Patents by Inventor Eric K. Sackmann

Eric K. Sackmann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR ASSAYING A MICRO-OBJECT WITHIN A MICROFLUIDIC DEVICE
    Publication number: 20230375447
    Abstract: The present disclosure relates to methods for assaying and controlling micro-objects in a microfluidic device. In situ-generated hydrogel barriers are provided for dividing a microfluidic chamber into areas where assaying a cell may be performed without interference from the presence of the cell itself.
    Type: Application
    Filed: March 27, 2023
    Publication date: November 23, 2023
    Inventors: Alexander J. MASTROIANNI, Peyton SHIEH, Kellen C. MOBILIA, Eric K. SACKMANN, Ke-Chih LIN, Or GADISH, Patrick N. INGRAM, Eric Chun-Jen SHIUE, Grayson Thomas WAWRZYN, Volker L.S. KURZ, Nathan J. VER HEUL, Randall D. LOWE, JR., Sara TAFOYA
  • Microfluidic devices for optically-driven convection and displacement, kits and methods thereof
    Patent number: 11802264
    Abstract: Apparatuses and methods are described for the use of optically driven bubble, convective and displacing fluidic flow to provide motive force in microfluidic devices. Alternative motive modalities are useful to selectively dislodge and displace micro-objects, including biological cells, from a variety of locations within the enclosure of a microfluidic device.
    Type: Grant
    Filed: October 12, 2020
    Date of Patent: October 31, 2023
    Assignee: PHENOMEX INC.
    Inventors: Volker L. S. Kurz, Troy A. Lionberger, Eric K. Sackmann, Kai W. Szeto, Paul M. Lebel, Brandon R. Bruhn, Keith J. Breinlinger, Eric D. Hobbs, Andrew W. McFarland, J. Tanner Nevill, Xiaohua Wang
  • LASER-ASSISTED REPOSITIONING OF A MICRO-OBJECT AND CULTURING OF AN ATTACHMENT-DEPENDENT CELL IN A MICROFLUIDIC ENVIRONMENT
    Publication number: 20220033758
    Abstract: Methods for laser-assisted repositioning of a micro-object and for culturing an attachment-dependent biological cell within a microfluidic device are described herein. Laser illumination is used to controllably create a bubble which repositions the micro-object. Further, methods of culturing an attachment-dependent biological cell are described, where the methods may include laser-assisted repositioning.
    Type: Application
    Filed: August 13, 2021
    Publication date: February 3, 2022
    Inventors: Eric K. SACKMANN, Nathan J. VER HEUL, Ryan M. COOPER, Alexander J. MASTROIANNI, Annamaria MOCCIARO, Vincent Haw Tien PAI, Randall D. LOWE, JR., Hector D. NEIRA-QUINTERO, Patrick N. INGRAM, Smriti SRIDHAR
  • SYSTEMS AND METHODS FOR IDENTIFICATION OF OPTIMIZED PROTEIN PRODUCTION AND KITS THEREFOR
    Publication number: 20210292751
    Abstract: Systems, methods, and kits therefor, enabling rapid protein evolution are described herein. A system useful in the methods described herein include a DNA synthesis component; a microfluidic system including a microfluidic device having a microfluidic channel and sequestration pens; and a computing component, which is configured to analyze assay results and, based upon the analysis, design improved DNA sequences for iterative protein evolution. The microfluidic system is configured to permit correlation of DNA sequence on a bead to its location within the microfluidic device, permit cell free protein expression of a DNA sequence captured to a bead, and to permit assay of the protein so produced.
    Type: Application
    Filed: April 9, 2021
    Publication date: September 23, 2021
    Applicant: BERKELEY LIGHTS, INC.
    Inventors: Jason M. McEWEN, Troy A. LIONBERGER, Eric K. SACKMANN, Volker L.S. KURZ, Kellen C. MOBILIA
  • Microfluidic Devices for Optically-Driven Convection and Displacement, Kits and Methods Thereof
    Publication number: 20210102150
    Abstract: Apparatuses and methods are described for the use of optically driven bubble, convective and displacing fluidic flow to provide motive force in microfluidic devices. Alternative motive modalities are useful to selectively dislodge and displace micro-objects, including biological cells, from a variety of locations within the enclosure of a microfluidic device.
    Type: Application
    Filed: October 12, 2020
    Publication date: April 8, 2021
    Inventors: Volker L.S. Kurz, Troy A. Lionberger, Eric K. Sackmann, Kai W. Szeto, Paul M. Lebel, Brandon R. Bruhn, Keith J. Breinlinger, Eric D. Hobbs, Andrew W. McFarland, J. Tanner Nevill, Xiaohua Wang
  • Microfluidic devices for optically-driven convection and displacement, kits and methods thereof
    Patent number: 10829728
    Abstract: Apparatuses and methods are described for the use of optically driven bubble, convective and displacing fluidic flow to provide motive force in microfluidic devices. Alternative motive modalities are useful to selectively dislodge and displace micro-objects, including biological cells, from a variety of locations within the enclosure of a microfluidic device.
    Type: Grant
    Filed: June 15, 2018
    Date of Patent: November 10, 2020
    Assignee: Berkeley Lights, Inc.
    Inventors: Volker L. S. Kurz, Troy A. Lionberger, Eric K. Sackmann, Kai W. Szeto, Paul M. Lebel, Brandon R. Bruhn, Keith J. Breinlinger, Eric D. Hobbs, Andrew W. McFarland, J. Tanner Nevill, Xiaohua Wang