Abstract: The present invention provides a method and apparatus for deterring pets or other animals from biting or chewing into medication containers. In some embodiments, the invention consists of two or more conductive metal sheets or strips in layers around the side of the container, which are wired to complete a circuit when pressed by the force of an animal's bite or touched by an animal's tongue. In some embodiments, the sheets or strips are spaced or held apart so that a normal human grip would not have sufficient force to complete the circuit. In some embodiments, the device slides onto the medication container with a friction fit, and is removable for use on future containers. In some embodiments, the circuit includes a battery-powered alarm to deter the animal. In other embodiments, the circuit delivers a mild electrical shock to the animal's mouth or tongue through the metal strips or sheets.

Abstract: A method for registering a catheter navigation system to a three-dimensional image generally includes obtaining a three-dimensional image including position information for a plurality of surface points on a part of a patient's body, using a catheter navigation system to place a tool at a location on the surface of the patient's body, measuring position information for the surface location, identifying a corresponding location on the image, associating position information for the surface location and the location identified on the image as a fiducial pair, and using at least one fiducial pair to generate a mapping function. The mapping function transforms points within the coordinate system of the catheter navigation to the coordinate system of the three-dimensional image such that, for each fiducial pair, the mapping error is about zero. Suitable warping algorithms include thin plate splines, mean value coordinates, and radial basis function networks.

Abstract: An embodiment of a method for solving the inverse problem of electrophysiology and determining a voltage distribution on a surface of a tissue may comprise receiving a plurality of voltages collected by a plurality of electrodes adjacent to the surface, discretizing the problem using a Finite Element Method (FEM) or a Boundary Element Method (BEM), introducing one or more regularization terms to an error minimization formulation, and solving, by a processor, the voltage distribution according to the plurality of voltages and according to the regularization terms. The regularization terms may comprise one or more of a Laplacian smoothness operator, a Tikhonov regularization matrix, a confidence matrix, and a linear operator that interpolates the plurality of electrode voltages to the tissue voltage distribution.

Abstract: The present invention provides a method and apparatus for deterring pets or other animals from biting or chewing into medication containers. In some embodiments, the invention consists of two or more conductive metal sheets or strips in layers around the side of the container, which are wired to complete a circuit when pressed by the force of an animal's bite or touched by an animal's tongue. In some embodiments, the sheets or strips are spaced or held apart so that a normal human grip would not have sufficient force to complete the circuit. In some embodiments, the device slides onto the medication container with a friction fit, and is removable for use on future containers. In some embodiments, the circuit includes a battery-powered alarm to deter the animal. In other embodiments, the circuit delivers a mild electrical shock to the animal's mouth or tongue through the metal strips or sheets.

Abstract: An electrophysiology catheter is provided. In one embodiment, the catheter includes an elongate, deformable shaft having a proximal end and a distal end and a basket electrode assembly coupled to the distal end of the shaft. The basket electrode assembly has a proximal end and a distal end and is configured to assume a compressed state and an expanded state. The electrode assembly further includes one or more tubular splines having a plurality of electrodes disposed thereon and a plurality of conductors. Each of the plurality of conductors extends through the tubular spline from a corresponding one of the plurality of electrodes to the proximal end of the basket electrode assembly. The tubular splines are configured to assume a non-planar (e.g., a twisted or helical) shape in the expanded state.

Abstract: An embodiment of a method for solving the inverse problem of electrophysiology and determining a voltage distribution on a surface of a tissue may comprise receiving a plurality of voltages collected by a plurality of electrodes adjacent to the surface, discretizing the problem using a Finite Element Method (FEM) or a Boundary Element Method (BEM), introducing one or more regularization terms to an error minimization formulation, and solving, by a processor, the voltage distribution according to the plurality of voltages and according to the regularization terms. The regularization terms may comprise one or more of a Laplacian smoothness operator, a Tikhonov regularization matrix, a confidence matrix, and a linear operator that interpolates the plurality of electrode voltages to the tissue voltage distribution.

Abstract: The instant invention relates to an electrophysiology apparatus and method used to measure electrical activity occurring in a portion of tissue of a patient and to visualize the electrical activity and/or information related to the electrical activity. In particular, the instant invention relates to three-dimensional mapping of the electrical activity and/or the information related to the electrical activity.

Abstract: A method of repairing a three dimensional surface mesh model to be watertight and manifold generally includes identifying a plurality of hole edges in the surface mesh model, selecting one of the hole edges, creating a cycle of hole edges that defines a hole in the surface mesh model, converting the cycle of hole edges into two or more cycles of exactly three edges each, and adding a triangular facet to the surface mesh model for each of the cycles of exactly three edges. The process may be repeated until the model is substantially watertight. Non-manifold vertices may be repaired by selecting a vertex of the model, identifying a number of independent cycles of triangular facets sharing the selected vertex, and redefining the selected vertex for at least all but one of the number of independent cycles. This process may be repeated until the model is manifold.

Abstract: A body-surface mapping system is disclosed that uses a plurality of electrodes to map at least a portion of a human torso without having to adjust the positions of the electrodes. The body-surface mapping system energizes groupings or regions of electrodes, then compares and adjusts the current driven through each grouping or region of electrodes to produce near-uniform fields. The electrodes of the body-surface mapping system may be interconnected by wires capable of sensing interelectrode distances, such that the system can reconstruct a detailed model of a patient's torso surface. The body-surface mapping system may also use a catheter in addition to the body surface electrodes to compute both endocardial and epicardial voltage distributions.

Abstract: A method of repairing a three dimensional surface mesh model to be watertight and manifold generally includes identifying a plurality of hole edges in the surface mesh model, selecting one of the hole edges, creating a cycle of hole edges that defines a hole in the surface mesh model, converting the cycle of hole edges into two or more cycles of exactly three edges each, and adding a triangular facet to the surface mesh model for each of the cycles of exactly three edges. The process may be repeated until the model is substantially watertight. Non-manifold vertices may be repaired by selecting a vertex of the model, identifying a number of independent cycles of triangular facets sharing the selected vertex, and redefining the selected vertex for at least all but one of the number of independent cycles. This process may be repeated until the model is manifold.

Abstract: The instant invention relates to an electrophysiology apparatus and method used to measure electrical activity occurring in a portion of tissue of a patient and to visualize the electrical activity and/or information related to the electrical activity. In particular, the instant invention relates to three-dimensional mapping of the electrical activity and/or the information related to the electrical activity.

Abstract: The instant invention relates to an electrophysiology apparatus and method used to measure electrical activity occurring in a portion of tissue of a patient and to visualize the electrical activity and/or information related to the electrical activity. In particular, the instant invention relates to three-dimensional mapping of the electrical activity and/or the information related to the electrical activity.