Patents by Inventor Eric J. Seibel

Eric J. Seibel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11330170
    Abstract: Methods and systems for acquiring and/or projecting images from and/or to a target area are provided. Such a method or system can include an optical fiber assembly which may be driven to scan the target area in a scan pattern. The optical fiber assembly may provide multiple effective light sources (e.g., via a plurality of optical fibers) that are axially staggered with respect to an optical system located between the optical fiber and the target area. The optical system may be operable to focus and/or redirect the light from the multiple light sources onto separate focal planes. A composite image may be generated based on light reflected from and/or projected onto the separate focal planes. The composite image may have an extended depth of focus or field spanning over a distance between the separate focal planes while maintaining or improving image resolution.
    Type: Grant
    Filed: December 10, 2019
    Date of Patent: May 10, 2022
    Assignee: UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION
    Inventors: Eric J. Seibel, Brian T. Schowengerdt
  • Publication number: 20220061825
    Abstract: A monitoring system includes a light source, a light detector, a processor, and a non-transitory computer readable medium storing instructions that, when executed by the processor, cause the monitoring system to perform functions. The functions include illuminating, via the light source, a biological sample that is within a container while a fixation process is performed on the biological sample. The functions also include determining, via the light detector, that an optical transmittance of the biological sample satisfies a condition. The functions also include ceasing the fixation process in response to determining that the optical transmittance of the biological sample satisfies the condition.
    Type: Application
    Filed: August 12, 2021
    Publication date: March 3, 2022
    Inventors: Eric J. Seibel, Saniel D. Lim, Mark E. Fauver
  • Patent number: 11252385
    Abstract: Image projection devices, high-speed fiber scanned displays and related methods for projecting an image onto a surface and interfacing with the projected image are provided. A method for projecting one or more images and obtaining feedback with an optical input-output assembly is provided. The input-output assembly comprising a light-scanning optical fiber and a sensor. The method includes generating a sequence of light in response to one or more image representations and a scan pattern of the optical fiber, articulating the optical fiber in the scan pattern, projecting the sequence of light from the articulated optical fiber, and generating a feedback signal with the sensor in response to reflections of the sequence of light.
    Type: Grant
    Filed: January 4, 2018
    Date of Patent: February 15, 2022
    Assignee: University of Washington
    Inventors: Charles D. Melville, Richard S. Johnston, Cameron M. Lee, Eric J. Seibel, Brian T. Schowengerdt
  • Publication number: 20220015614
    Abstract: Apparatuses and methods for imaging objects in cardiovascular system are described. In one embodiment, an apparatus includes a catheter configured to traverse a blood vessel. The catheter includes: a flushing fluid inlet configured to inject a flushing fluid into the blood vessel; a flushing fluid outlet configured to evacuate the flushing fluid from the blood vessel; and an imaging module configured to image an object in the blood vessel. A first volumetric flow of the flushing fluid into the blood vessel and a second volumetric flow of the flushing fluid out of the blood vessel are synchronized to maintain a pressure in the blood vessel below a predetermined threshold.
    Type: Application
    Filed: December 11, 2019
    Publication date: January 20, 2022
    Inventors: Syed Faisal, Alberto Aliseda, Eric J. Seibel
  • Publication number: 20220015629
    Abstract: A retina image template matching method is based on the registration and comparison between the images captured with portable low-cost fundus cameras (e.g., a consumer grade camera typically incorporated into a smartphone or tablet computer) and a baseline image. The method solves the challenges posed by registering small and low-quality retinal template images captured with such cameras. Our method combines dimension reduction methods with a mutual information (MI) based image registration technique. In particular, principle components analysis (PCA) and optionally block PCA are used as a dimension reduction method to localize the template image coarsely to the baseline image, then the resulting displacement parameters are used to initialize the MI metric optimization for registration of the template image with the closest region of the baseline image.
    Type: Application
    Filed: November 20, 2019
    Publication date: January 20, 2022
    Applicant: MAGIC LEAP, INC.
