Patents by Inventor Eric Leslie Bell

Eric Leslie Bell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11771658
    Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, ethylenediaminedisuccinic acid, an oxidant, water, and optionally citric acid, is provided along with temperature conditions to directly form within the reaction mixture, a stable dispersion of cerium oxide nanoparticles. Biocompatible nanoparticles comprised of cerium oxide, ethylenediaminedisuccinic acid, and optionally citric acid, are described. An increase in catalase-like enzyme activity is demonstrated by cerium oxide nanoparticles prepared with citric acid and ethylenediaminedisuccinic acid.
    Type: Grant
    Filed: December 9, 2021
    Date of Patent: October 3, 2023
    Assignee: Cerion, LLC
    Inventor: Eric Leslie Bell
  • Publication number: 20220096392
    Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, ethylenediaminedisuccinic acid, an oxidant, water, and optionally citric acid, is provided along with temperature conditions to directly form within the reaction mixture, a stable dispersion of cerium oxide nanoparticles. Biocompatible nanoparticles comprised of cerium oxide, ethylenediaminedisuccinic acid, and optionally citric acid, are described. An increase in catalase-like enzyme activity is demonstrated by cerium oxide nanoparticles prepared with citric acid and ethylenediaminedisuccinic acid.
    Type: Application
    Filed: December 9, 2021
    Publication date: March 31, 2022
    Applicant: Cerion, LLC
    Inventor: Eric Leslie Bell
  • Publication number: 20200345650
    Abstract: A process for making nanoparticles of biocompatible materials, wherein an aqueous reaction mixture comprising cerous ion, ethylenediaminedisuccinic acid, an oxidant, water, and optionally citric acid, is provided along with temperature conditions to directly form within the reaction mixture, a stable dispersion of cerium oxide nanoparticles. Also, biocompatibe nanoparticles comprised of cerium oxide, ethyenediaminedisuccinic acid, and optionally citric acid. An increase in catalase-like enzyme activity is demonstrated by cerium oxide nanoparticles prepared with citric acid and ethylenediaminedisuccinic acid.
    Type: Application
    Filed: May 28, 2020
    Publication date: November 5, 2020
    Applicant: Cerion, LLC
    Inventor: Eric Leslie Bell
  • Patent number: 10729717
    Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid and ethylenediaminetetraacetic acid in a predetermined ratio, an oxidant, and water is provided along with temperature conditions to directly form, without isolation, a stable dispersion of cerium oxide nanoparticles. These biocompatible cerium oxide nanoparticles may be used to prevent and/or treat oxidative stress related diseases, such as stroke, relapse/remitting multiple sclerosis, chronic-progressive multiple sclerosis, amyotrophic lateral sclerosis, and ischemic reperfusion injury.
    Type: Grant
    Filed: May 7, 2018
    Date of Patent: August 4, 2020
    Assignee: Cerion Enterprises LLC
    Inventors: Kenneth Joseph Reed, Wendi Ann Costanzo, Joseph Samuel Erlichman, Eric Leslie Bell
  • Patent number: 10722474
    Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, ethylenediaminedisuccinic acid, an oxidant, water, and optionally citric acid, is provided along with temperature conditions to directly form within the reaction mixture, a stable dispersion of cerium oxide nanoparticles. Biocompatible, nanoparticles comprised of cerium oxide, ethylenediaminedisuccinic acid, and optionally citric acid, are described. An increase in catalase-like enzyme activity is demonstrated by cerium oxide nanoparticles prepared with citric acid and ethylenediaminedisuccinic acid.
    Type: Grant
    Filed: January 20, 2016
    Date of Patent: July 28, 2020
    Assignee: Cerion, LLC
    Inventor: Eric Leslie Bell
  • Publication number: 20180325832
    Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, ethylenediaminedisuccinic acid, an oxidant, water, and optionally citric acid, is provided along with temperature conditions to directly form within the reaction mixture, a stable dispersion of cerium oxide nanoparticles. Biocompatible, nanoparticles comprised of cerium oxide, ethylenediaminedisuccinic acid, and optionally citric acid, are described. An increase in catalase-like enzyme activity is demonstrated by cerium oxide nanoparticles prepared with citric acid and ethylenediaminedisuccinic acid.
    Type: Application
    Filed: January 20, 2016
    Publication date: November 15, 2018
    Applicant: Cerion, LLC
    Inventor: Eric Leslie Bell
  • Publication number: 20180250333
    Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid and ethylenediaminetetraacetic acid in a predetermined ratio, an oxidant, and water is provided along with temperature conditions to directly form, without isolation, a stable dispersion of cerium oxide nanoparticles. These biocompatible cerium oxide nanoparticles may be used to prevent and/or treat oxidative stress related diseases, such as stroke, relapse/remitting multiple sclerosis, chronic-progressive multiple sclerosis, amyotrophic lateral sclerosis, and ischemic reperfusion injury.
    Type: Application
    Filed: May 7, 2018
    Publication date: September 6, 2018
    Applicant: CERION, LLC
    Inventors: Kenneth Joseph Reed, Wendi Ann Costanzo, Joseph Samuel Erlichman, Eric Leslie Bell
  • Patent number: 9962406
    Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid and ethylenediaminetetraacetic acid in a predetermined ratio, an oxidant, and water is provided along with temperature conditions to directly form, without isolation, a stable dispersion of cerium oxide nanoparticles. These biocompatible cerium oxide nanoparticles may be used to prevent and/or treat oxidative stress related diseases, such as stroke, relapse/remitting multiple sclerosis, chronic-progressive multiple sclerosis, amyotrophic lateral sclerosis, and ischemic reperfusion injury.
