory conditions which include Orthopox Major Histocompatibility complex (MHC) class I-like protein (OMCP) or a variant thereof.
    Type: Application
    Filed: August 13, 2020
    Publication date: October 13, 2022
    Applicant: COURIER THERAPEUTICS, INC.
    Inventors: Alexander Sasha KRUPNICK, Eric Reed LAZEAR, Sarah HEIN, Daniel Marvin WATKINS
  • Patent number: 11466606
    Abstract: A mixer assembly for mixing an injected reductant with an exhaust gas comprises a tubular housing including a reductant inlet, an exhaust gas inlet and an exhaust gas outlet. The reductant inlet is positioned on a first side of the tubular housing and oriented to direct injected reductant along an injection access that extends transversely to a longitudinal axis. A first flow guide element is shaped as a sheet including a first aperture extending therethrough as well as a surface facing upstream. Exhaust gas flowing through the first aperture is impinged by the injected redundant. A second flow guide element is shaped as a sheet, positioned downstream from the first flow guide element and fixed to the first flow guide element to define a mixing chamber between the first flow guide element and the second flow guide element in which the injected redundant and the exhaust gas mix.
    Type: Grant
    Filed: April 29, 2021
    Date of Patent: October 11, 2022
    Assignee: Tenneco GmbH
    Inventors: Sascha Haverkamp, Joachim Gehrlein, Stefan Kohrs, Eric A. Hein, Attila Kovacs
  • Publication number: 20220229634
    Abstract: A photonic processor uses light signals and a residue number system (RNS) to perform calculations. The processor sums two or more values by shifting the phase of a light signal with phase shifters and reading out the summed phase with a coherent detector. Because phase winds back every 2? radians, the photonic processor performs addition modulo 2?. A photonic processor may use the summation of phases to perform dot products and correct erroneous residues. A photonic processor may use the RNS in combination with a positional number system (PNS) to extend the numerical range of the photonic processor, which may be used to accelerate homomorphic encryption (HE)-based deep learning.
    Type: Application
    Filed: December 6, 2021
    Publication date: July 21, 2022
    Applicant: Lightmatter, Inc.
    Inventors: Eric Hein, Ayon Basumallik, Nicholas C. Harris, Darius Bunandar, Cansu Demirkiran
  • Publication number: 20210290288
    Abstract: Multi-electrode ablation systems, methods, and controllers are described. In one example, a method of beginning an ablation procedure using a multi-electrode ablation system is described. The method includes selectively coupling the output of a power supply to a first electrode of a plurality of electrodes to increase a temperature at the first electrode to a first temperature set-point and limit a rate of increase of the temperature at the first electrode to a predetermined first rate.
    Type: Application
    Filed: June 10, 2021
    Publication date: September 23, 2021
    Inventors: John B. Blix, James C. Baker, Kevin K. Ennett, John Eric Hein, Joseph Allen Brotz, Joseph William Barnier, Raymond Vincent Froehlich, Michael Olsen, Sukanya Varadharajan, Catherine A. Pipenhagen
  • Publication number: 20210246820
    Abstract: A mixer assembly for mixing an injected reductant with an exhaust gas comprises a tubular housing including a reductant inlet, an exhaust gas inlet and an exhaust gas outlet. The reductant inlet is positioned on a first side of the tubular housing and oriented to direct injected reductant along an injection access that extends transversely to a longitudinal axis. A first flow guide element is shaped as a sheet including a first aperture extending therethrough as well as a surface facing upstream. Exhaust gas flowing through the first aperture is impinged by the injected redundant. A second flow guide element is shaped as a sheet, positioned downstream from the first flow guide element and fixed to the first flow guide element to define a mixing chamber between the first flow guide element and the second flow guide element in which the injected redundant and the exhaust gas mix.
    Type: Application
    Filed: April 29, 2021
    Publication date: August 12, 2021
    Inventors: Sascha HAVERKAMP, Joachim GEHRLEIN, Stefan KOHRS, Eric A. HEIN, Attila KOVACS
  • Patent number: 11058474
    Abstract: Multi-electrode ablation systems, methods, and controllers are described. In one example, a method of beginning an ablation procedure using a multi-electrode ablation system is described. The method includes selectively coupling the output of a power supply to a first electrode of a plurality of electrodes to increase a temperature at the first electrode to a first temperature set-point and limit a rate of increase of the temperature at the first electrode to a predetermined first rate.
    Type: Grant
    Filed: August 28, 2017
    Date of Patent: July 13, 2021
    Assignee: ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
    Inventors: John B. Blix, James C. Baker, Kevin K. Ennett, John Eric Hein, Joseph Allen Brotz, Joseph William Barnier, Raymond Vincent Froehlich, Michael Olsen, Sukanya Varadharajan, Catherine A. Pipenhagen
  • Patent number: 10995643
    Abstract: A mixer assembly comprises a tubular housing including a reductant inlet, an exhaust gas inlet and an exhaust gas outlet. The tubular housing defines a longitudinal axis along which exhaust enters the housing. The reductant inlet is positioned on a first side of the tubular housing. An upstream element covers approximately one-half of the cross sectional area of the enhaust gas inlet and is positioned upstream of the reductant inlet. An upstream surface of the upstream mixing element directs exhaust gas flow transversly toward the reductant inlet. A downstream mixing element along with the upstream mixing element at least partially defines a reductant receiving duct in which injected reductant and exhaust gas mix.
