Patents by Inventor Eric J. Schepers
Eric J. Schepers has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10435706Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: October 14, 2015Date of Patent: October 8, 2019Assignees: PIONEER HI-BRED INTERNATIONAL, INC., E I DU PONT DE NEMOURS AND COMPANYInventors: Jennifer Kara Barry, Deborah W. Clark, James J English, Azalea Ong, Eric J Schepers, Julie Qi, Janet A. Rice
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Patent number: 10294490Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: September 23, 2016Date of Patent: May 21, 2019Assignees: PIONEER HI-BRED INTERNATIONAL, INC., E I DU PONT NEMOURS AND COMPANYInventors: Daniel J Altier, Jennifer K Barry, Carol A Hendrick, Lu Liu, Phillip A Patten, Claudia D Perez-Ortega, Eric J Schepers, Weiping Xie, Nasser Yalpani, Jianzhou Zhao, Xiaohong Zhong, Genhai Zhu
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Publication number: 20170233440Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: October 14, 2015Publication date: August 17, 2017Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANYInventors: JENNIFER KARA BARRY, DEBORAH W. CLARK, JAMES J ENGLISH, AZALEA ONG, ERIC J SCHEPERS, JULIE QI, JANET A. RICE
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Publication number: 20170006867Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: September 23, 2016Publication date: January 12, 2017Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANYInventors: DANIEL J ALTIER, JENNIFER K BARRY, CAROL A HENDRICK, LU LIU, PHILLIP A PATTEN, CLAUDIA D PEREZ-ORTEGA, ERIC J SCHEPERS, WEIPING XIE, NASSAR YALPANI, JIANZHOU ZHAO, XIAOHONG ZHONG, GENHAI ZHU
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Patent number: 9475847Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: GrantFiled: March 13, 2013Date of Patent: October 25, 2016Assignees: PIONEER HI-BRED INTERNATIONAL, INC., E.I. DU PONT DE NEMOURS AND COMPANYInventors: Daniel J. Altier, Jennifer K. Barry, Carol A. Hendrick, Lu Liu, Phillip A. Patten, Claudia D. Perez-Ortega, Eric J. Schepers, Weiping Xie, Nasser Yalpani, Jianzhou Zhao, Xiaohong Zhong, Genhai Zhu
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Patent number: 8802932Abstract: Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include amino acid sequences, and variants and fragments thereof, for family members of a novel family of antipathogenic polypeptides. Polynucleotides that encode the antipathogenic polypeptides are also provided. A method for inducing pathogen resistance in a plant using the polynucleotides disclosed herein is further provided. Compositions comprising an antipathogenic polypeptide or a microorganism comprising an antipathogenic polynucleotide of the invention in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided. Plants, plant cells, seeds, and microorganisms comprising an antipathogenic polnucleotide or polypeptide of the invention are also disclosed.Type: GrantFiled: August 9, 2011Date of Patent: August 12, 2014Assignees: Pioneer Hi Bred International Inc, E I Du Pont De Nemours and CompanyInventors: Daniel J. Altier, Jacob T. Gilliam, Eric J. Schepers, Nasser Yalpani
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Publication number: 20140033361Abstract: Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.Type: ApplicationFiled: March 13, 2013Publication date: January 30, 2014Applicants: E.I Du PONT de NEMOURS and COMPANY, PIONEER HI BRED INTERNATIONAL INCInventors: Daniel J. Altier, Jennifer K. Barry, Carol A. Hendrick, Lu Liu, Phillip A. Patten, Claudia D. Perez-Ortega, Eric J. Schepers, Weiping Xie, Nasser Yalpani, Jianzhou Zhao, Xiaohong Zhong, Genhai Zhu
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Publication number: 20120054910Abstract: Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include amino acid sequences, and variants and fragments thereof, for family members of a novel family of antipathogenic polypeptides. Polynucleotides that encode the antipathogenic polypeptides are also provided. A method for inducing pathogen resistance in a plant using the polynucleotides disclosed herein is further provided. Compositions comprising an antipathogenic polypeptide or a microorganism comprising an antipathogenic polynucleotide of the invention in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided. Plants, plant cells, seeds, and microorganisms comprising an antipathogenic polnucleotide or polypeptide of the invention are also disclosed.Type: ApplicationFiled: August 9, 2011Publication date: March 1, 2012Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Daniel J. Altier, Jacob T. Gilliam, Eric J. Schepers, Nasser Yalpani
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Patent number: 7700832Abstract: Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include amino acid sequences, and variants and fragments thereof, for antipathogenic polypeptides that were isolated from fungal fermentation broths. Nucleic acids that encode the antipathogenic polypeptides are also provided. A method for inducing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant an expression cassette comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the invention. Compositions comprising an antipathogenic polypeptide or a transformed microorganism comprising a nucleic acid of the invention in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided.Type: GrantFiled: November 5, 2008Date of Patent: April 20, 2010Assignees: Pioneer Hi-Bred International, Inc., E.I. du Pont de Nemours and Company, The Regents of the University of CaliforniaInventors: Daniel J. Altier, Virginia C. Crane, Irina Ellanskaya, Natalia Ellanskaya, legal representative, Jacob T. Gilliam, Jennie Hunter-Cevera, James K. Presnail, Eric J. Schepers, Carl R. Simmons, Tamas Torok, Nasser Yalpani
