Patents by Inventor Eric Lodewijk

Eric Lodewijk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Resolution of ibuprofen
    Patent number: 5621140
    Abstract: (S)-ibuprofen may be separated from a mixture of (S)-ibuprofen and (R)-ibuprofen in high yield and enantiomeric purity in a single resolution step using an N-alkyl-D-glucamine as the resolving agent.
    Type: Grant
    Filed: December 22, 1994
    Date of Patent: April 15, 1997
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: George C. Schloemer, Eric Lodewijk, Gregory P. Withers
  • Preparation of N-9 substituted guanine compounds
    Patent number: 5565565
    Abstract: The invention relates to efficient and selective processes for the synthesis of the antiviral N-9 substituted guanine compounds acyclovir and ganciclovir.
    Type: Grant
    Filed: August 4, 1994
    Date of Patent: October 15, 1996
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Eric Lodewijk, Yeun-Kwei Han, George C. Schloemer, Sam L. Nguyen
  • 2-(2-nitrovinyl)thiophene reduction and synthesis of thieno[3,2-c]pyridine derivatives
    Patent number: 4906756
    Abstract: An improved process for the reduction of 2-(2-nitrovinyl)thiophene to form 2-(2-thienyl)ethylamine employs a boron-containing reducing agent, preferably diborane. The 2-(2-thienyl)ethylamine produced by this process is advantageously converted to ticlopidine.
    Type: Grant
    Filed: May 10, 1988
    Date of Patent: March 6, 1990
    Assignee: Syntex (U.S.A.) Inc.
    Inventors: Eric Lodewijk, Hiralal N. Khatri