Patents by Inventor Eric J. Suda

Eric J. Suda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR PURIFYING ANTIBODIES
    Publication number: 20200277330
    Abstract: A method for purifying a protein comprising an antibody, antibody fragment, or immunoglobulin single variable domain, from a solution containing at least one contaminant by superantigen chromatography comprising: a) adsorbing the protein to the superantigen immobilized on a solid support; b) removing the at least one contaminant by contacting the immobilized superantigen containing the adsorbed protein with a first wash buffer comprising an aliphatic carboxylate; and c) eluting the protein from the superantigen immobilized on the solid support.
    Type: Application
    Filed: May 13, 2020
    Publication date: September 3, 2020
    Inventors: Kent E. GOKLEN, Eric J. Suda, Antonio Raul Ubiera
  • Methods for purifying antibodies
    Patent number: 10676503
    Abstract: A method for purifying a protein comprising an antibody, antibody fragment, or immunoglobulin single variable domain, from a solution containing at least one contaminant by superantigen chromatography comprising: a) adsorbing the protein to the superantigen immobilized on a solid support; b) removing the at least one contaminant by contacting the immobilized superantigen containing the adsorbed protein with a first wash buffer comprising an aliphatic carboxylate; and c) eluting the protein from the superantigen immobilized on the solid support.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: June 9, 2020
    Assignee: GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED
    Inventors: Kent E. Goklen, Eric J. Suda, Antonio Raul Ubiera
  • Buffer system for protein purification
    Patent number: 9868761
    Abstract: A method for purifying a protein using a simplified, sodium chloride-free buffer system that consists of two components (acid and base pairs) for appropriate solution pH control; and a third component for ionic strength control, where the third component is the sodium salt conjugate base.
    Type: Grant
    Filed: March 6, 2017
    Date of Patent: January 16, 2018
    Assignee: GlaxoSmithKline LLC
    Inventors: Kent E. Goklen, Eric J. Suda, Antonio Raul Ubiera
  • BUFFER SYSTEM FOR PROTEIN PURIFICATION
    Publication number: 20170174721
    Abstract: A method for purifying a protein using a simplified, sodium chloride-free buffer system that consists of two components (acid and base pairs) for appropriate solution pH control; and a third component for ionic strength control, where the third component is the sodium salt conjugate base.
    Type: Application
    Filed: March 6, 2017
    Publication date: June 22, 2017
    Inventors: Kent E. GOKLEN, Eric J. SUDA, Antonio Raul UBIERA
  • Buffer system for protein purification
    Patent number: 9624261
    Abstract: The invention is directed to a method for producing a polypeptide composition comprising: combining a polypeptide with a volatile additive to form a liquid mixture and lyophilizing the liquid mixture to obtain a lyophilized polypeptide composition.
    Type: Grant
    Filed: March 29, 2012
    Date of Patent: April 18, 2017
    Assignee: GlaxoSmithKline LLC
    Inventors: Kent E. Goklen, Eric J. Suda, Antonio Raul Ubiera
  • METHODS FOR PURIFYING ANTIBODIES
    Publication number: 20160024146
    Abstract: A method for purifying a protein comprising an antibody, antibody fragment, or immunoglobulin single variable domain, from a solution containing at least one contaminant by superantigen chromatography comprising: a) adsorbing the protein to the superantigen immobilized on a solid support; b) removing the at least one contaminant by contacting the immobilized superantigen containing the adsorbed protein with a first wash buffer comprising an aliphatic carboxylate; and c) eluting the protein from the superantigen immobilized on the solid support.
    Type: Application
    Filed: March 13, 2014
    Publication date: January 28, 2016
    Inventors: Kent E. GOKLEN, Eric J. SUDA, Antoni Raul UBIERA
  • BUFFER SYSTEM FOR PROTEIN PURIFICATION
    Publication number: 20140018525
    Abstract: The invention is directed to a method for producing a polypeptide composition comprising: combining a polypeptide with a volatile additive to form a liquid mixture and lyophilizing the liquid mixture to obtain a lyophilized polypeptide composition.
    Type: Application
    Filed: March 29, 2012
    Publication date: January 16, 2014
    Applicant: GLAXOSMITHKLINE LLC
    Inventors: Kent E. Goklen, Eric J. Suda, Antonio Raul Ubiera