Patents by Inventor Eric McDade

Eric McDade has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS FOR DETECTING CSF TAU SPECIES WITH STAGE AND PROGRESSION OF ALZHEIMER'S DISEASE, AND USE THEREOF
    Publication number: 20250147049
    Abstract: The present disclosure provides methods to quantify and analyze various CSF Tau species and the use thereof to measure pathological features and/or clinical symptoms of tauopathies, including determining the amount of time to dementia due to Alzheimer's disease, determining the time from dementia onset, staging Alzheimer's disease, guiding treatment decisions, and evaluate the clinical efficacy of certain therapeutic interventions.
    Type: Application
    Filed: January 21, 2022
    Publication date: May 8, 2025
    Inventors: Randall Bateman, Eric McDade, Nicolas Barthelemy, Kanta Horie, Yan Li
  • METHODS OF USING AN ANTI-AMYLOID BETA PROTOFIBRIL ANTIBODY AND ANTI-TAU ANTIBODY
    Publication number: 20250051427
    Abstract: Disclosed herein are antibodies, pharmaceutical formulations for treating or preventing Alzheimer's disease, methods of treating or preventing Alzheimer's disease, and kits comprising pharmaceutical formulations for treating or preventing Alzheimer's Disease comprising an anti-A? protofibril antibody and anti-tau antibody.
    Type: Application
    Filed: November 8, 2022
    Publication date: February 13, 2025
    Inventors: Larisa REYDERMAN, Jin ZHOU, Lynn KRAMER, Michael IRIZARRY, Pallavi SACHDEV, Shobha DHADDA, David LI, Kristin WILDSMITH, Pau ACEVES BALDO, Sumit RAWAL, Akihiko KOYAMA, Chad SWANSON, Michio KANEKIYO, June KAPLOW, David VERBEL, Ishani LANDRY, Seiichi HAYATO, Robert GORDON, Randall BATEMAN, Eric MCDADE
  • METHODS OF TREATING BASED ON SITE-SPECIFIC TAU PHOSPHORYLATION
    Publication number: 20230341421
    Abstract: The present disclosure provides methods to quantify tau phosphorylation at specific amino acid residues to predict time to onset of mild cognitive impairment due to Alzheimer's disease, stage Alzheimer's disease, guide treatment decisions, select subjects for clinical trials, and evaluate the clinical efficacy of certain therapeutic interventions.
    Type: Application
    Filed: April 24, 2023
    Publication date: October 26, 2023
    Inventors: Nicolas Barthelemy, Randall Bateman, Eric McDade
  • Methods of treating based on site-specific tau phosphorylation
    Patent number: 11635440
    Abstract: The present disclosure provides methods to quantify tau phosphorylation at specific amino acid residues to predict time to onset of mild cognitive impairment due to Alzheimer's disease, stage Alzheimer's disease, guide treatment decisions, select subjects for clinical trials, and evaluate the clinical efficacy of certain therapeutic interventions.
    Type: Grant
    Filed: June 17, 2022
    Date of Patent: April 25, 2023
    Assignee: Washington University
    Inventors: Nicolas Barthelemy, Randall Bateman, Eric McDade
  • METHODS OF TREATING BASED ON SITE-SPECIFIC TAU PHOSPHORYLATION
    Publication number: 20220317136
    Abstract: The present disclosure provides methods to quantify tau phosphorylation at specific amino acid residues to predict time to onset of mild cognitive impairment due to Alzheimer's disease, stage Alzheimer's disease, guide treatment decisions, select subjects for clinical trials, and evaluate the clinical efficacy of certain therapeutic interventions.
    Type: Application
    Filed: June 17, 2022
    Publication date: October 6, 2022
    Inventors: Nicolas Barthelemy, Randall Bateman, Eric McDade
  • Methods of treating based on site-specific tau phosphorylation
    Patent number: 11402392
    Abstract: The present disclosure provides methods to quantify tau phosphorylation at specific amino acid residues to predict time to onset of mild cognitive impairment due to Alzheimer's disease, stage Alzheimer's disease, guide treatment decisions, select subjects for clinical trials, and evaluate the clinical efficacy of certain therapeutic interventions.
    Type: Grant
    Filed: July 6, 2021
    Date of Patent: August 2, 2022
    Assignee: Washington University
    Inventors: Nicolas Barthelemy, Randall Bateman, Eric McDade
  • METHODS OF TREATING BASED ON SITE-SPECIFIC TAU PHOSPHORYLATION
    Publication number: 20210341495
    Abstract: The present disclosure provides methods to quantify tau phosphorylation at specific amino acid residues to predict time to onset of mild cognitive impairment due to Alzheimer's disease, stage Alzheimer's disease, guide treatment decisions, select subjects for clinical trials, and evaluate the clinical efficacy of certain therapeutic interventions.
    Type: Application
    Filed: July 6, 2021
    Publication date: November 4, 2021
    Inventors: Nicolas Barthelemy, Randall Bateman, Eric McDade
  • Methods of treating based on site-specific tau phosphorylation
    Patent number: 11085935
    Abstract: The present disclosure provides methods to quantify tau phosphorylation at specific amino acid residues to predict time to onset of mild cognitive impairment due to Alzheimer's disease, stage Alzheimer's disease, guide treatment decisions, select subjects for clinical trials, and evaluate the clinical efficacy of certain therapeutic interventions.
    Type: Grant
    Filed: September 9, 2020
    Date of Patent: August 10, 2021
    Assignee: Washington University
    Inventors: Nicolas Barthelemy, Randall Bateman, Eric McDade