Patents by Inventor Eric M. Simmons

Eric M. Simmons has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Decorative nonwoven laminates
    Patent number: 11958273
    Abstract: A decorative, nonwoven laminate and a method of forming, including a first side of a first nonwoven affixed to one or both of a) a first side of a polymeric sheet or b) a second nonwoven, wherein the first nonwoven exhibits a basis weight of 15 g/m2 to 2500 g/m2 and the second nonwoven exhibits a basis weight of 15 g/m2 to 1200 g/m2; and a colorant deposited on a second side of the first nonwoven. A topical coating may or may not be applied to improve durability of the printed surface layer. The decorative nonwoven laminate may also amount to a single layer of the first nonwoven, which then includes a layer of colorant and a topical coating over the colorant and single nonwoven layer.
    Type: Grant
    Filed: September 6, 2019
    Date of Patent: April 16, 2024
    Assignee: AURIA SOLUTIONS UK I LTD.
    Inventors: Kenneth Mitchell Whitesell, Jr., Sean Bracken Simmons, Ernest Franklin Wilson, Tyler M. Heath, Timothy J. Allison, Eric Staudt
  • Substituted 4-amino-1H-imidazo[4,5-c]quinoline compounds and improved methods for their preparation
    Patent number: 11827597
    Abstract: Improved methods and intermediates thereof for preparing substituted 4-amino-1H-imidazo[4,5-c]quinoline compounds are described. These compounds are useful as NLRP3 modulators.
    Type: Grant
    Filed: November 22, 2022
    Date of Patent: November 28, 2023
    Assignee: INNATE TUMOR IMMUNITY, INC.
    Inventors: Sha Lou, Adrian Ortiz, Christopher Robert Jamison, Eric M. Simmons
  • SYNTHESIS OF 1,2,5-TRI-O-BENZOYL-3-DIBENZYLAMINO-3-DEOXYRIBOSE AS INTERMEDIATE FOR PRODUCING 3'-AMINO-3'-DEOXYADENOSINE AND 3'-AMINO-3'-DEOXYGUANOSINE AND THE PROTECTED DERIVATIVES THEREOF
    Publication number: 20230357306
    Abstract: The invention generally relates to improved processes for the preparation of intermediates of a cyclic dinucleotide which is useful as a STING agonist.
    Type: Application
    Filed: February 5, 2020
    Publication date: November 9, 2023
    Inventors: Changxia Yuan, Michael Anthony Schmidt, Adrian Ortiz, Amanda J. Rogers, Jason J. Zhu, Zhongmin Xu, Miao Yu, Eric M. Simmons, Shulin Wu
  • PROCESS FOR THE PREPARATION OF 6-(CYCLOPROPANEAMIDO)-4-((2-METHOXY-3-(1-METHYL-1H-1,2,4-TRIAZOL-3-YL)PHENYL)AMINO)-N-(METHYL-D3)PYRIDAZINE-3-CARBOXAMIDE
    Publication number: 20230271946
    Abstract: The invention relates to an improved process for synthesizing 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-5N-(methyl-d3)pyridazine-3-carboxamide of the formula: Compound I is currently in clinical trials for the treatment of auto-immune and auto-inflammatory diseases such as psoriasis.
    Type: Application
    Filed: April 13, 2023
    Publication date: August 31, 2023
    Inventors: Ke Chen, Joerg Deerberg, Dong Lin, Michael Dummeldinger, Bahar Inankur, Sergei Kolotuchin, Jun Li, Amanda J. Rogers, Victor W. Rosso, Eric M. Simmons, Maxime C.D. Soumeillant, Daniel S. Treitler, Jianji Wang, Bin Zheng, Michael J. Smith, Neil A. Strotman, Steven Tymonko, Tamas Benkovics
  • SUBSTITUTED 4-AMINO-1H-IMIDAZO[4,5-c]QUINOLINE COMPOUNDS AND IMPROVED METHODS FOR THEIR PREPARATION
    Publication number: 20230097144
    Abstract: Improved methods and intermediates thereof for preparing substituted 4-amino-1H-imidazo[4,5-c]quinoline compounds are described. These compounds are useful as NLRP3 modulators.
    Type: Application
    Filed: November 22, 2022
    Publication date: March 30, 2023
    Inventors: Sha Lou, Adrian Ortiz, Christopher Robert Jamison, Eric M. Simmons
  • NOVEL SYNTHETIC OPTIONS TOWARDS THE MANUFACTURE OF (6R,10S)-10-{4-[5-CHLORO-2-(4-CHLORO-1H-1,2,3-TRIAZOL-1-YL)PHENYL]-6-OXO-1(6H)-PYRIMIDINYL}- 1-(DIFLUOROMETHYL)-6-METHYL-1,4,7,8,9,10-HEXAHYDRO-11,15-(METHENO)PYRAZOLO[4,3-B][1,7]DIAZACYCLOTETRADECIN-5(6H)-ONE
    Publication number: 20220144836
    Abstract: Highly efficient methods are provided for preparing key intermediates in the synthesis of Compound (I), which are broadly applicable and can provide selected components having a variety of substituents groups.