    Type: Grant
    Filed: March 19, 2019
    Date of Patent: May 4, 2021
    Inventors: Sascha Haverkamp, Joachim Gehrlein, Stefan Kohrs, Eric A. Hein, Attila Kovacs
  • Patent number: 10918434
    Abstract: Multi-electrode ablation systems, methods, and controllers are described. In one example, a multi-electrode ablation system includes a power supply configured to be coupled to a plurality of electrodes and a controller coupled to the power supply. The controller is configured to determine a thermal gain of each electrode of the plurality of electrodes. For each electrode of the plurality of electrodes, the controller sets a power limit based at least in part on said electrode's determined thermal gain. The power limit establishes a maximum power that may be dissipated through said electrode.
    Type: Grant
    Filed: May 3, 2018
    Date of Patent: February 16, 2021
    Assignee: ST. JUDE MEDICAL, CARDIOLOGY DIVISION, INC.
    Inventors: John B. Blix, James C. Baker, Kevin K. Ennett, John Eric Hein, Joseph Allen Brotz, Joseph William Barnier, Raymond Victor Froehlich, Michael Olsen, Sukanya Varadharajan
  • Patent number: 10711677
    Abstract: A mixer assembly for mixing an injected reductant with an exhaust gas output from a combustion engine comprises a mixer housing including a wall defining an exhaust passageway having a longitudinal axis. A tubular swirling device housing extends along a first axis substantially transverse to the longitudinal axis. The tubular swirling device includes a plurality of openings through which exhaust gas enters. The exhaust gas within the tubular swirling device swirls about the first axis and exits at an outlet end of the tubular swirling device. A mixing plate is positioned immediately downstream of the tubular swirling device. The mixing plate swirls the exhaust about a second axis extending parallel to the longitudinal axis.
    Type: Grant
    Filed: March 19, 2019
    Date of Patent: July 14, 2020
    Assignee: Tenneco Automotive Operating Company Inc.
    Inventors: Lawrence J. Noren, IV, Daniel J. Owen, Jeffrey W. Denton, Attila Kovacs, Eric A. Hein, Meng-Huang Lu, Manoj K. Sampath
  • Patent number: 10480372
    Abstract: The disclosure refers to a static mixer for use in an exhaust system for a combustion engine and for the mixing of an additive injected into an exhaust system. The mixer consists of a tubular housing encircling a central axis X. The housing comprises an input opening at the end in the direction of central axis X and at the opposite end an outlet opening, whereby the inlet opening is used for the supply of additive injected into the exhaust system. The housing is closed in the section of the inlet opening and in the section of the outlet opening in circumferential direction around the central axis X. The static mixer is designed to generate little counterpressure, to guarantee rapid and complete reducing agent preparation and at the same time to be resistant to production tolerances.
    Type: Grant
    Filed: May 30, 2016
    Date of Patent: November 19, 2019
    Inventors: Tobias Inclán, Thomas Kremer, Eric Hein
  • Patent number: 10458302
    Abstract: An exhaust aftertreatment system may include a reductant tank, a gaseous ammonia source, an injector, first conduit and a second conduit. The injector may receive the liquid reductant from the reductant tank and the gaseous ammonia from the gaseous ammonia source and inject the liquid reductant into a stream of exhaust gas in a first mode, inject the gaseous ammonia into the stream of exhaust gas in a second mode, and both the liquid reductant and the gaseous ammonia into the stream of exhaust gas in a third mode. The first conduit may communicate liquid reductant from the reductant tank to the injector. The second conduit may communicate gaseous ammonia from the gaseous ammonia source to the injector.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: October 29, 2019
    Assignees: Tenneco Automotive Operating Company Inc., Tenneco GmbH
    Inventors: Mark Devito, Ryan A. Floyd, Adam J. Kotrba, Padmanabha R. Ettireddy, Michael C. Bradford, Bradley Fingland, John W. Degeorge, Philipp Kreutziger, Manuel Kluck, Michael Flockert, Mathias Hund, Eric A. Hein
  • Patent number: 10427099
    Abstract: A mixing system for an exhaust system includes a first mixing device having a plurality of first auger blades and an inlet having a first cross-sectional area. A second mixing device is separate and downstream from the first mixing device and includes a second auger blade. The second mixing device includes an inlet having a second cross-sectional area greater than the first cross-sectional area. A flow path longitudinal centerline of the first mixing device extends at an angle to a flow path longitudinal centerline of the second mixing device. A flow path longitudinal centerline of the first mixing device intersects the second auger blade. The first mixing device is disposed within a first portion of an exhaust pipe and the second mixing device is disposed in a second portion of the exhaust pipe. The second portion has a larger cross-sectional area than the first portion.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: October 1, 2019
    Assignee: Tenneco Automotive Operating Company Inc.