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Patent number: 7598346Abstract: The invention relates to compositions including amino acid sequences isolated from fungal fermentation broths and methods for protecting a plant from a pathogen, particularly a fungal pathogen.Type: GrantFiled: May 15, 2007Date of Patent: October 6, 2009Assignees: Pioneer Hi-Bred International, Inc., E. I. du Pont de Nemours and Company, The Regents of the University of CaliforniaInventors: Daniel J. Altier, Virginia C. Crane, Irina Ellanskaya, Natalia Ellanskaya, legal representative, Jacob T. Gilliam, Jennie Hunter-Cevera, James K. Presnail, Eric J. Schepers, Carl R. Simmons, Tamas Torok, Nasser Yalpani
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Publication number: 20090089895Abstract: Compositions and methods for protecting a plant from a pathogen, particularly a fungal pathogen, are provided. Compositions include amino acid sequences, and variants and fragments thereof, for antipathogenic polypeptides that were isolated from fungal fermentation broths. Nucleic acids that encode the antipathogenic polypeptides are also provided. A method for inducing pathogen resistance in a plant using the nucleotide sequences disclosed herein is further provided. The method comprises introducing into a plant an expression cassette comprising a promoter operably linked to a nucleotide sequence that encodes an antipathogenic polypeptide of the invention. Compositions comprising an antipathogenic polypeptide or a transformed microorganism comprising a nucleic acid of the invention in combination with a carrier and methods of using these compositions to protect a plant from a pathogen are further provided.Type: ApplicationFiled: November 5, 2008Publication date: April 2, 2009Applicants: Pioneer Hi-Bred International, Inc., E.I. du PONT de NEMOURS and COMPANY, The Regents of The University of CaliforniaInventors: Daniel J. Altier, Virginia C. Crane, Irina Ellanskaya, Jacob T. Gilliam, Jennie Hunter-Cevera, James K. Presnail, Eric J. Schepers, Carl R. Simmons, Tamas Torok, Nasser Yalpani, Natalia Ellanskaya
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Patent number: 7473821Abstract: Compositions and methods for protecting a plant from an insect pest are provided. Nucleic acid molecules encoding insect protoxins or insect toxins modified to comprise at least one proteolytic activation site that is sensitive to an insect gut protease are provided. Cleavage of a modified insect protoxin at the proteolytic activation site by an insect gut protease produces an active insect toxin in the gut of the insect pest. Cleavage of a modified insect toxin of the invention at a proteolytic activation site results in the production of an active insect toxin in the insect gut that displays improved pesticidal activity relative to the insect toxin that lacks the proteolytic activation site. Methods of using the modified insect protoxin and modified insect toxin nucleic acid sequences and the polypeptides they encode to protect a plant from an insect pest are provided.Type: GrantFiled: June 7, 2006Date of Patent: January 6, 2009Assignees: Pioneer Hi-Bred International, Inc., E.I. du Pont de Nemours and CompanyInventors: Andre R. Abad, Gary C. Chun, Ronald D. Flannagan, Rafael Herrmann, Albert L. Lu, Janet A. Rice, Eric J. Schepers
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Patent number: 7462760Abstract: Compositions and methods for protecting a plant from an insect pest are provided. The invention provides mutagenized nucleic acids that have been engineered to encode pesticidal polypeptides having increased resistance to proteolytic degradation by a plant protease. In particular, nucleic acid sequences encoding pesticidal polypeptides modified to comprise a proteolytic protection site that confers resistance to degradation or proteolytic inactivation by a plant protease are provided. Particular embodiments of the invention provide expression cassettes and transformed plants, plant cells, and seeds. These compositions find use in methods for protecting a plant from a pest.Type: GrantFiled: December 24, 2003Date of Patent: December 9, 2008Assignees: Pioneer Hi-Bred International, Inc., E.I. duPont de Nemours and CompanyInventors: André Abad, Hua Dong, Rafael Herrmann, Albert Lu, Billy F. McCutchen, Janet A. Rice, Eric J. Schepers, James F. Wong
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Publication number: 20040210963Abstract: Compositions and methods for protecting a plant from an insect pest are provided. The invention provides mutagenized nucleic acids that have been engineered to encode pesticidal polypeptides having increased resistance to proteolytic degradation by a plant protease. In particular, nucleic acid sequences encoding pesticidal polypeptides modified to comprise a proteolytic protection site that confers resistance to degradation or proteolytic inactivation by a plant protease are provided. Particular embodiments of the invention provide pesticidal polypeptide compositions and formulations, expression cassettes, and transformed plants, plant cells, and seeds. These compositions find use in methods for controlling pests, especially plant pests. Novel plant proteases, sequences encoding these proteases, and methods for their use are also provided.Type: ApplicationFiled: December 24, 2003Publication date: October 21, 2004Applicants: Pioneer Hi-Bred International, Inc., E.I. du PONT de NEMOURS and COMPANYInventors: Andre Abad, Hua Dong, Rafael Herrmann, Albert Lu, Billy F. McCutchen, Janet A. Rice, Eric J. Schepers, James F. Wong