    Inventors: Eric J. SEIBEL, Chen GONG, Steven L. BRUNTON, Nils Benjamin ERICHSON, Laura TRUTOIU, Brian T. SCHOWENGERDT
  • Publication number: 20210397254
    Abstract: Techniques for tracking eye movement in an augmented reality system identify a plurality of base images of an object or a portion thereof. A search image may be generated based at least in part upon at least some of the plurality of base images. A deep learning result may be generated at least by performing a deep learning process on a base image using a neural network in a deep learning mode. A captured image may be localized at least by performing an image registration process on the captured image and the search image using a Kalman filter model and the deep learning result.
    Type: Application
    Filed: June 11, 2021
    Publication date: December 23, 2021
    Applicants: UNIVERSITY OF WASHINGTON, MAGIC LEAP, INC.
    Inventors: Eric J. SEIBEL, Steven L. BRUNTON, Chen GONG, Brian T. SCHOWENGERDT
  • Publication number: 20210263051
    Abstract: Systems and methods for accurate optical pH sensing of biofilms are disclosed. In one embodiment, a method of measuring an extracellular pH level using multiple wavelengths emitted by a fluorescent substance includes: exciting the fluorescent substance at an excitation wavelength; measuring a first fluorescence intensity at a first wavelength of a fluorescence emission; and measuring a second fluorescence intensity at a second wavelength of the fluorescence emission. The second wavelength is different from the first wavelength. The method also includes determining the extracellular pH level based on the first fluorescence intensity at the first wavelength and the second fluorescence intensity at the second wavelength.
    Type: Application
    Filed: July 19, 2019
    Publication date: August 26, 2021
    Applicant: University of Washington
    Inventors: Eric J. Seibel, Leonard Y. Nelson, Manuja Sharma, Jasmine Graham
  • Patent number: 10888230
    Abstract: Methods and systems for detecting early stage dental caries and decays are provided. In particular, in an embodiment, laser-induced autofluorescence (AF) from multiple excitation wavelengths is obtained and analyzed. Endogenous fluorophores residing in the enamel naturally fluoresce when illuminated by wavelengths ranging from ultraviolet into the visible spectrum. The relative intensities of the AF emission changes between different excitation wavelengths when the enamel changes from healthy to demineralized. By taking a ratio of AF emission spectra integrals between different excitation wavelengths, a standard is created wherein changes in AF ratios within a tooth are quantified and serve as indicators of early stage enamel demineralization. The techniques described herein may be used in conjunction with a scanning fiber endoscope (SFE) to provide a reliable, safe and low-cost means for identifying dental caries or decays.
    Type: Grant
    Filed: January 11, 2018
    Date of Patent: January 12, 2021
    Assignee: University of Washington through its Center for Commercialization
    Inventors: Eric J. Seibel, Leonard Y. Nelson
  • Patent number: 10852291
    Abstract: An example fluidic device may include a plurality of channels including one or more curved channels having a channel input and a channel output. Each of the one or more curved channels may have a substantially circular cross-section. The fluidic device may also include an input interface between the channel input of the one or more curved channels and an exterior of the fluidic device. The input interface may be configured to receive a biological tissue sample. The fluidic device may also include an output interface between the channel output of the one or more curved channels and the exterior of the fluidic device.
    Type: Grant
    Filed: February 3, 2016
    Date of Patent: December 1, 2020
    Assignee: University of Washington
    Inventors: Eric J. Seibel, Ronnie Das, Christopher W. Burfeind, Thu-mai Nguyen
  • Publication number: 20200346205
    Abstract: An example fluidic device includes an elastic tube, a first actuator coupled to an outer surface of the elastic tube between a first end and a second end of the elastic tube, and a second actuator coupled to the outer surface of the elastic tube between the first actuator and the second end of the elastic tube. The first actuator and the second actuator are configured to move apart from one another to transition a portion of the elastic tube positioned between the first actuator and the second actuator from a first condition to a second condition. A diameter of the elastic tube is greater in the first condition than in the second condition. The fluidic device also includes one or more rotatable components coupled to the first actuator and the second actuator which are configured to rotate the portion of the elastic tube positioned between the first actuator and the second actuator.
