Patents by Inventor Eric J. Steen

Eric J. Steen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • RECOMBINANT HOST CELLS FOR THE PRODUCTION OF MALONATE
    Publication number: 20240191216
    Abstract: Systems and methods for the production of malonate in recombinant host cells.
    Type: Application
    Filed: March 20, 2023
    Publication date: June 13, 2024
    Applicant: LYGOS, INC.
    Inventors: Jeffrey A. Dietrich, Jeffrey L. Fortman, Eric J. Steen
  • RECOMBINANT HOST CELLS FOR THE PRODUCTION OF MALONATE
    Publication number: 20220119783
    Abstract: Systems and methods for the production of malonate in recombinant host cells.
    Type: Application
    Filed: December 29, 2021
    Publication date: April 21, 2022
    Inventors: Jeffrey A. Dietrich, Jeffrey L. Fortman, Eric J. Steen
  • Recombinant host cells for the production of malonate
    Patent number: 11248215
    Abstract: Systems and methods for the production of malonate in recombinant host cells.
    Type: Grant
    Filed: October 7, 2019
    Date of Patent: February 15, 2022
    Assignee: Lygos, Inc.
    Inventors: Jeffrey A. Dietrich, Jeffrey L. Fortman, Eric J. Steen
  • RECOMBINANT HOST CELLS FOR THE PRODUCTION OF MALONATE
    Publication number: 20200071733
    Abstract: Systems and methods for the production of malonate in recombinant host cells.
    Type: Application
    Filed: October 7, 2019
    Publication date: March 5, 2020
    Inventors: Jeffrey A. Dietrich, Jeffrey L. Fortman, Eric J. Steen
  • Recombinant host cells for the production of malonate
    Patent number: 10472653
    Abstract: Systems and methods for the production of malonate in recombinant host cells.
    Type: Grant
    Filed: June 19, 2017
    Date of Patent: November 12, 2019
    Assignee: Lygos, Inc.
    Inventors: Jeffrey A. Dietrich, Jeffrey L. Fortman, Eric J. Steen
  • Host cells and methods for producing diacid compounds
    Patent number: 9951345
    Abstract: The present invention provides for a method of producing one or more fatty acid derived dicarboxylic acids in a genetically modified host cell which does not naturally produce the one or more derived fatty acid derived dicarboxylic acids. The invention provides for the biosynthesis of dicarboxylic acid ranging in length from C3 to C26. The host cell can be further modified to increase fatty acid production or export of the desired fatty acid derived compound, and/or decrease fatty acid storage or metabolism.
    Type: Grant
    Filed: May 22, 2013
    Date of Patent: April 24, 2018
    Assignee: The Regents of the University of California
    Inventors: Eric J. Steen, Jeffrey L. Fortman, Jeffrey A. Dietrich, Jay D. Keasling
  • Producing alpha-olefins using polyketide synthases
    Patent number: 9856461
    Abstract: The present invention provides for a polyketide synthase (PKS) capable of synthesizing an ?-olefin, such as 1-hexene or butadiene. The present invention also provides for a host cell comprising the PKS and when cultured produces the ?-olefin.
    Type: Grant
    Filed: September 14, 2015
    Date of Patent: January 2, 2018
    Assignee: The Regents of the University of California
    Inventors: Jeffrey L. Fortman, Leonard Katz, Eric J. Steen, Jay D Keasling
  • RECOMBINANT HOST CELLS FOR THE PRODUCTION OF MALONATE
    Publication number: 20170362614
    Abstract: Systems and methods for the production of malonate in recombinant host cells.
    Type: Application
    Filed: June 19, 2017
    Publication date: December 21, 2017
    Applicant: Lygos, Inc.
    Inventors: Jeffrey A. Dietrich, Jeffrey L. Fortman, Eric J. Steen
  • Recombinant host cells for the production of malonate
    Patent number: 9816114
    Abstract: Systems and methods for the production of malonate in recombinant host cells.
    Type: Grant
    Filed: March 6, 2013
    Date of Patent: November 14, 2017
    Assignee: Lygos, Inc.
    Inventors: Jeffrey A. Dietrich, Jeffrey L. Fortman, Eric J. Steen
  • RECOMBINANT HOST CELLS FOR THE PRODUCTION OF MALONATE
    Publication number: 20160177345
    Abstract: Systems and methods for the production of malonate in recombinant host cells.
    Type: Application
    Filed: March 6, 2013
    Publication date: June 23, 2016
    Inventors: Jeffrey A. Dietrich, Jeffrey L. Fortman, Eric J. Steen
  • PRODUCING ALPHA-OLEFINS USING POLYKETIDE SYNTHASES
    Publication number: 20160068827
    Abstract: The present invention provides for a polyketide synthase (PKS) capable of synthesizing an ?-olefin, such as 1-hexene or butadiene. The present invention also provides for a host cell comprising the PKS and when cultured produces the ?-olefin.
