Abstract: The present invention relates to compounds and methods which may be useful as treatments of diseases.

Abstract: A method and a bale wrapping device for wrapping a bale. The method includes receiving a bale at a bale moving ramp device of the bale wrapping device. The bale on the bale moving ramp device is moved through a bale wrapping frame. The breathable sheet of wrapping material is applied on the bale to wrap the bale as the bale passes through the bale wrapping frame, and a roller on the bale wrapping frame holds a roll of the breathable sheet of wrapping material.

Abstract: A pressure controller for a fluidic bladder has in sequence a pump, a first fluid line, a supply pressure sensor, a second fluid line, a bladder having an inlet coupled to the second fluid line, a bladder outlet coupled to a third fluid line of substantially equal length to the second fluid line, a return pressure sensor, and a fourth fluid line coupled to the return pressure sensor and returning fluid from the pump to the reservoir. A pressure estimate is formed by establishing the second fluid line length and inner diameter as the same as the third fluid line length and inner diameter, and forming the pressure estimate by averaging the supply pressure and return pressure. The pressure controller receives a setpoint pressure as a command and data over a wireless channel, and computes a head pressure offset by turning the pump off and measuring the supply and return pressures.

Abstract: The disclosure provides novel personalized therapies, kits, transmittable forms of information and methods for use in treating patients having cancer, wherein the cancer is amenable to therapeutic treatment with an inhibitor, e.g., an inhibitor of any of the targets disclosed herein. Kits, methods of screening for candidate inhibitors, and associated methods of treatment are also provided.

Abstract: A method is described. The method includes executing solid state drive program code from system memory of a computing system to perform any/all of garbage collection, wear leveling and logical block address to physical block address translation routines for a solid state drive that is coupled to a computing system that the system memory is a component of.

Abstract: The present invention relates to compounds and methods which may be useful as treatments of diseases.

Abstract: The present disclosure provides methods of treating or reducing the symptoms of muscular dystrophy in a human patient between the age of 1 day and 18 years old, comprising administering to the human patient in need thereof a therapeutically effective amount of a vamorolone and/or a salt thereof.

Abstract: The present invention relates to compounds and methods which may be useful as treatments of neuromuscular diseases such as muscular dystrophy, and as inhibitors of NF-?B for the treatment or prevention of muscular wasting disease, including muscular dystrophy.

Abstract: The present disclosure provides a method of treating or reducing the symptoms of congenital adrenal hypoplasia in a human patient, comprising administering to the human patient in need thereof a therapeutically effective amount of vamorolone or a salt or polymorph thereof.

Abstract: The present disclosure provides methods of treating or reducing the symptoms of muscular dystrophy in a human patient between the age of 1 day and 18 years old, comprising administering to the human patient in need thereof a therapeutically effective amount of a vamorolone and/or a salt thereof.

Abstract: A surface cleaner configured to distribute a liquid to a surface to be cleaned. The surface cleaner includes a supply tank, a fluid distributor, a suction inlet aperture, a recovery tank and a tool removably connectable to the surface cleaner and configured to direct fluid from the fluid distributor into the suction inlet aperture to rinse the suction inlet aperture.

Abstract: Systems and methods are described for monitoring usage of a medicament dispenser—particularly an inhaled medicament dispenser. The usage monitoring device is configured to emit a detection signal responsive to receiving a request to locate the medicament dispenser. The detection signal alerts presence of the medicament dispenser to the user of the medicament dispenser. The usage monitoring device can be embodied as an attachment configured to be selectively coupled to one of a variety of different inhalers including, for example, a Diskus-type inhaler and a Respimat-type inhaler.

Abstract: A surface cleaner configured to distribute a liquid to a surface to be cleaned. The surface cleaner includes a supply tank, a fluid distributor, a suction inlet aperture, a recovery tank and a tool removably connectable to the surface cleaner and configured to direct fluid from the fluid distributor into the suction inlet aperture to rinse the suction inlet aperture.

Abstract: The present invention relates to compounds and methods which may be useful as treatments of neuromuscular diseases such as muscular dystrophy, and as inhibitors of NF-?B for the treatment or prevention of muscular wasting disease, including muscular dystrophy.

Abstract: A method is described. The method includes executing solid state drive program code from system memory of a computing system to perform any/all of garbage collection, wear leveling and logical block address to physical block address translation routines for a solid state drive that is coupled to a computing system that the system memory is a component of.

Abstract: The present invention relates to compounds and methods which may be useful as treatments of diseases.

Abstract: A method is described. The method includes executing solid state drive program code from system memory of a computing system to perform any/all of garbage collection, wear leveling and logical block address to physical block address translation routines for a solid state drive that is coupled to a computing system that the system memory is a component of.

Abstract: A machine implemented method includes acquiring at a processor a first image of a patent by performing a computed tomography (CT) scan of a patient and applying at the processor a generative neural network model to the first image of the patient to generate a second image of the patient. The method may further include performing, at the processor, an analysis using the first image and the second image. The first image may be a first pulmonary image and the second image may be a second pulmonary image. The first pulmonary image may show lungs at a first volume and the second pulmonary image may show the lungs at a second volume, the first volume different from the second volume. The first pulmonary image may be a scan of the lungs at expiration and the second pulmonary image may be an inspiratory image of the lungs.

Abstract: This disclosure describes the use of a phosphodiesterase-5 (PDE5) inhibitor to reduce an individual's desire to smoke and/or frequency of smoking. In some embodiments, the PDE5 inhibitor is sildenafil (e.g., Viagra).

Abstract: Described herein are method and apparatus for servicing software components of nodes of a cluster storage system. During data-access sessions with clients, client IDs and file handles for accessing files are produced and stored to clients and stored (as session data) to each node. A serviced node is taken offline, whereby network connections to clients are disconnected. Each disconnected client is configured to retain its client ID and file handles and attempt reconnections. Session data of the serviced node is made available to a partner node (by transferring session data to the partner node). After clients have reconnected to the partner node, the clients may use the retained client IDs and file handles to continue a data-access session with the partner node since the partner node has access to the session data of the serviced node and thus will recognize and accept the retained client ID and file handles.