    Type: Application
    Filed: November 6, 2018
    Publication date: November 5, 2020
    Inventors: Mark E. Fauver, Eric J. Seibel
  • Publication number: 20200112674
    Abstract: Methods and systems for acquiring and/or projecting images from and/or to a target area are provided. Such a method or system can include an optical fiber assembly which may be driven to scan the target area in a scan pattern. The optical fiber assembly may provide multiple effective light sources (e.g., via a plurality of optical fibers) that are axially staggered with respect to an optical system located between the optical fiber and the target area. The optical system may be operable to focus and/or redirect the light from the multiple light sources onto separate focal planes. A composite image may be generated based on light reflected from and/or projected onto the separate focal planes. The composite image may have an extended depth of focus or field spanning over a distance between the separate focal planes while maintaining or improving image resolution.
    Type: Application
    Filed: December 10, 2019
    Publication date: April 9, 2020
    Inventors: Eric J. Seibel, Brian T. Schowengerdt
  • Patent number: 10557778
    Abstract: An imaging and diagnostic system and method for focal scanning of a specimen using optical projection tomographic microscopy and computer generation of three-dimensional images is disclosed. One embodiment includes a light source and an imaging system having an adjustable focal position, which acquires a plurality of digital 2D projection images of biological tissue placed within a specimen tube that translates and rotates past an optical lens in a helical pattern. A computer captures the images and generates a 3D composite image. Also disclosed is a system and method for preparing a specimen for optical microscopy. One embodiment includes fixing, staining, and/or optically clearing biological tissue within a microfluidic specimen chamber prior to placement in a specimen tube.
    Type: Grant
    Filed: August 7, 2014
    Date of Patent: February 11, 2020
    Inventors: Eric J. Seibel, Qin Miao, Ryan Lee Coe, Per G. Reinhall
  • Patent number: 10542209
    Abstract: Methods and systems for acquiring and/or projecting images from and/or to a target area are provided. Such a method or system can includes an optical fiber assembly which may be driven to scan the target area in a scan pattern. The optical fiber assembly may provide multiple effective light sources (e.g., via a plurality of optical fibers) that are axially staggered with respect to an optical system located between the optical fiber and the target area. The optical system may be operable to focus and/or redirect the light from the multiple light sources onto separate focal planes. A composite image may be generated based on light reflected from and/or projected onto the separate focal planes. The composite image may have an extended depth of focus or field spanning over a distance between the separate focal planes while maintaining or improving image resolution.
    Type: Grant
    Filed: July 10, 2017
    Date of Patent: January 21, 2020
    Assignee: University of Washington through its Center for Commercialization
    Inventors: Eric J. Seibel, Brian T. Schowengerdt
  • Publication number: 20190328234
    Abstract: A system for the optical measurement of pH includes a light emitter to emit an excitation light, and a detector coupled to receive florescence light produced by a compound in a mouth of a patient in response to the excitation light. A controller is coupled to the detector, and the controller includes logic that when executed by the controller, causes the system to perform operations. The operations may include emitting the excitation light from the light emitter; measuring an intensity of the florescence light emitted from a surface of individual teeth in a plurality of teeth in the mouth; and determining, based on the intensity of the florescence light, one or more locations on the individual teeth likely to develop demineralization.
    Type: Application
    Filed: October 27, 2017
    Publication date: October 31, 2019
    Inventors: Eric J. Seibel, Yuanzheng Gong, Zheng Xu, Jeffrey S. McLean, Yaxuan Zhou
  • Patent number: 10349818
    Abstract: Improved systems, methods, and devices relating to optical fiber scanners are provided. In one aspect, a scanning apparatus includes an optical fiber and a piezoelectric actuator coupled to the optical fiber to deflect a distal end of the optical fiber in a scanning pattern. The apparatus can include drive circuitry coupled to the piezoelectric actuator, sense circuitry electrically coupled to the piezoelectric actuator and the drive circuitry to determine displacement of the piezoelectric actuator, and a processor coupled to the drive circuitry and the sense circuitry to drive the piezoelectric actuator in response to the displacement.
