Patents by Inventor Eric J. Wallenstein

Eric J. Wallenstein has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Media conditioning for improving gene delivery efficiency to differentiating embryonic stem cells
    Patent number: 8993328
    Abstract: The present invention provides systems and methods for improving the efficiency of a transient gene delivery system to differentiating embryonic stem (ES) cells by serum starving the targeted cells for one to three days prior to transfection. Such a serum starvation surprisingly resulted in increased expression of a constitutively-controlled plasmid from 50.4% to 83.2% of the population and increased expression of a promoter/enhancer controlled plasmid from ˜1.4% to ˜3.7% of the population.
    Type: Grant
    Filed: September 22, 2009
    Date of Patent: March 31, 2015
    Assignee: Rutgers, The State University of New Jersey
    Inventors: Martin L. Yarmush, Eric J. Wallenstein, Rene S. Schloss
  • MEDIA CONDITIONING FOR IMPROVING GENE DELIVERY EFFICIENCY TO DIFFERENTIATING EMBRYONIC STEM CELLS
    Publication number: 20100184226
    Abstract: The present invention provides systems and methods for improving the efficiency of a transient gene delivery system to differentiating embryonic stem (ES) cells by serum starving the targeted cells for one to three days prior to transfection. Such a serum starvation surprisingly resulted in increased expression of a constitutively-controlled plasmid from 50.4% to 83.2% of the population and increased expression of a promoter/enhancer controlled plasmid from ˜1.4% to ˜3.7% of the population.
    Type: Application
    Filed: September 22, 2009
    Publication date: July 22, 2010
    Applicant: Rutgers, the State University
    Inventors: Martin L. Yarmush, Eric J. Wallenstein, Rene S. Schloss