Patents by Inventor Eric Lader

Eric Lader has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DEPLETING UNWANTED RNA SPECIES
    Publication number: 20210324377
    Abstract: The present disclosure provides methods and kits for inhibiting cDNA synthesis of unwanted RNA species during reverse transcription. The methods and kits provided herein use blocking oligonucleotides such as those comprising locked nucleic acids (LNAs).
    Type: Application
    Filed: September 19, 2019
    Publication date: October 21, 2021
    Inventors: Jonathan Shaffer, Eric Lader, Niels Tolstrup, Joerg Krummheuer, Daniel Y. Kim, Sascha Strauss
  • Modified siNA
    Patent number: 9422552
    Abstract: The present invention pertains to the use of at least one abasic modification within the first 8 nucleotide positions of the 5? region of the antisense strand of a small interfering nucleic acid (siNA) molecule for reducing off-target effects. Provided are suitable modified siNAs, compositions and methods for producing respective siNAs, as well as kits comprising respective siNAs.
    Type: Grant
    Filed: June 11, 2010
    Date of Patent: August 23, 2016
    Assignee: QIAGEN GMBH
    Inventors: Peter Hahn, Eric Lader, Wolfgang Bielke, Alexander Azzawi, Jie Kang
  • METHODS AND REAGENTS FOR PRESERVING RNA IN CELL AND TISSUE SAMPLES
    Publication number: 20140295411
    Abstract: This specification relates to the field of molecular biology and provides novel methods and reagents for preserving and protecting the ribonucleic acid (RNA) content of samples from degradation prior to RNA isolation. This preservation may be accomplished without ultra-low temperature storage or disruption of the tissue.
    Type: Application
    Filed: March 17, 2014
    Publication date: October 2, 2014
    Applicant: APPLIED BIOSYSTEMS, LLC
    Inventor: Eric LADER
  • Apoptosis inducing positive control for expression modulation experiments
    Patent number: 8367320
    Abstract: The invention pertains to a method for performing an expression modulating analysis or assay, wherein an apoptosis inducing expression modulating compound targeting a repetitive element present in the untranslated region, in particular the 3? UTRs of protein coding gene transcripts is introduced into cells to induce apoptosis in the cells as a positive control. Also provided are suitable kits and compositions.
    Type: Grant
    Filed: December 29, 2008
    Date of Patent: February 5, 2013
    Assignee: Qiagen Sciences, Inc.
    Inventor: Eric Lader
  • APOPTOSIS INDUCING POSITIVE CONTROL FOR EXPRESSION MODULATION EXPERIMENTS
    Publication number: 20100285484
    Abstract: The invention pertains to a method for performing an expression modulating analysis or assay, wherein an apoptosis inducing expression modulating compound targeting a repetitive element present in the untranslated region, in particular the 3? UTRs of protein coding gene transcripts is introduced into cells to induce apoptosis in the cells as a positive control. Also provided are suitable kits and compositions.
    Type: Application
    Filed: December 29, 2008
    Publication date: November 11, 2010
    Applicant: QIAGEN SCIENCES, INC.
    Inventor: Eric Lader
  • Method for the reverse transcription and/or amplification of nucleic acids
    Publication number: 20060281092
    Abstract: The present invention relates to a process for the reverse transcription and/or amplification of a product from a reverse transcription of a pool of nucleic acids of a specific type, this pool of nucleic acids originating from a complex biological sample or an enzymatic reaction.
    Type: Application
    Filed: July 26, 2004
    Publication date: December 14, 2006
    Inventors: Tanja Wille, Christian Korfhage, Eric Lader