Patents by Inventor Eric M. Scholar

Eric M. Scholar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Phosphorothioate inhibitors of metastatic breast cancer
    Patent number: 5552390
    Abstract: A method of inhibiting tumor invasion and metastasis of cancer cells using antisense oligonucleotides is disclosed. Phosphorothioate oligos were developed which are complementary to proteolytic enzymes such as urokinase plasminogen activator which are associated with invasion. In vitro and in vivo experiments with these oligos demonstrated highly significant reduction in tumor invasion and metastasis of mammary carcinoma cells.
    Type: Grant
    Filed: December 9, 1993
    Date of Patent: September 3, 1996
    Assignee: The Board of Regents of The University of Nebraska
    Inventors: Eric M. Scholar, Patrick L. Iversen