Abstract: Valve repair devices are disclosed herein. A valve repair device can include a main shaft and a pair of paddles. Each paddle comprises a connection portion, an inner paddle portion, and an outer paddle portion made from a single metal ribbon-like strip. The ribbon-like material of each connection portion of the pair of paddles extends along the main shaft from a distal end of the main shaft toward a proximal end of the main shaft and the connection portion is connected to the main shaft. The pair of paddles are moveable between an open position and a closed position.

Abstract: Clasps for valve repair devices, valve repair devices and systems are configured to detect proper valve leaflet insertion. The clasp and/or device can have a fixed arm, a moveable arm and a hinge portion hingeably connecting the moveable arm to the fixed arm. The clasp and/or device can include a first marker disposed on the movable arm and an indicator comprising a second marker. The clasp and/or device can be configured such that the first marker is adjacent to the second marker when the movable arm is in the closed position and a leaflet of a native valve is not inserted to a minimum insertion depth in the clasp and the first marker and the second marker are spaced apart when the movable arm is in the closed position and the leaflet of the native valve is inserted to the minimum insertion depth in the clasp.

Abstract: Clasps for valve repair devices, valve repair devices and systems are configured to detect proper valve leaflet insertion. The device can have a paddle and a movable clasp arm. The movable clasp arm can have first and second spaced apart sides. The paddle and the movable clasp arm are moveable to form an opening between the movable clasp arm and the paddle. The device can include an indicator arm disposed between the first and second spaced apart sides of the movable clasp arm. The indicator arm is moveable in the opening to indicate whether a leaflet of the native valve is inserted into the opening between the paddle and the movable clasp arm to at least a minimum desired insertion depth.

Abstract: Valve repair devices are disclosed herein. One valve repair device has a main shaft and a pair of paddles. The pair of paddles include a connection portion, an inner paddle portion, and an outer paddle portion. Each connection portion of the pair of paddles is connected to the main shaft. The pair of paddles are moveable between an open position and a closed position.

Abstract: An implantable device or implant is configured to be positioned within a native heart valve to allow the native heart valve to form a more effective seal. The device can be deployed from a delivery system including one or more lines which can be decoupled from the device by energizing. The device can include contoured clasps which approximate the shape of the native valve when the clasps are in the closed position. The device can include a coaptation element with body portion including a plurality of struts and openings defining a lattice structure. One or more surfaces of one or more components of the device can be coated to improve the visibility of the device during deployment and implantation.

Abstract: A device or implant is configured to be positioned within a native heart valve to allow the native heart valve to form a more effective seal. The device or implant can include connectors that hold movable components of the device together. Components of the device or implant can include flex limiting portions. Paddle frames of the device or implant can be configured to be moved between wide and narrow configurations while substantially maintaining a position where valve leaflets are pressed together by the paddle frames. Paddle frames and/or connectors that widen and narrow the paddle frames can be tapered.

Abstract: An implantable device or implant is configured to be positioned within a native heart valve to allow the native heart valve to form a more effective seal. The implantable device can be removed using one or more of a cutting device, a capture device, and a stabilization component. The stabilization component can control the position of the implantable device while the cutting device resects one or more of the leaflets to which the implantable device is engaged.

Abstract: A handle assembly for controlling the implantable device includes an actuation element extending through a sheath, a paddle actuation control coupled to the actuation element, and a visual indicator. In some implementations, the handle further includes a paddle width adjustment element and a paddle width control that is actuatable to cause axial movement of the paddle width adjustment element, thereby causing a width of the at least one of the pair of paddles of the implantable device to be moved from a first width to a second width. In some implementations, the visual indicator is coupled to the actuation element or the paddle width adjustment element through the handle housing and is configured to provide an indication regarding a configuration of the implantable device.

Abstract: An implantable device or implant is configured to be positioned within a native heart valve to allow the native heart valve to form a more effective seal. In some examples, a plurality of sutures is employed to secure frame portions of the implantable device to a connector of the implantable device. Each of the sutures can be passed through one or more eyelets of the frame portions and the connector. In some examples, an implantable device includes an actuation cap having a flexible portion or a biasing element positioned between an end portion of the actuation cap and an anchor portion of the implantable device. The flexible portion or the biasing element flex or compress responsive to forces between the connector and the actuation cap.