    Type: Grant
    Filed: December 7, 2017
    Date of Patent: July 16, 2019
    Assignee: University of Washington through its Center for Commercialization
    Inventors: Ivan L. Yeoh, Per G. Reinhall, Eric J. Seibel, Matthew J. Kundrat
  • Publication number: 20180353640
    Abstract: A photosensitive medical tape includes a backing layer that is at least partially transparent to a first spectrum of electromagnetic radiation. The photosensitive medical tape also includes a coupling layer disposed on a first side of the backing layer to provide adhesion of the photosensitive medical tape to the human skin. The photosensitive medical tape is disposed to absorb a second spectrum of electromagnetic radiation to decrease a strength of the adhesion provided by the coupling layer. The photosensitive medical tape is also flexible.
    Type: Application
    Filed: November 21, 2016
    Publication date: December 13, 2018
    Inventors: Eric J. Seibel, Leonard Nelson
  • Patent number: 10130243
    Abstract: The image-based feedback endoscopy system includes a steering apparatus having a base platform, a pair of servomotors, a rigid tube, and a biasing member. A flexion member has a tether member and a ball screw, the tether member being in communication with the biasing member. The image-based feedback endoscopy system further includes an endoscope having a tip. The endoscope is positioned through the concentric spring such that the tip extends from the biasing member. The endoscope is in communication with the flexion member such that the endoscope is selectively movable by the pair of servomotors selectively controlling the flexion member. The endoscope includes a piezo actuator, a scanning fiber, a lens assembly, and collection fibers. The image-based feedback endoscopy system also includes an image based feedback algorithm, which selectively controls the operation of the pair of servo motors.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: November 20, 2018
    Assignee: Qatar University Al Tarfa
    Inventors: Woon Jong Yoon, Eric J. Seibel, Matthew R. Burkhardt, Timothy D. Soper
  • Patent number: 10080484
    Abstract: Improved methods, systems and apparatus relating to wide field fluorescence and reflectance imaging are provided, including improved methods, systems and apparatus relating to removal of background signals such as autofluorescence and/or fluorophore emission cross-talk; distance compensation of fluorescent signals; and co-registration of multiple signals emitted from three dimensional tissues.
    Type: Grant
    Filed: January 30, 2015
    Date of Patent: September 25, 2018
    Assignee: University of Washington
    Inventors: Chenying Yang, Eric J. Seibel, Leonard Y. Nelson, Timothy D. Soper
  • Publication number: 20180249913
    Abstract: Methods and systems for detecting early stage dental caries and decays are provided. In particular, in an embodiment, laser-induced autofluorescence (AF) from multiple excitation wavelengths is obtained and analyzed. Endogenous fluorophores residing in the enamel naturally fluoresce when illuminated by wavelengths ranging from ultraviolet into the visible spectrum. The relative intensities of the AF emission changes between different excitation wavelengths when the enamel changes from healthy to demineralized. By taking a ratio of AF emission spectra integrals between different excitation wavelengths, a standard is created wherein changes in AF ratios within a tooth are quantified and serve as indicators of early stage enamel demineralization. The techniques described herein may be used in conjunction with a scanning fiber endoscope (SFE) to provide a reliable, safe and low-cost means for identifying dental caries or decays.
    Type: Application
    Filed: January 11, 2018
    Publication date: September 6, 2018
    Applicant: University of Washington through its Center for Commercialization
    Inventors: Eric J. Seibel, Leonard Y. Nelson
  • Publication number: 20180199015
    Abstract: Image projection devices, high-speed fiber scanned displays and related methods for projecting an image onto a surface and interfacing with the projected image are provided. A method for projecting one or more images and obtaining feedback with an optical input-output assembly is provided. The input-output assembly comprising a light-scanning optical fiber and a sensor. The method includes generating a sequence of light in response to one or more image representations and a scan pattern of the optical fiber, articulating the optical fiber in the scan pattern, projecting the sequence of light from the articulated optical fiber, and generating a feedback signal with the sensor in response to reflections of the sequence of light.
    Type: Application
    Filed: January 4, 2018
    Publication date: July 12, 2018
    Inventors: Charles D. MELVILLE, Richard S. Johnston, Cameron M. Lee, Eric J. Seibel, Brian T. Schowengerdt