Patents by Inventor Eric Manginot

Eric Manginot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL PROCESSES FOR THE PRODUCTION OF USEFUL INTERMEDIATES
    Publication number: 20100168426
    Abstract: The present application relates to a new process for the asymmetric production of 3-(pyridin-4-yl)-3-hydroxy-pentanoic acid derivatives, which are useful intermediates in the manufacture of compounds that are known to show antiproliferative activity.
    Type: Application
    Filed: March 8, 2010
    Publication date: July 1, 2010
    Applicant: Ipsen/S.C.R.A.S. (Andre Bourgouin)
    Inventors: Christian Diolez, Eric Manginot, Rene Peters, Alain Rolland, Marc Veyrat
  • Processes for the production of useful intermediates
    Patent number: 7705155
    Abstract: The present application relates to a new process for the asymmetric production of 3-(pyridin-4-yl)-3-hydroxy-pentanoic acid derivatives, which are useful intermediates in the manufacture of compounds that are known to show antiproliferative activity.
    Type: Grant
    Filed: March 21, 2007
    Date of Patent: April 27, 2010
    Assignee: Societe de Conseils de Recherches et D'Applications Scientifiques
    Inventors: Christian Diolez, Eric Manginot, Rene Peters, Alain Rolland, Marc Veyrat
  • Novel Processes for the Production of Useful Intermediates
    Publication number: 20090247563
    Abstract: The present application relates to a new process for the asymmetric production of 3-(pyridin-4-yl)-3-hydroxy-pentanoic acid derivatives, which are useful intermediates in the manufacture of compounds that are known to show antiproliferative activity.
    Type: Application
    Filed: March 21, 2007
    Publication date: October 1, 2009
    Applicant: Ipsen/S.C.R.A.S. (Andre Bourgouin)
    Inventors: Christian DIOLEZ, Eric Manginot, Rene Peters, Alain Rolland, Marc Veyrat
  • Novel Processes for the Production of Useful Intermediates
    Publication number: 20070167475
    Abstract: The present application relates to a new process for the asymmetric production of 3-(pyridin-4-yl)-3-hydroxy-pentanoic acid derivatives, which are useful intermediates in the manufacture of compounds that are known to show antiproliferative activity.
    Type: Application
    Filed: March 21, 2007
    Publication date: July 19, 2007
    Applicant: Ipsen/S.C.R.A.S. (Andre Bourgouin)
    Inventors: Christian DIOLEZ, Eric Manginot, Rene Peters, Alain Rolland, Marc Veyrat
  • Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 7135478
    Abstract: A compound of the formula wherein the substituents are defined as in the specification which compounds are useful in the treatment of cancer.
    Type: Grant
    Filed: August 31, 2004
    Date of Patent: November 14, 2006
    Assignee: Societe de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gérard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 7053102
    Abstract: Compositions for treating cancer comprising an amount of a camptothecin with a 7-ring ?-hydroxy lactone ring of the formula wherein the substituents are defined as in the specification sufficient to treat cancer.
    Type: Grant
    Filed: June 7, 2004
    Date of Patent: May 30, 2006
    Assignee: Societe de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Method for preparing disodium 2,2'-dithiobis(ethanesulphonate)
    Patent number: 6936733
    Abstract: The invention concerns a novel method for industrial preparation of disodium 2,2?-dithiobis(alkylsulphonates), and in particular disodium 2,2?-dithiobis(ethanesulphate) (dimesna). Said novel method is summarized by the reaction diagram (A). In diagram (A), Hal represents a halogen atom, and preferably a bromine atom; M represents a sodium or potassium atom; and n represents an integer ranging between 0 and 2.
    Type: Grant
    Filed: July 17, 2001
    Date of Patent: August 30, 2005
    Assignee: BioNumerik Pharmaceuticals, Inc.
    Inventors: Jean-Bernard Cazaux, Eric Manginot, Marc Veyrat
  • New analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Publication number: 20050038064
    Abstract: A compound of the formula wherein the substituents are defined as in the specification which compounds are useful in the treatment of cancer.
    Type: Application
    Filed: August 31, 2004
    Publication date: February 17, 2005
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • New analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Publication number: 20040254163
    Abstract: Compositions for treating cancer comprising an amount of a camptothecin with a 7-ring &bgr;-hydroxy lactone ring of the formula 1
    Type: Application
    Filed: June 7, 2004
    Publication date: December 16, 2004
    Applicant: SOCIETE DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 6815546
    Abstract: A compound of the formula wherein the substituents are defined as in the specification which compounds are useful in the treatment of cancer.