Abstract: A valve repair device for repairing a native valve of a patient. The valve repair device having one or more adjustable width paddle frame portions. The adjustable width paddle frame portions having an anterior portion extending from the medial side of the device to the lateral side of the device and a posterior portion extending from the medial side of the device and a lateral side of the device opposite the anterior portion. The anterior portion and the posterior portion are formed as a single frame member integrally joined at linking portions at the medial side of the device and a lateral side of the device. A connector includes attachment portions that connect to the linking portions to attach the adjustable width frame portion to the connector.

Abstract: A device or implant is configured to be positioned within a native heart valve to allow the native heart valve to form a more effective seal. One or more portions of device or implant can expand and contract. For example, one or more portions of the device or implant can narrow during delivery and expand on implantation on the native heart valve. Delivery systems are configured to narrow and expand the one or more portions of the device or implant.

Abstract: Valve repair devices are disclosed herein. The valve repair devices are configured to reduce or inhibit regurgitant blood flow through a native heart valve. The valve repair devices are configured to be positioned within the native heart valve orifice and attached to the native heart valve. The device can be connected to leaflets of the native valve by a variety of different types of paddles.

Abstract: An implantable device or implant is configured to be positioned within a native heart valve to allow the native heart valve to form a more effective seal. The implantable device or implant can include a pair of paddles frame a coaptation element. The coaptation element defines a first area when viewed from above. The paddle frames define when viewed from above. A ratio of the second area to the first area is greater than or equal to 2 to 1.

Abstract: Valve repair devices and systems configured to detect proper valve leaflet insertion. The device/system can have a pair of paddles and a clasp attached to each of the paddles. The clasps can have a fixed arm attached to the paddle, a movable arm connected to the fixed arm that is movable between an open position and a closed position. The device can have an indicator that can move between not engaged by a leaflet and engaged by a leaflet conditions to indicate capture of a leaflet of the native valve. The indicator can be compressible. The indicator can be flattenable. The indicator can include one or more marker.

Abstract: Valve repair devices and systems configured to detect proper valve leaflet insertion. The device/system can have a pair of paddles and a clasp attached to each of the paddles. The clasps may have a fixed arm attached to the paddle, a movable arm connected to the fixed arm that is movable between an open position and a closed position, and an indicator arm connected to at least one of the fixed arm and the movable arm. The indicator arm can move between a first position when not engaged with a leaflet and a second, engaged position when engaged with the leaflet. Movement of the indicator arm from the first position to the second, engaged position indicates capture of a leaflet of the native valve by the pair of paddles.

Abstract: An implantable device or implant is configured to be positioned within a native heart valve to allow the native heart valve to form a more effective seal. In some implementations, the implantable device or implant, or one or more portions thereof, can be configured to expand and/or contract. For example, the implantable device or implant can narrow during delivery and expand on implantation on the native heart valve.

Abstract: Example valve repair devices for repairing a native valve of a patient include expandable coaptation portions. One coaptation portion has an opening and an expandable portion that is configured to expand outward through the opening. An actuation element or actuation member engages the expandable portion to expand and retract the expandable portion.

Abstract: Valve repair devices are disclosed herein. One valve repair device has a main shaft and a pair of paddles. The pair of paddles include a connection portion, an inner paddle portion, and an outer paddle portion. Each connection portion of the pair of paddles is connected to the main shaft. The pair of paddles are moveable between an open position and a closed position.

Abstract: Valve repair devices and systems configured to detect proper valve leaflet insertion. The device/system can have a pair of paddles and a clasp attached to each of the paddles. The clasps may have a fixed arm attached to the paddle, a movable arm connected to the fixed arm that is movable between an open position and a closed position, and an indicator arm connected to at least one of the fixed arm and the movable arm. The indicator arm can move between a first position when not engaged with a leaflet and a second, engaged position when engaged with the leaflet. Movement of the indicator arm from the first position to the second, engaged position indicates capture of a leaflet of the native valve by the pair of paddles.