    Type: Application
    Filed: September 14, 2015
    Publication date: March 10, 2016
    Inventors: Jeffrey L. Fortman, Leonard Katz, Eric J. Steen, Jay D. Keasling
  • PRODUCT OF FATTY ACID ESTERS FROM BIOMASS POLYMERS
    Publication number: 20140038248
    Abstract: The invention provides consolidated bioprocessing methods and host cells. The host cells are capable of directly converting biomass polymers or sunlight into biodiesel equivalents and other fatty acid derivatives. In particular, the invention provides a method for producing biodiesel equivalents and other fatty acid derivatives from a biomass polymer including providing a genetically engineered host cell, culturing the host cell in a medium containing a carbon source such that recombinant nucleic acids in the cell are expressed, and extracting biodiesel equivalents and other fatty acid derivatives from the culture.
    Type: Application
    Filed: August 6, 2013
    Publication date: February 6, 2014
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jay D. KEASLING, Yisheng (Connie) KANG, Eric J. STEEN, Gregory BOKINSKY
  • Host Cells and Methods for Producing Diacid Compounds
    Publication number: 20130267012
    Abstract: The present invention provides for a method of producing one or more fatty acid derived dicarboxylic acids in a genetically modified host cell which does not naturally produce the one or more derived fatty acid derived dicarboxylic acids. The invention provides for the biosynthesis of dicarboxylic acid ranging in length from C3 to C26. The host cell can be further modified to increase fatty acid production or export of the desired fatty acid derived compound, and/or decrease fatty acid storage or metabolism.
    Type: Application
    Filed: May 22, 2013
    Publication date: October 10, 2013
    Inventors: Eric J. Steen, Jeffrey L. Fortman, Jeffrey A. Dietrich, Jay D. Keasling
  • PRODUCING ALPHA-OLEFINS USING POLYKETIDE SYNTHASES
    Publication number: 20130267696
    Abstract: The present invention provides for a polyketide synthase (PKS) capable of synthesizing an ?-olefin, such as 1-hexene or butadiene. The present invention also provides for a host cell comprising the PKS and when cultured produces the ?-olefin.
    Type: Application
    Filed: September 28, 2011
    Publication date: October 10, 2013
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Jeffrey L. Fortman, Leonard Katz, Eric J. Steen, Jay D. Keasling
  • Host Cells and Methods for Producing Fatty Acid
    Publication number: 20130059295
    Abstract: The present invention provides for a genetically modified host cell capable of producing fatty acid comprising an increased expression of FadR, or a functional variant thereof. The host cell under environmental conditions wherein fatty acid is produced expresses an increased amount of FadR when compared to an unmodified host cell. The present invention also provides for a method of producing a fatty acid or FAAE in the host cell. The present invention provides for a genetically modified host cell comprising a fatty acid biosensor and one or more fatty acid-responsive promoter operably linked to one or more genes of interest that is heterologous to the fatty acid-responsive promoter.
    Type: Application
    Filed: July 13, 2012
    Publication date: March 7, 2013
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Fuzhong Zhang, Eric J. Steen, Jay D. Keasling
  • PRODUCT OF FATTY ACID ESTERS FROM BIOMASS POLYMERS
    Publication number: 20120115195
    Abstract: The invention provides consolidated bioprocessing methods and host cells. The host cells are capable of directly converting biomass polymers or sunlight into biodiesel equivalents and other fatty acid derivatives. In particular, the invention provides a method for producing biodiesel equivalents and other fatty acid derivatives from a biomass polymer including providing a genetically engineered host cell, culturing the host cell in a medium containing a carbon source such that recombinant nucleic acids in the cell are expressed, and extracting biodiesel equivalents and other fatty acid derivatives from the culture.
    Type: Application
    Filed: April 30, 2010
    Publication date: May 10, 2012
    Applicant: The Regents of the University of California
    Inventors: Jay D. Keasling, Yisheng (Connie) Kang, Eric J. Steen, Gregory Bokinsky
  • Host Cells and Methods for Producing Fatty Acid Derived Compounds
    Publication number: 20100170148
    Abstract: The present invention provides for a method of producing one or more fatty acid derived compounds in a genetically modified host cell which does not naturally produce the one or more derived fatty acid derived compounds. The invention provides for the biosynthesis of fatty acid derived compounds such as C18 aldehydes, C18 alcohols, C18 alkanes, and C17 alkanes from C18-CoA which in turn is synthesized from butyryl-CoA. The host cell can be further modified to increase fatty acid production or export of the desired fatty acid derived compound, and/or decrease fatty acid storage or metabolism.
    Type: Application
    Filed: December 21, 2009
    Publication date: July 8, 2010
    Applicant: The Regents of the University of California
    Inventors: Eric J. Steen, Jay D. Keasling