    Type: Grant
    Filed: February 6, 2002
    Date of Patent: November 9, 2004
    Assignee: Societe de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gérard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 6797715
    Abstract: A method of treating a cancer in warm-blooded animals by administration to the warm-blooded animals in need thereof a camptothecin analog a 7-ring member &bgr;-hydroxy lactone ring of the formula wherein the substituents are defined as in the specification.
    Type: Grant
    Filed: July 7, 2000
    Date of Patent: September 28, 2004
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Patent number: 6762301
    Abstract: A process for the preparation of a compound of the formula wherein the substituents are defined as set forth in the specification comprising reacting a compound of the formula with a 2-halo-3-quinoline-methanol of the formula to obtain a compound of the formula which is then cyclized to form the compound of Formula I.
    Type: Grant
    Filed: January 30, 2002
    Date of Patent: July 13, 2004
    Assignee: Societe de Conseils de Recherches et Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Method for preparing disodium 2,2'-dithiobis(ethanesulphonate)
    Publication number: 20040024246
    Abstract: The invention concerns a novel method for industrial preparation of disodium 2,2′-dithiobis(alkylsulphonates), and in particular disodium 2,2′-dithiobis(ethanesulphate) (dimesna). Said novel method is summarized by the reaction diagram (A). In diagram (A), Hal represents a halogen atom, and preferably a bromine atom; M represents a sodium or potassium atom; and n represents an integer ranging between 0 and 2.
    Type: Application
    Filed: June 16, 2003
    Publication date: February 5, 2004
    Inventors: Jean-Bernard Cazaux, Eric Manginot, Marc Veyrat
  • Preparing amidines derived from 6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid
    Patent number: 6653472
    Abstract: New intermediates of the formula (II)B described below for the synthesis of amidine derivatives of (−)-6-hydroxy-2,5,7,8-tetramethylchromane-2-carboxylic acid, such as for example (S)-N-{4-[4-[(3,4-dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)-carbonyl]-1-piperazinyl]phenyl}-2-thiophenecarboximidamide wherein A′ is X is —Z1—CO; &rgr; is a bond or a heterocycle selected from the group consisting of piperidine, piperazine, homopiperazine, 2-methylpiperazine, 2,5-dimethyl-piperazine and 4-aminopiperidine; Y is —Z2— or —NR3—Z2, R3 is hydrogen, alkyl of 1 to 6 carbon atoms or —COR4, R4 is alkyl of 1 to 6 carbon atoms; Z1 and Z2 independently are a single bond or alkylene of 1 to 6 carbon atoms; and R6 is hydrogen or OH.
    Type: Grant
    Filed: April 26, 2002
    Date of Patent: November 25, 2003
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Christine Le Breton, Eric Manginot, Jean-Bernard Cazaux
  • New analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Publication number: 20030004150
    Abstract: A compound of the formula 1
    Type: Application
    Filed: February 6, 2002
    Publication date: January 2, 2003
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • New analogues of camptothecin, their use as medicaments and the pharmaceutical compositions containing them
    Publication number: 20020160994
    Abstract: A process for the preparation of a compound of the formula 1
    Type: Application
    Filed: January 30, 2002
    Publication date: October 31, 2002
    Applicant: SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Comptothecin analogues, preparation methods therefor, use thereof as drugs, and pharmaceutical compositions containing said analogues
    Patent number: 6339091
    Abstract: The compound of the formula wherein the substituents are defined as in the specification and its non-toxic, pharmaceutically acceptable salts which are useful for the treatment of viral infections, parasitic diseases and the treatment of cancer.
    Type: Grant
    Filed: June 14, 1999
    Date of Patent: January 15, 2002
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S.)
    Inventors: Dennis Bigg, Olivier Lavergne, Francesc Pla Rodas, Jacques Pommier, Gerard Ulibarri, Jerry Harnett, Alain Rolland, Anne-Marie Liberatore, Christophe Lanco, Jean-Bernard Cazaux, Christine Le Breton, Eric Manginot
  • Thienylcyclohexane derivatives for thienylcyclohexyl synthesis
    Patent number: 6107495
    Abstract: Novel thienylcyclohexane derivatives of general formula (I), wherein R' is the 2-thienyl or 3-thienyl radical, R is the cyano radical or a radical of formula --C(O)A, and R2" is a saturated or unsaturated optionally cyclic hydrocarbon radical, or an aryl radical, are disclosed. Methods for preparing said compounds, and the use thereof as novel industrial products for the synthesis of thienylcyclohexyl derivatives, are also disclosed.
    Type: Grant
    Filed: January 19, 1999
    Date of Patent: August 22, 2000
    Assignee: Societe d'Expansion Scientifique Expansia
    Inventors: Jean-Bernard Cazaux, Michel Dafniet, Jean-Marc Kamenka, Eric Manginot