Abstract: A device for converting the wavelength of electromagnetic radiation is disclosed. In an embodiment the device includes a carrier, a conversion layer configured to at least partly convert a wavelength of the electromagnetic radiation and an intermediate layer, wherein the conversion layer is connected to the carrier via the intermediate layer, and wherein the intermediate layer, at least in partial regions, includes a solid layer and a connection layer.

Abstract: Cenicriviroc (CVC) is an orally active antagonist of ligand binding to C-C chemokine receptor type 5 (CCR5) and C-C chemokine receptor type 2 (CCR2). CVC blocks the binding of RANTES, MIP-1?, and MIP-1? to CCR5, and of MCP-1/CCL2 to CCR2. Methods of treating fibrosis and related conditions comprising co-administration of CVC with FXR agonists, high dose vitamin E (>400 iU/d), a peroxisome proliferator-activated receptor alpha (PPAR-?) agonist, PPAR-? agonist, PPAR-? agonist and/or chemokine antagonists are provided herein.

Abstract: The present disclosure provides methods of treating fibrosis or a fibrotic disease or condition in a subject in need thereof comprising administering to the subject a therapeutically effective amount of cenicriviroc or a salt or solvate thereof. The fibrosis or fibrotic disease may be liver fibrosis, renal fibrosis, non-cirrhotic hepatic fibrosis, associated with non-alcoholic steatohepatitis (NASH), non-alcoholic fatty liver disease (NAFLD), or emerging cirrhosis.

Abstract: Cenicriviroc (CVC) is an orally active antagonist of ligand binding to C—C chemokine receptor type 5 (CCR5) and C—C chemokine receptor type 2 (CCR2). CVC blocks the binding of RANTES, MIP-1?, and MIP-1? to CCR5, and of MCP-1/CCL2 to CCR2. Methods of treating HIV-2 infection and related conditions comprising administration of CVC are provided herein.

Abstract: A remote-controlled ultrasound device including an enclosure envelope containing a tight compartment and a control compartment that are tightly separated by a transverse partition. Sensor means are designed so as to move in the tight compartment, submerged in an ultrasonic-wave-propagating medium, and driving means are arranged in the control compartment for triggering the movement of a support rod at the end of which are mounted the sensor means. The support rod extends through the partition in order to connect the driving means and the sensor means, being mounted in a freely rotational manner inside a tube passing through said partition. The invention is especially applicable to remote ultrasound operations in the medical field.

Abstract: In a sectional overhead garage door assembly, the problem of inefficient and/or insufficient insulation of a garage door assembly that comprises a door for closing an entrance is solved by covering joints and openings of the door assembly with isolating members so that the joints and openings of the door assembly other than the entrance remain close when the door is opened. For example, an embodiment of an insulation system includes a lateral insulating assembly to be secured to a door frame or wall adjacent the garage door; and a resilient insulating assembly is secured to at least one of the garage door along the lateral edge thereof and the lateral insulating assembly for defining an enclosure with the garage door and the lateral insulating assembly. In some embodiment, each door panel is provided with a door panel insulating assembly.

Abstract: A turbomachine vane damper constructed so as to be housed between the lower face of the platforms of two adjacent turbomachine vanes and the rim of the rotor disk on which the vanes are mounted is disclosed. The damper includes a weight, a bearing plate and a spring. The spring connects the weight to the bearing plate.

Abstract: The present invention relates to a turbomachine vane damper constructed so as to be housed between the lower face of the platforms of two adjacent turbomachine vanes and the rim of the rotor disk on which the vanes are mounted. This damper is noteworthy in that it comprises a weight (11), a bearing plate (13) and a spring (12), the spring connecting the weight to the bearing plate.

Abstract: A device for the positioning of a blade in a slot of a rotor disk includes a spring spacer that consists of a single elastic piece of profiled shape with a top wall and a bottom wall connected together by two side walls. The two side walls include at least one machined feature.

Abstract: Method of calibrating the mass of components intended to be mounted at the periphery of a rotor A method of calibrating the mass of components intended to be mounted at the periphery of a rotor, the method consisting, for each of the components, in removing by machining a volume of material in a region of the component situated on one of its axes of inertia in order to bring the mass of the component to a predetermined value.

Abstract: A device for the positioning of a blade in a slot of a rotor disk includes a spring spacer that consists of a single elastic piece of profiled shape with a top wall and a bottom wall connected together by two side walls. The two side walls include at least one machined feature.