Patents by Inventor Eric L. Zirbes

Eric L. Zirbes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the production of piperidine derivatives with microorganisms
    Patent number: 7691615
    Abstract: The present invention relates to the production of a product compound having a structure according to Formulae IA and/or IB: wherein n is 0 or 1; R1 is hydrogen or hydroxy; R2 is hydrogen; or, when n is 0, R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2, provided that when n is 1, R1 and R2 are each hydrogen; R3 is —COOH or —COOR4; R4 is an alkyl or aryl moiety; A, B, and D are the substituents of their rings, each of which may be different or the same, and are selected from the group consisting of hydrogen, halogens, alkyl, hydroxy, and alkoxy. This process involves incubating a starting compound having a structure according to Formulae IIA and/or IIB: wherein R3 is —CH3 and R1, R2, A, B, and D are defined above in the presence of a microorganism under conditions effective to produce the product compound.
    Type: Grant
    Filed: January 17, 2007
    Date of Patent: April 6, 2010
    Assignee: Albany Molecular Research, Inc.
    Inventors: Peter C. Michels, Eric L. Zirbes
  • Process for the production of piperidine derivatives with microorganisms
    Patent number: 7232908
    Abstract: The present invention relates to a process for the production of piperidine derivatives with microorganisms. This is carried out by incubating starting compounds in the presence of a microorganism under conditions effective to produce piperidine derivative products. Suitable microorganisms can be from any one of the genus of Stemphylium, Gliocladium, Bacillus, Botrytis, Cyathus, Rhizopus, Pycniodosphora, Pseudomonas, Helicostylum, Mucor, Gelasinospora, Rhodotorula, Candida, Mycobacterium, and Penicillium. In another aspect of the invention, starting compounds are incubated in the presence of Cunninghamella bainieria under conditions effective to produce piperidine derivative products.
    Type: Grant
    Filed: August 11, 2003
    Date of Patent: June 19, 2007
    Assignee: AMR Technology, Inc.
    Inventors: Peter C. Michels, Eric L. Zirbes
  • Process for the production of piperidine derivatives with microorganisms
    Patent number: 6613907
    Abstract: The present invention relates to the production of a product compound having a structure according to Formulae IA and/or IB: wherein n is 0 or 1; R1 is hydrogen or hydroxy; R2 is hydrogen; or, when n is 0, R1 and R2 taken together form a second bond between the carbon atoms bearing R1 and R2, provided that when n is 1, R1 and R2 are each hydrogen; R3 is —COOH or —COOR4; R4 is an alkyl or aryl moiety; A, B, and D are the substituents of their rings, each of which may be different or the same, and are selected from the group consisting of hydrogen, halogens, alkyl, hydroxy, and alkoxy. This process involves incubating a starting compound having a structure according to Formulae IIA and/or IIB: wherein R3 is —CH3 and R1, R2, A, B, and D are defined above In the presence of a microorganism under conditions effective to produce the product compound.
    Type: Grant
    Filed: January 4, 2001
    Date of Patent: September 2, 2003
    Assignee: AMR Technology, Inc.
    Inventors: Peter C. Michels, Eric L. Zirbes
  • Process for the production of piperidine derivatives with microorganisms
    Publication number: 20020087003
    Abstract: The present invention relates to the production of a product compound having a structure according to Formulae IA and/or IB: 1
    Type: Application
    Filed: January 4, 2001
    Publication date: July 4, 2002
    Inventors: Peter C. Michels, Eric L. Zirbes