    Inventors: Jeffrey W. Denton, Eric A. Hein, Attila Kovacs, Kevin R. Reeder, Jonar Mendoza, Gary R. Moore, Manoj K. Sampath, John R. Hardin
  • Publication number: 20190211733
    Abstract: A mixer assembly for mixing an injected reductant with an exhaust gas output from a combustion engine comprises a mixer housing including a wall defining an exhaust passageway having a longitudinal axis. A tubular swirling device housing extends along a first axis substantially transverse to the longitudinal axis. The tubular swirling device includes a plurality of openings through which exhaust gas enters. The exhaust gas within the tubular swirling device swirls about the first axis and exits at an outlet end of the tubular swirling device. A mixing plate is positioned immediately downstream of the tubular swirling device. The mixing plate swirls the exhaust about a second axis extending parallel to the longitudinal axis.
    Type: Application
    Filed: March 19, 2019
    Publication date: July 11, 2019
    Inventors: Lawrence J. NOREN, IV, Daniel J. OWEN, Jeffrey W. DENTON, Attila KOVACS, Eric A. HEIN, Meng-Huang LU, Manoj K. SAMPATH
  • Publication number: 20190211732
    Abstract: A mixer assembly comprises a tubular housing including a reductant inlet, an exhaust gas inlet and an exhaust gas outlet. The tubular housing defines a longitudinal axis along which exhaust enters the housing. The reductant inlet is positioned on a first side of the tubular housing. An upstream element covers approximately one-half of the cross sectional area of the enhaust gas inlet and is positioned upstream of the reductant inlet. An upstream surface of the upstream mixing element directs exhaust gas flow transversly toward the reductant inlet. A downstream mixing element along with the upstream mixing element at least partially defines a reductant receiving duct in which injected reductant and exhaust gas mix.
    Type: Application
    Filed: March 19, 2019
    Publication date: July 11, 2019
    Inventors: Sascha HAVERKAMP, Joachim GEHRLEIN, Stefan KOHRS, Eric A. HEIN, Attila KOVACS
  • Patent number: 10273855
    Abstract: A mixer assembly for mixing an injected reductant with an exhaust gas output from a combustion engine comprises a mixer housing including a wall defining an exhaust passageway having a longitudinal axis. A tubular swirling device housing extends along a first axis substantially transverse to the longitudinal axis. The tubular swirling device includes a plurality of openings through which exhaust gas enters. The exhaust gas within the tubular swirling device swirls about the first axis and exits at an outlet end of the tubular swirling device. A mixing plate is positioned immediately downstream of the tubular swirling device. The mixing plate swirls the exhaust about a second axis extending parallel to the longitudinal axis.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: April 30, 2019
    Assignee: Tenneco Automotive Operating Company Inc.
    Inventors: Lawrence J. Noren, IV, Daniel J. Owen, Jeffrey W. Denton, Attila Kovacs, Eric A. Hein, Meng-Huang Lu, Manoj K. Sampath
  • Publication number: 20190022583
    Abstract: A mixing system for an exhaust system includes a first mixing device having a plurality of first auger blades and an inlet having a first cross-sectional area. A second mixing device is separate and downstream from the first mixing device and includes a second auger blade. The second mixing device includes an inlet having a second cross-sectional area greater than the first cross-sectional area. A flow path longitudinal centerline of the first mixing device extends at an angle to a flow path longitudinal centerline of the second mixing device. A flow path longitudinal centerline of the first mixing device intersects the second auger blade. The first mixing device is disposed within a first portion of an exhaust pipe and the second mixing device is disposed in a second portion of the exhaust pipe. The second portion has a larger cross-sectional area than the first portion.
    Type: Application
    Filed: September 26, 2018
    Publication date: January 24, 2019
    Inventors: Jeffrey W. DENTON, Eric A. HEIN, Attila KOVACS, Kevin R. REEDER, Jonar MENDOZA, Gary R. MOORE, Manoj K. SAMPATH, John R. HARDIN
  • Publication number: 20180298802
    Abstract: A mixer assembly for mixing an injected reductant with an exhaust gas output from a combustion engine comprises a mixer housing including a wall defining an exhaust passageway having a longitudinal axis. A tubular swirling device housing extends along a first axis substantially transverse to the longitudinal axis. The tubular swirling device includes a plurality of openings through which exhaust gas enters. The exhaust gas within the tubular swirling device swirls about the first axis and exits at an outlet end of the tubular swirling device. A mixing plate is positioned immediately downstream of the tubular swirling device. The mixing plate swirls the exhaust about a second axis extending parallel to the longitudinal axis.
    Type: Application
    Filed: June 21, 2018
    Publication date: October 18, 2018
    Inventors: Lawrence J. NOREN, IV, Daniel J. OWEN, Jeffrey W. DENTON, Attila KOVACS, Eric A. HEIN, Meng-Huang LU, Manoj K. SAMPATH