Abstract: A multi-lumen needle and catheter guidance system is provided and includes: a multi-lumen needle including a pair of rectangular lumens, the pair of rectangular lumens extending longitudinally within and through a shaft of the multi-lumen needle from a proximal end of the multi-lumen needle to a distal end of the multi-lumen needle, the pair of rectangular lumens diverging in opposite directions and ending at a pair of rectangular apertures formed on opposing sides of the distal end of the multi-lumen needle; and a pair of rectangular catheters for insertion into and through the pair of lumens, wherein distal ends of the rectangular catheters are configured to pass out of the distal end of the multi-lumen needle in opposing directions through the pair of rectangular apertures.