    Type: Application
    Filed: April 10, 2020
    Publication date: May 12, 2022
    Inventors: Nicolas CUNIERE, Yu FAN, Sergei KOLUTUCHIN, Subha MUKHERJEE, Eric M. SIMMONS, Amarjit SINGH, Carolyn S. WEI, Yi XIAO, Changxia YUAN, Bin ZHENG, Simon Albert WAGSCHAL, Diego Fernando Domenico BROGGINI, Duy Chi Trung CAO, Kostiantyn CHERNICHENKO, Sebastien Francois Emmanuel LEMAIRE, Cyril BEN HAÏM
  • SUBSTITUTED 4-AMINO-1H-IMIDAZO[4,5-c]QUINOLINE COMPOUNDS AND IMPROVED METHODS FOR THEIR PREPARATION
    Publication number: 20210332040
    Abstract: Improved methods and intermediates thereof for preparing substituted 4-amino-1H-imidazo[4,5-c]quinoline compounds are described. These compounds are useful as NLRP3 modulators.
    Type: Application
    Filed: August 15, 2019
    Publication date: October 28, 2021
    Inventors: Sha Lou, Adrian Ortiz, Rebecca A. Green, Christopher Robert Jamison, Candice Lee Joe, Sergei Kolotuchin, Eric M. Simmons, Neil A. Strotman, Matthew W. Haley, Yichen Tan, Andrew William Glace, Dong Lin, Albert J. DelMonte, Peng Geng, Bahar Inankur, Victor W. Rosso, Mansi S. Shah
  • PROCESS FOR THE PREPARATION OF 6-(CYCLOPROPANEAMIDO)-4-((2-METHOXY-3-(1-METHYL-1H-1,2,4-TRIAZOL-3-YL)PHENYL)AMINO)-N-(METHYL-D3)PYRIDAZINE-3-CARBOXAMIDE
    Publication number: 20210107897
    Abstract: The invention relates to an improved process for synthesizing 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide of the formula: Compound I is currently in clinical trials for the treatment of auto-immune and auto-inflammatory diseases such as psoriasis.
    Type: Application
    Filed: December 22, 2020
    Publication date: April 15, 2021
    Inventors: Ke Chen, Joerg Deerberg, Dong Lin, Michael Dummeldinger, Bahar Inankur, Sergei Kolotuchin, Jun Li, Amanda J. Rogers, Victor W. Rosso, Eric M. Simmons, Maxime C.D. Soumeillant, Daniel S. Treitler, Jianji Wang, Bin Zheng, Michael J. Smith, Neil A. Strotman, Steven Tymonko, Tamas Benkovics
  • Process for the preparation of 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide
    Patent number: 10899745
    Abstract: The invention relates to an improved process for synthesizing 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide of the formula: [INSERT CHEMICAL STRUCTURE HERE] Compound I is currently in clinical trials for the treatment of auto-immune and auto-inflammatory diseases such as psoriasis.
    Type: Grant
    Filed: March 29, 2018
    Date of Patent: January 26, 2021
    Assignee: Bristol-Myers Squibb Company
    Inventors: Ke Chen, Joerg Deerberg, Dong Lin, Michael Dummeldinger, Bahar Inankur, Sergei Kolotuchin, Jun Li, Amanda J. Rogers, Victor W. Rosso, Eric M. Simmons, Daniel S. Treitler, Jianji Wang, Michael J. Smith, Tamas Benkovics
  • PROCESS FOR THE PREPARATION OF 6-(CYCLOPROPANEAMIDO)-4-((2-METHOXY-3-(1-METHYL-1H-1,2,4-TRIAZOL-3-YL)PHENYL)AMINO)-N-(METHYL-D3)PYRIDAZINE-3-CARBOXAMIDE
    Publication number: 20200109134
    Abstract: The invention relates to an improved process for synthesizing 6-(cyclopropaneamido)-4-((2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)phenyl)amino)-N-(methyl-d3)pyridazine-3-carboxamide of the formula: [INSERT CHEMICAL STRUCTURE HERE] Compound I is currently in clinical trials for the treatment of auto-immune and auto-inflammatory diseases such as psoriasis.
    Type: Application
    Filed: March 29, 2018
    Publication date: April 9, 2020
    Inventors: Ke Chen, Joerg Deerberg, Dong Lin, Michael Dummeldinger, Bahar Inankur, Sergei Kolotuchin, Jun Li, Amanda J. Rogers, Victor W. Rosso, Eric M. Simmons, Maxime C.D. Soumeillant, Daniel S. Treitler, Jianji Wang, Bin Zheng, Michael J. Smith, Neil A. Strotman, Steven Tymonko, Tamas Benkovics