    Type: Grant
    Filed: December 22, 2016
    Date of Patent: May 8, 2018
    Assignee: CERION, LLC
    Inventors: Kenneth Joseph Reed, Wendi Ann Costanzo, Joseph Samuel Erlichman, Eric Leslie Bell
  • Publication number: 20170100430
    Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid and ethylenediaminetetraacetic acid in a predetermined ratio, an oxidant, and water is provided along with temperature conditions to directly form, without isolation, a stable dispersion of cerium oxide nanoparticles. These biocompatible cerium oxide nanoparticles may be used to prevent and/or treat oxidative stress related diseases, such as stroke, relapse/remitting multiple sclerosis, chronic-progressive multiple sclerosis, amyotrophic lateral sclerosis, and ischemic reperfusion injury.
    Type: Application
    Filed: December 22, 2016
    Publication date: April 13, 2017
    Applicant: CERION, LLC
    Inventors: KENNETH JOSEPH REED, WENDI ANN COSTANZO, JOSEPH SAMUEL ERLICHMAN, ERIC LESLIE BELL
  • Patent number: 9533007
    Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid and ethylenediaminetetraacetic acid in a predetermined ratio, an oxidant, and water is provided along with temperature conditions to directly form, without isolation, a stable dispersion of cerium oxide nanoparticles. These biocompatible cerium oxide nanoparticles may be used to prevent and/or treat oxidative stress related diseases, such as stroke, relapse/remitting multiple sclerosis, chronic-progressive multiple sclerosis, amyotrophic lateral sclerosis, and ischemic reperfusion injury.
    Type: Grant
    Filed: April 20, 2015
    Date of Patent: January 3, 2017
    Assignee: CERION, LLC
    Inventors: Kenneth Joseph Reed, Wendi Ann Costanzo, Joseph Samuel Erlichman, Eric Leslie Bell
  • Publication number: 20150231174
    Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid and ethylenediaminetetraacetic acid in a predetermined ratio, an oxidant, and water is provided along with temperature conditions to directly form, without isolation, a stable dispersion of cerium oxide nanoparticles. These biocompatible cerium oxide nanoparticles may be used to prevent and/or treat oxidative stress related diseases, such as stroke, relapse/remitting multiple sclerosis, chronic-progressive multiple sclerosis, amyotrophic lateral sclerosis, and ischemic reperfusion injury.
    Type: Application
    Filed: April 20, 2015
    Publication date: August 20, 2015
    Applicant: CERION, LLC
    Inventors: Kenneth Joseph Reed, Wendi Ann Costanzo, Joseph Samuel Erlichman, Eric Leslie Bell
  • Patent number: 9034392
    Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid and ethylenediaminetetraacetic acid in a predetermined ratio, an oxidant, and water is provided along with temperature conditions to directly form, without isolation, a stable dispersion of cerium oxide nanoparticles. These biocompatible cerium oxide nanoparticles may be used to prevent and/or treat oxidative stress related diseases, such as stroke, relapse/remitting multiple sclerosis, chronic-progressive multiple sclerosis, amyotrophic lateral sclerosis, and ischemic reperfusion injury.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: May 19, 2015
    Assignee: CERION, LLC
    Inventors: Kenneth Joseph Reed, Wendi Ann Costanzo, Joseph Samuel Erlichman, Eric Leslie Bell
  • Publication number: 20130337083
    Abstract: A process for making nanoparticles of biocompatible materials is described, wherein an aqueous reaction mixture comprising cerous ion, citric acid and ethylenediaminetetraacetic acid in a predetermined ratio, an oxidant, and water is provided along with temperature conditions to directly form, without isolation, a stable dispersion of cerium oxide nanoparticles. These biocompatible cerium oxide nanoparticles may be used to prevent and/or treat oxidative stress related diseases, such as stroke, relapse/remitting multiple sclerosis, chronic-progressive multiple sclerosis, amyotrophic lateral sclerosis, and ischemic reperfusion injury.
    Type: Application
    Filed: March 15, 2013
    Publication date: December 19, 2013
    Applicant: Cerion Enterprises, LLC
    Inventors: Kenneth Joseph Reed, Wendi Ann Costanzo, Joseph Samuel Erlichman, Eric Leslie Bell
  • Patent number: 5792601
    Abstract: A radiation sensitive emulsion is disclosed containing iridium doped composite silver halide grains comprised of (a) host portions having an average aspect ratio of less than 1.3 and consisting essentially of monodisperse silver iodochloride grains containing from 0.05 to 3 mole percent iodide, based on total silver forming the host portions, with maximum iodide concentrations located nearer the surface of the host portions than their center and (b) epitaxially deposited portions containing the iridium dopant and silver bromide accounting for from 0.1 to 5 mole percent of total silver forming the composite grains.The emulsions are prepared by (a) first providing an emulsion containing grains which form the host portions of the grains and (b) modifying the performance properties of the host grains by a combination of silver bromide addition, iridium dopant incorporation and antifoggant addition, in which, prior to antifoggant addition, silver bromide in the amount of from 0.1 to 5.
    Type: Grant
    Filed: July 29, 1996
    Date of Patent: August 11, 1998
    Assignee: Eastman Kodak Company
    Inventors: James Lawrence Edwards, Benjamin Teh-Kung Chen, Eric Leslie Bell, Roger Lok